7C9N

Crystal structure of SETDB1 tudor domain in complexed with Compound 1.

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue FN9 B 501

Chain	Residue
A	TRP275
A	FN9501
B	THR212
B	TYR268
B	TRP275
B	ASP299
B	TYR301
B	GLU386

---

site_id	AC2
Number of Residues	7
Details	binding site for residue FN9 A 501

Chain	Residue
A	ASP299
A	TYR301
A	GLU386
A	ARG394
B	TRP275
B	FN9501
A	TYR268

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	100
Details	Domain: {"description":"Tudor 1; degenerate","evidences":[{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	126
Details	Domain: {"description":"Tudor 2","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	112
Details	Domain: {"description":"Tudor 3","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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