7C22

Crystal structure of the C-terminal domain of SARS-CoV-2 nucleocapsid protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0019013	cellular_component	viral nucleocapsid
B	0003723	molecular_function	RNA binding
B	0019013	cellular_component	viral nucleocapsid
C	0003723	molecular_function	RNA binding
C	0019013	cellular_component	viral nucleocapsid
D	0003723	molecular_function	RNA binding
D	0019013	cellular_component	viral nucleocapsid

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue ACT A 501

Chain	Residue
A	GLU323

---

site_id	AC2
Number of Residues	2
Details	binding site for residue PEG A 502

Chain	Residue
A	LYS266
A	ASP297

---

site_id	AC3
Number of Residues	1
Details	binding site for residue ACT C 401

Chain	Residue
D	ALA336

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	412
Details	Region: {"description":"Dimerization","evidences":[{"source":"HAMAP-Rule","id":"MF_04096","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	320
Details	Region: {"description":"Putative NLRP3 binding","evidences":[{"source":"PubMed","id":"34341353","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"UniProtKB","id":"P59595","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---