Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004333 | molecular_function | fumarate hydratase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006106 | biological_process | fumarate metabolic process |
| A | 0006108 | biological_process | malate metabolic process |
| A | 0016829 | molecular_function | lyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004333 | molecular_function | fumarate hydratase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0006106 | biological_process | fumarate metabolic process |
| B | 0006108 | biological_process | malate metabolic process |
| B | 0016829 | molecular_function | lyase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004333 | molecular_function | fumarate hydratase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0006106 | biological_process | fumarate metabolic process |
| C | 0006108 | biological_process | malate metabolic process |
| C | 0016829 | molecular_function | lyase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004333 | molecular_function | fumarate hydratase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0006106 | biological_process | fumarate metabolic process |
| D | 0006108 | biological_process | malate metabolic process |
| D | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | ALA39 |
| A | MET41 |
| A | HIS43 |
| A | ASP87 |
| A | PHE90 |
| A | HOH630 |
| A | HOH678 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | HOH666 |
| A | HOH667 |
| A | GLN400 |
| A | ASP404 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | HIS416 |
| A | TRP454 |
| A | ASP459 |
| A | HOH660 |
| D | LEU237 |
| D | HOH776 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | LYS246 |
| A | GLU249 |
| A | TYR250 |
| A | LYS253 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | ASP181 |
| A | VAL183 |
| A | GLN400 |
| A | HOH632 |
| A | HOH635 |
| A | HOH909 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | ASP404 |
| A | SER405 |
| A | HOH860 |
| A | HOH906 |
| A | HOH916 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 508 |
| Chain | Residue |
| A | GLN375 |
| A | ASP379 |
| A | HOH789 |
| A | HOH853 |
| B | LYS34 |
| B | GLY36 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| B | ALA39 |
| B | MET41 |
| B | HIS43 |
| B | ASP87 |
| B | PHE90 |
| B | HOH776 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | PRO303 |
| B | GLY324 |
| B | HOH602 |
| B | HOH725 |
| B | HOH762 |
| B | HOH818 |
| D | LYS427 |
| D | HIS430 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| B | GLY121 |
| B | LYS122 |
| B | GLU125 |
| B | ILE441 |
| B | HOH607 |
| B | HOH714 |
| B | HOH730 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| A | HOH648 |
| B | GLN340 |
| B | GLN372 |
| B | HOH781 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | ALA39 |
| C | MET41 |
| C | HIS43 |
| C | ASP87 |
| C | PHE90 |
| C | HOH689 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 502 |
| Chain | Residue |
| A | HIS430 |
| C | PRO303 |
| C | GLY324 |
| C | HOH685 |
| C | HOH727 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | ILE312 |
| C | PRO313 |
| C | GLU314 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 501 |
| Chain | Residue |
| D | ALA39 |
| D | MET41 |
| D | HIS43 |
| D | ASP87 |
| D | PHE90 |
| D | HOH676 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 502 |
| Chain | Residue |
| C | LYS34 |
| C | GLY36 |
| D | GLN375 |
| D | ASP379 |
| D | HOH669 |
| D | HOH801 |
| D | HOH842 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 503 |
| Chain | Residue |
| C | GLN375 |
| C | ASP379 |
| D | LYS34 |
| D | GLY36 |
| D | HOH712 |
| D | HOH839 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 504 |
| Chain | Residue |
| D | HOH700 |
| D | HOH735 |
| B | HIS430 |
| D | PRO303 |
| D | GLY324 |
Functional Information from PROSITE/UniProt
| site_id | PS00163 |
| Number of Residues | 10 |
| Details | FUMARATE_LYASES Fumarate lyases signature. GSsiMpGKvN |
| Chain | Residue | Details |
| A | GLY318-ASN327 | |
