7C2B

Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin f2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016730	molecular_function	oxidoreductase activity, acting on iron-sulfur proteins as donors
B	0015979	biological_process	photosynthesis
C	0015035	molecular_function	protein-disulfide reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SF4 A 201

Chain	Residue
A	CYS54
A	CYS73
A	CYS75
A	MET78
A	CYS84
A	HIS85
A	CYS86

---

site_id	AC2
Number of Residues	4
Details	binding site for residue NO3 A 202

Chain	Residue
B	ASN79
C	VAL81
A	ARG57
A	HOH301

---

site_id	AC3
Number of Residues	4
Details	binding site for residue NO3 A 203

Chain	Residue
A	ARG23
C	TRP19
C	PRO20
C	LYS23

---

site_id	AC4
Number of Residues	7
Details	binding site for residue NO3 A 204

Chain	Residue
A	ARG57
A	TRP71
A	HIS85
A	HOH353
A	HOH375
B	ASN79
C	VAL81

---

site_id	AC5
Number of Residues	2
Details	binding site for residue NO3 A 205

Chain	Residue
A	VAL37
A	THR112

---

site_id	AC6
Number of Residues	1
Details	binding site for residue NO3 A 206

Chain	Residue
A	ASP31

---

site_id	AC7
Number of Residues	4
Details	binding site for residue NO3 A 207

Chain	Residue
A	GLN68
A	PHE70
A	HOH364
B	HIS101

---

site_id	AC8
Number of Residues	3
Details	binding site for residue NO3 B 201

Chain	Residue
A	PRO77
A	GLU83
B	ASN79

---

site_id	AC9
Number of Residues	7
Details	binding site for residue NO3 C 201

Chain	Residue
A	MET13
A	LYS46
A	PRO52
A	ASN72
C	LYS92
C	VAL94
C	HOH310

---

site_id	AD1
Number of Residues	5
Details	binding site for residue NO3 C 202

Chain	Residue
A	LYS46
C	LYS89
C	VAL94
C	LYS95
C	ALA112

---

site_id	AD2
Number of Residues	8
Details	binding site for residue NO3 C 203

Chain	Residue
A	HIS58
A	TYR59
A	LYS62
C	CYS66
C	ASN67
C	GLN68
C	LYS71
C	HOH333

---

site_id	AD3
Number of Residues	6
Details	binding site for residue NO3 C 204

Chain	Residue
A	HIS58
A	ASP60
C	LYS71
C	LYS75
C	ARG80
C	HOH354

---

site_id	AD4
Number of Residues	5
Details	binding site for residue NO3 C 205

Chain	Residue
C	TYR35
C	SER42
C	HOH304
C	HOH307
C	HOH367

---

site_id	AD5
Number of Residues	3
Details	binding site for residue NO3 C 206

Chain	Residue
C	GLU96
C	HOH337
C	HOH373

---

site_id	AD6
Number of Residues	4
Details	binding site for residue NO3 C 207

Chain	Residue
B	MET58
C	GLU110
C	ARG113
C	HOH326

---

site_id	AD7
Number of Residues	6
Details	binding site for residue MG C 208

Chain	Residue
A	HOH336
A	HOH369
C	HOH314
C	HOH363
C	HOH378
C	HOH394

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"Q55389","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33015914","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7BZK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7C2B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7C3F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Increases the nucleophilicity of the active site Cys","evidences":[{"source":"UniProtKB","id":"Q55389","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Deprotonates C-terminal active site Cys","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Contributes to redox potential value","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"S-glutathionyl cysteine; transient","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---