7C5C

Crystal structure of SeFRS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004831	molecular_function	tyrosine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006437	biological_process	tyrosyl-tRNA aminoacylation
A	0016874	molecular_function	ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue EDO A 401

Chain	Residue
A	HIS42
A	GLY44
A	GLN48
A	LYS204
A	HOH617

---

site_id	AC2
Number of Residues	2
Details	binding site for residue EDO A 402

Chain	Residue
A	ASP2
A	GLU5

---

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	10
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGkIHLGHY

Chain	Residue	Details
A	PRO37-TYR46

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Region: {"description":"Tyrosine"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Region: {"description":"Interaction with t-RNA"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Motif: {"description":"'HIGH' region"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Motif: {"description":"'KMSKS' region"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12754495","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	1
Details	Site: {"description":"Interaction with t-RNA"}

Chain

Residue

Details

---