7BV6

Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
B	0005484	molecular_function	SNAP receptor activity
B	0006886	biological_process	intracellular protein transport
B	0016020	cellular_component	membrane
E	0016020	cellular_component	membrane
E	0016192	biological_process	vesicle-mediated transport
F	0005484	molecular_function	SNAP receptor activity
F	0006886	biological_process	intracellular protein transport
F	0016020	cellular_component	membrane
I	0016020	cellular_component	membrane
I	0016192	biological_process	vesicle-mediated transport
J	0005484	molecular_function	SNAP receptor activity
J	0006886	biological_process	intracellular protein transport
J	0016020	cellular_component	membrane
M	0016020	cellular_component	membrane
M	0016192	biological_process	vesicle-mediated transport
N	0005484	molecular_function	SNAP receptor activity
N	0006886	biological_process	intracellular protein transport
N	0016020	cellular_component	membrane
Q	0016020	cellular_component	membrane
Q	0016192	biological_process	vesicle-mediated transport
R	0005484	molecular_function	SNAP receptor activity
R	0006886	biological_process	intracellular protein transport
R	0016020	cellular_component	membrane
U	0016020	cellular_component	membrane
U	0016192	biological_process	vesicle-mediated transport
V	0005484	molecular_function	SNAP receptor activity
V	0006886	biological_process	intracellular protein transport
V	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00417
Number of Residues	20
Details	SYNAPTOBREVIN Synaptobrevin signature. NVERIlARgeNLEhLrNKTE

Chain	Residue	Details
A	ASN30-GLU49

---

site_id	PS00914
Number of Residues	40
Details	SYNTAXIN Syntaxin / epimorphin family signature. AaesWetLEadLiELsqLVtdFsllVnsQQekIDsIAdh.V

Chain	Residue	Details
B	ALA168-VAL207

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	300
Details	Domain: {"description":"v-SNARE coiled-coil homology","evidences":[{"source":"PROSITE-ProRule","id":"PRU00290","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Site: {"description":"Interaction with STX8","evidences":[{"source":"UniProtKB","id":"Q9WUF4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Lipidation: {"description":"(Microbial infection) N6-stearoyl lysine","evidences":[{"source":"PubMed","id":"30061757","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	186
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	310
Details	Domain: {"description":"t-SNARE coiled-coil homology","evidences":[{"source":"PROSITE-ProRule","id":"PRU00202","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---