7C34

Crystal structure of Serratia marcescens Chitinase B complexed with Berberine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0008061	molecular_function	chitin binding
A	0030246	molecular_function	carbohydrate binding
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0005576	cellular_component	extracellular region
B	0005975	biological_process	carbohydrate metabolic process
B	0008061	molecular_function	chitin binding
B	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue BER A 501

Chain	Residue
A	PHE191
A	ASP215
A	TRP220
A	ASP316

---

site_id	AC2
Number of Residues	6
Details	binding site for residue BER B 501

Chain	Residue
B	ASP316
A	TYR481
B	TRP97
B	PHE191
B	ASP215
B	TRP220

---

Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGVDIDwE

Chain	Residue	Details
A	PHE136-GLU144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	766
Details	Domain: {"description":"GH18","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	120
Details	Domain: {"description":"Chitin-binding type-3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---