7C18

Crystal structure of FumaraseC from Mannheimia succiniciproducens in complex with Fumarate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004333	molecular_function	fumarate hydratase activity
A	0005737	cellular_component	cytoplasm
A	0006099	biological_process	tricarboxylic acid cycle
A	0006106	biological_process	fumarate metabolic process
A	0006108	biological_process	malate metabolic process
A	0016829	molecular_function	lyase activity
A	0045239	cellular_component	tricarboxylic acid cycle heteromeric enzyme complex
B	0003824	molecular_function	catalytic activity
B	0004333	molecular_function	fumarate hydratase activity
B	0005737	cellular_component	cytoplasm
B	0006099	biological_process	tricarboxylic acid cycle
B	0006106	biological_process	fumarate metabolic process
B	0006108	biological_process	malate metabolic process
B	0016829	molecular_function	lyase activity
B	0045239	cellular_component	tricarboxylic acid cycle heteromeric enzyme complex
C	0003824	molecular_function	catalytic activity
C	0004333	molecular_function	fumarate hydratase activity
C	0005737	cellular_component	cytoplasm
C	0006099	biological_process	tricarboxylic acid cycle
C	0006106	biological_process	fumarate metabolic process
C	0006108	biological_process	malate metabolic process
C	0016829	molecular_function	lyase activity
C	0045239	cellular_component	tricarboxylic acid cycle heteromeric enzyme complex
D	0003824	molecular_function	catalytic activity
D	0004333	molecular_function	fumarate hydratase activity
D	0005737	cellular_component	cytoplasm
D	0006099	biological_process	tricarboxylic acid cycle
D	0006106	biological_process	fumarate metabolic process
D	0006108	biological_process	malate metabolic process
D	0016829	molecular_function	lyase activity
D	0045239	cellular_component	tricarboxylic acid cycle heteromeric enzyme complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue FUM A 501

Chain	Residue
A	GLY318
B	SER141
B	ASN142
C	THR188
C	HIS189
A	CYS319
A	SER320
A	ILE321
A	MET322
A	LYS325
A	ASN327
B	THR101
B	SER140

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site_id	AC2
Number of Residues	12
Details	binding site for residue FUM A 502

Chain	Residue
A	THR101
A	SER140
A	SER141
A	ASN142
B	CYS319
B	SER320
B	ILE321
B	MET322
B	LYS325
B	ASN327
D	THR188
D	HIS189

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site_id	AC3
Number of Residues	13
Details	binding site for residue FUM C 501

Chain	Residue
A	THR188
A	HIS189
C	GLY318
C	CYS319
C	SER320
C	ILE321
C	MET322
C	LYS325
C	ASN327
D	THR101
D	SER140
D	SER141
D	ASN142

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site_id	AC4
Number of Residues	13
Details	binding site for residue FUM C 502

Chain	Residue
B	THR188
B	HIS189
C	THR101
C	SER140
C	SER141
C	ASN142
D	GLY318
D	CYS319
D	SER320
D	ILE321
D	MET322
D	LYS325
D	ASN327

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