7BTE
Lifeact-F-actin complex
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001725 | cellular_component | stress fiber |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005856 | cellular_component | cytoskeleton |
A | 0005865 | cellular_component | striated muscle thin filament |
A | 0005884 | cellular_component | actin filament |
A | 0016787 | molecular_function | hydrolase activity |
A | 0030240 | biological_process | skeletal muscle thin filament assembly |
A | 0048741 | biological_process | skeletal muscle fiber development |
C | 0001725 | cellular_component | stress fiber |
C | 0005515 | molecular_function | protein binding |
C | 0005524 | molecular_function | ATP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005856 | cellular_component | cytoskeleton |
C | 0005865 | cellular_component | striated muscle thin filament |
C | 0005884 | cellular_component | actin filament |
C | 0016787 | molecular_function | hydrolase activity |
C | 0030240 | biological_process | skeletal muscle thin filament assembly |
C | 0048741 | biological_process | skeletal muscle fiber development |
E | 0001725 | cellular_component | stress fiber |
E | 0005515 | molecular_function | protein binding |
E | 0005524 | molecular_function | ATP binding |
E | 0005737 | cellular_component | cytoplasm |
E | 0005856 | cellular_component | cytoskeleton |
E | 0005865 | cellular_component | striated muscle thin filament |
E | 0005884 | cellular_component | actin filament |
E | 0016787 | molecular_function | hydrolase activity |
E | 0030240 | biological_process | skeletal muscle thin filament assembly |
E | 0048741 | biological_process | skeletal muscle fiber development |
G | 0001725 | cellular_component | stress fiber |
G | 0005515 | molecular_function | protein binding |
G | 0005524 | molecular_function | ATP binding |
G | 0005737 | cellular_component | cytoplasm |
G | 0005856 | cellular_component | cytoskeleton |
G | 0005865 | cellular_component | striated muscle thin filament |
G | 0005884 | cellular_component | actin filament |
G | 0016787 | molecular_function | hydrolase activity |
G | 0030240 | biological_process | skeletal muscle thin filament assembly |
G | 0048741 | biological_process | skeletal muscle fiber development |
I | 0001725 | cellular_component | stress fiber |
I | 0005515 | molecular_function | protein binding |
I | 0005524 | molecular_function | ATP binding |
I | 0005737 | cellular_component | cytoplasm |
I | 0005856 | cellular_component | cytoskeleton |
I | 0005865 | cellular_component | striated muscle thin filament |
I | 0005884 | cellular_component | actin filament |
I | 0016787 | molecular_function | hydrolase activity |
I | 0030240 | biological_process | skeletal muscle thin filament assembly |
I | 0048741 | biological_process | skeletal muscle fiber development |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 1 |
Details | binding site for residue MG A 401 |
Chain | Residue |
A | ADP402 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue ADP A 402 |
Chain | Residue |
A | GLY298 |
A | TYR302 |
A | LYS332 |
A | MG401 |
A | GLY9 |
A | SER10 |
A | GLY11 |
A | LEU12 |
A | GLY152 |
A | ASP153 |
A | LYS209 |
A | GLU210 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue MG C 801 |
Chain | Residue |
C | GLN505 |
C | ASP522 |
C | ADP802 |
site_id | AC4 |
Number of Residues | 15 |
Details | binding site for residue ADP C 802 |
Chain | Residue |
C | GLY381 |
C | SER382 |
C | GLY383 |
C | LEU384 |
C | LYS386 |
C | GLN505 |
C | SER523 |
C | GLY524 |
C | ASP525 |
C | GLU582 |
C | GLY670 |
C | THR671 |
C | TYR674 |
C | LYS704 |
C | MG801 |
site_id | AC5 |
Number of Residues | 2 |
Details | binding site for residue MG E 1201 |
Chain | Residue |
E | GLN877 |
E | ADP1202 |
site_id | AC6 |
Number of Residues | 12 |
Details | binding site for residue ADP E 1202 |
Chain | Residue |
E | GLY753 |
E | SER754 |
E | LEU756 |
E | LYS758 |
E | GLY896 |
E | ASP897 |
E | GLU954 |
E | GLY1042 |
E | THR1043 |
E | TYR1046 |
E | LYS1076 |
E | MG1201 |
site_id | AC7 |
Number of Residues | 2 |
Details | binding site for residue MG G 1501 |
Chain | Residue |
G | LYS1130 |
G | ADP1502 |
site_id | AC8 |
Number of Residues | 13 |
Details | binding site for residue ADP G 1502 |
Chain | Residue |
G | GLY1125 |
G | SER1126 |
G | GLY1127 |
G | LEU1128 |
G | LYS1130 |
G | GLN1249 |
G | GLY1268 |
G | ASP1269 |
G | GLU1326 |
G | GLY1414 |
G | TYR1418 |
G | LYS1448 |
G | MG1501 |
site_id | AC9 |
Number of Residues | 3 |
Details | binding site for residue MG I 1901 |
Chain | Residue |
I | GLY1640 |
I | ASP1641 |
I | ADP1902 |
site_id | AD1 |
Number of Residues | 10 |
Details | binding site for residue ADP I 1902 |
Chain | Residue |
I | GLY1497 |
I | LEU1500 |
I | GLY1640 |
I | ASP1641 |
I | LYS1697 |
I | GLU1698 |
I | GLY1786 |
I | TYR1790 |
I | LYS1820 |
I | MG1901 |
Functional Information from PROSITE/UniProt
site_id | PS00406 |
Number of Residues | 11 |
Details | ACTINS_1 Actins signature 1. YVGDEAQs.KRG |
Chain | Residue | Details |
A | TYR49-GLY59 |
site_id | PS00432 |
Number of Residues | 9 |
Details | ACTINS_2 Actins signature 2. WITKqEYDE |
Chain | Residue | Details |
A | TRP352-GLU360 |
site_id | PS01132 |
Number of Residues | 13 |
Details | ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR |
Chain | Residue | Details |
A | LEU100-ARG112 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 5 |
Details | MOD_RES: N-acetylcysteine; in intermediate form => ECO:0000250|UniProtKB:P62737 |
Chain | Residue | Details |
A | CYS-4 | |
C | CYS368 | |
E | CYS740 | |
G | CYS1112 | |
I | CYS1484 |
site_id | SWS_FT_FI2 |
Number of Residues | 5 |
Details | MOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:456601 |
Chain | Residue | Details |
A | ASP-3 | |
C | ASP369 | |
E | ASP741 | |
G | ASP1113 | |
I | ASP1485 |
site_id | SWS_FT_FI3 |
Number of Residues | 10 |
Details | MOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134 |
Chain | Residue | Details |
A | MET40 | |
I | MET1531 | |
A | MET43 | |
C | MET412 | |
C | MET415 | |
E | MET784 | |
E | MET787 | |
G | MET1156 | |
G | MET1159 | |
I | MET1528 |
site_id | SWS_FT_FI4 |
Number of Residues | 5 |
Details | MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:12356759, ECO:0007744|PDB:1MDU |
Chain | Residue | Details |
A | HIS69 | |
C | HIS441 | |
E | HIS813 | |
G | HIS1185 | |
I | HIS1557 |
site_id | SWS_FT_FI5 |
Number of Residues | 5 |
Details | MOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133 |
Chain | Residue | Details |
A | LYS80 | |
C | LYS452 | |
E | LYS824 | |
G | LYS1196 | |
I | LYS1568 |