Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004675 | molecular_function | transmembrane receptor protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007178 | biological_process | cell surface receptor protein serine/threonine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004675 | molecular_function | transmembrane receptor protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007178 | biological_process | cell surface receptor protein serine/threonine kinase signaling pathway |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue FH0 A 501 |
| Chain | Residue |
| A | VAL214 |
| A | GLU287 |
| A | MET288 |
| A | GLY289 |
| A | SER290 |
| A | ASP293 |
| A | LYS340 |
| A | LEU343 |
| A | HOH606 |
| A | HOH712 |
| B | ASN421 |
| A | VAL222 |
| B | ASN459 |
| B | ARG460 |
| B | SER463 |
| A | ALA233 |
| A | LYS235 |
| A | LEU263 |
| A | THR283 |
| A | HIS284 |
| A | TYR285 |
| A | HIS286 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | GLY217 |
| A | ARG218 |
| A | TYR219 |
| A | LYS340 |
| A | HOH607 |
| A | HOH608 |
| A | HOH609 |
| A | HOH711 |
| A | HOH773 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | PHE431 |
| A | ASP433 |
| A | GLN453 |
| A | ARG454 |
| A | ASN456 |
| A | HOH741 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | LYS243 |
| B | LYS243 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | HIS284 |
| A | HIS286 |
| A | LYS345 |
| A | LYS346 |
| A | HOH621 |
| A | HOH684 |
| A | HOH690 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | ARG218 |
| A | LYS340 |
| A | ARG380 |
| A | ASP438 |
| A | PRO439 |
| A | HOH602 |
| A | HOH696 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 507 |
| Chain | Residue |
| A | GLN363 |
| A | SER364 |
| A | HOH640 |
| A | HOH694 |
| B | ILE321 |
| B | LYS400 |
| B | ALA488 |
| B | LEU489 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 508 |
| Chain | Residue |
| A | ILE321 |
| A | LYS400 |
| A | ALA488 |
| A | LEU489 |
| A | HOH683 |
| B | GLN363 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 509 |
| Chain | Residue |
| A | ASP301 |
| A | THR302 |
| A | HOH603 |
| A | HOH671 |
| A | HOH729 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 510 |
| Chain | Residue |
| A | PHE324 |
| A | HOH605 |
| A | HOH734 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 511 |
| Chain | Residue |
| A | TYR294 |
| A | THR298 |
| A | THR299 |
| A | LEU300 |
| A | ASP301 |
| A | SER304 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 512 |
| Chain | Residue |
| A | ARG307 |
| A | HOH657 |
| A | HOH673 |
| A | HOH722 |
| site_id | AD4 |
| Number of Residues | 20 |
| Details | binding site for residue FH0 B 501 |
| Chain | Residue |
| B | ASP293 |
| B | LYS340 |
| B | LEU343 |
| B | HOH605 |
| B | HOH698 |
| B | HOH762 |
| A | PHE462 |
| A | SER463 |
| B | VAL214 |
| B | VAL222 |
| B | ALA233 |
| B | LYS235 |
| B | LEU263 |
| B | THR283 |
| B | HIS284 |
| B | TYR285 |
| B | HIS286 |
| B | GLU287 |
| B | GLY289 |
| B | SER290 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | ARG218 |
| B | ARG380 |
| B | ASN437 |
| B | ASP438 |
| B | PRO439 |
| B | HOH702 |
| B | HOH713 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | PHE431 |
| B | ASP433 |
| B | ARG454 |
| B | ASN456 |
| B | HOH683 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| A | GLU242 |
| B | GLU242 |
| B | LYS243 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| B | ARG218 |
| B | TYR219 |
| B | LYS340 |
| B | HOH607 |
| B | HOH626 |
| B | HOH663 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 506 |
| Chain | Residue |
| A | ASN231 |
| A | HOH700 |
| B | TYR479 |
| B | GLN480 |
| B | ASN481 |
| B | HOH655 |
| B | HOH706 |
| B | HOH709 |
| B | HOH735 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 507 |
| Chain | Residue |
| B | HIS286 |
| B | LYS345 |
| B | LYS346 |
| B | HOH613 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 508 |
| Chain | Residue |
| B | ASP301 |
| B | THR302 |
| B | HOH711 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 509 |
| Chain | Residue |
| A | LEU489 |
| B | PHE324 |
| B | SER364 |
| B | HOH651 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 510 |
| Chain | Residue |
| B | THR299 |
| B | LEU300 |
| B | ASP301 |
| B | SER304 |
| B | HOH611 |
| B | HOH737 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 511 |
| Chain | Residue |
| B | ARG307 |
| B | HOH601 |
| B | HOH612 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 22 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGKGRYGEVWrGswqgen............VAVK |
| Chain | Residue | Details |
| A | VAL214-LYS235 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IaHrDLKskNILV |
| Chain | Residue | Details |
| A | ILE332-VAL344 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
