Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0002039 | molecular_function | p53 binding |
A | 0005634 | cellular_component | nucleus |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
A | 0042054 | molecular_function | histone methyltransferase activity |
B | 0002039 | molecular_function | p53 binding |
B | 0005634 | cellular_component | nucleus |
B | 0008270 | molecular_function | zinc ion binding |
B | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
B | 0042054 | molecular_function | histone methyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 1501 |
Chain | Residue |
A | CYS980 |
A | CYS1017 |
A | CYS1023 |
A | CYS1027 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue ZN A 1502 |
Chain | Residue |
A | CYS974 |
A | CYS987 |
A | CYS1017 |
A | CYS1021 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue ZN A 1503 |
Chain | Residue |
A | CYS976 |
A | CYS980 |
A | CYS985 |
A | CYS974 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue ZN A 1504 |
Chain | Residue |
A | CYS1115 |
A | CYS1168 |
A | CYS1170 |
A | CYS1175 |
site_id | AC5 |
Number of Residues | 18 |
Details | binding site for residue SAM A 1505 |
Chain | Residue |
A | MET1048 |
A | TRP1050 |
A | SER1084 |
A | TYR1085 |
A | ARG1109 |
A | PHE1110 |
A | ASN1112 |
A | HIS1113 |
A | TYR1154 |
A | PHE1158 |
A | PHE1166 |
A | THR1167 |
A | CYS1168 |
A | GLN1169 |
A | N471506 |
A | HOH1652 |
A | HOH1677 |
A | HOH1686 |
site_id | AC6 |
Number of Residues | 14 |
Details | binding site for residue N47 A 1506 |
Chain | Residue |
A | TYR1067 |
A | ALA1077 |
A | ASP1078 |
A | ASP1083 |
A | SER1084 |
A | LEU1086 |
A | ASP1088 |
A | VAL1096 |
A | CYS1098 |
A | TYR1154 |
A | ARG1157 |
A | PHE1158 |
A | SAM1505 |
A | HOH1641 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue ZN B 1501 |
Chain | Residue |
B | CYS980 |
B | CYS1017 |
B | CYS1023 |
B | CYS1027 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue ZN B 1502 |
Chain | Residue |
B | CYS974 |
B | CYS987 |
B | CYS1017 |
B | CYS1021 |
B | ZN1503 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue ZN B 1503 |
Chain | Residue |
B | CYS974 |
B | CYS976 |
B | CYS980 |
B | CYS985 |
B | ZN1502 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue ZN B 1504 |
Chain | Residue |
B | CYS1115 |
B | CYS1168 |
B | CYS1170 |
B | CYS1175 |
site_id | AD2 |
Number of Residues | 20 |
Details | binding site for residue SAM B 1505 |
Chain | Residue |
B | MET1048 |
B | TRP1050 |
B | SER1084 |
B | TYR1085 |
B | ARG1109 |
B | PHE1110 |
B | ASN1112 |
B | HIS1113 |
B | TYR1154 |
B | PHE1158 |
B | PHE1166 |
B | THR1167 |
B | CYS1168 |
B | GLN1169 |
B | N471506 |
B | HOH1642 |
B | HOH1725 |
B | HOH1727 |
B | HOH1744 |
B | HOH1756 |
site_id | AD3 |
Number of Residues | 14 |
Details | binding site for residue N47 B 1506 |
Chain | Residue |
B | HOH1653 |
B | TYR1067 |
B | ASP1074 |
B | ALA1077 |
B | ASP1078 |
B | ASP1083 |
B | SER1084 |
B | LEU1086 |
B | ASP1088 |
B | CYS1098 |
B | TYR1154 |
B | ARG1157 |
B | PHE1158 |
B | SAM1505 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 34 |
Details | BINDING: |
Chain | Residue | Details |
A | CYS974 | |
A | MET1048 | |
A | TYR1085 | |
A | ASN1112 | |
A | CYS1115 | |
A | CYS1168 | |
A | GLN1169 | |
A | CYS1170 | |
A | CYS1175 | |
B | CYS974 | |
B | CYS976 | |
A | CYS976 | |
B | CYS980 | |
B | CYS985 | |
B | CYS987 | |
B | CYS1017 | |
B | CYS1021 | |
B | CYS1023 | |
B | CYS1027 | |
B | MET1048 | |
B | TYR1085 | |
B | ASN1112 | |
A | CYS980 | |
B | CYS1115 | |
B | CYS1168 | |
B | GLN1169 | |
B | CYS1170 | |
B | CYS1175 | |
A | CYS985 | |
A | CYS987 | |
A | CYS1017 | |
A | CYS1021 | |
A | CYS1023 | |
A | CYS1027 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Histone H3K9me binding => ECO:0000250 |
Chain | Residue | Details |
A | TYR1067 | |
B | TYR1067 | |