7BTE
Lifeact-F-actin complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001725 | cellular_component | stress fiber |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005865 | cellular_component | striated muscle thin filament |
| A | 0005884 | cellular_component | actin filament |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030240 | biological_process | skeletal muscle thin filament assembly |
| A | 0048741 | biological_process | skeletal muscle fiber development |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0001725 | cellular_component | stress fiber |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005856 | cellular_component | cytoskeleton |
| C | 0005865 | cellular_component | striated muscle thin filament |
| C | 0005884 | cellular_component | actin filament |
| C | 0015629 | cellular_component | actin cytoskeleton |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0030240 | biological_process | skeletal muscle thin filament assembly |
| C | 0048741 | biological_process | skeletal muscle fiber development |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0001725 | cellular_component | stress fiber |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005856 | cellular_component | cytoskeleton |
| E | 0005865 | cellular_component | striated muscle thin filament |
| E | 0005884 | cellular_component | actin filament |
| E | 0015629 | cellular_component | actin cytoskeleton |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0030240 | biological_process | skeletal muscle thin filament assembly |
| E | 0048741 | biological_process | skeletal muscle fiber development |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0001725 | cellular_component | stress fiber |
| G | 0005515 | molecular_function | protein binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005856 | cellular_component | cytoskeleton |
| G | 0005865 | cellular_component | striated muscle thin filament |
| G | 0005884 | cellular_component | actin filament |
| G | 0015629 | cellular_component | actin cytoskeleton |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0030240 | biological_process | skeletal muscle thin filament assembly |
| G | 0048741 | biological_process | skeletal muscle fiber development |
| I | 0000166 | molecular_function | nucleotide binding |
| I | 0001725 | cellular_component | stress fiber |
| I | 0005515 | molecular_function | protein binding |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005856 | cellular_component | cytoskeleton |
| I | 0005865 | cellular_component | striated muscle thin filament |
| I | 0005884 | cellular_component | actin filament |
| I | 0015629 | cellular_component | actin cytoskeleton |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0030240 | biological_process | skeletal muscle thin filament assembly |
| I | 0048741 | biological_process | skeletal muscle fiber development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | ADP402 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue ADP A 402 |
| Chain | Residue |
| A | GLY298 |
| A | TYR302 |
| A | LYS332 |
| A | MG401 |
| A | GLY9 |
| A | SER10 |
| A | GLY11 |
| A | LEU12 |
| A | GLY152 |
| A | ASP153 |
| A | LYS209 |
| A | GLU210 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 801 |
| Chain | Residue |
| C | GLN505 |
| C | ASP522 |
| C | ADP802 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue ADP C 802 |
| Chain | Residue |
| C | GLY381 |
| C | SER382 |
| C | GLY383 |
| C | LEU384 |
| C | LYS386 |
| C | GLN505 |
| C | SER523 |
| C | GLY524 |
| C | ASP525 |
| C | GLU582 |
| C | GLY670 |
| C | THR671 |
| C | TYR674 |
| C | LYS704 |
| C | MG801 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue MG E 1201 |
| Chain | Residue |
| E | GLN877 |
| E | ADP1202 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue ADP E 1202 |
| Chain | Residue |
| E | GLY753 |
| E | SER754 |
| E | LEU756 |
| E | LYS758 |
| E | GLY896 |
| E | ASP897 |
| E | GLU954 |
| E | GLY1042 |
| E | THR1043 |
| E | TYR1046 |
| E | LYS1076 |
| E | MG1201 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG G 1501 |
| Chain | Residue |
| G | LYS1130 |
| G | ADP1502 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue ADP G 1502 |
| Chain | Residue |
| G | GLY1125 |
| G | SER1126 |
| G | GLY1127 |
| G | LEU1128 |
| G | LYS1130 |
| G | GLN1249 |
| G | GLY1268 |
| G | ASP1269 |
| G | GLU1326 |
| G | GLY1414 |
| G | TYR1418 |
| G | LYS1448 |
| G | MG1501 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue MG I 1901 |
| Chain | Residue |
| I | GLY1640 |
| I | ASP1641 |
| I | ADP1902 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue ADP I 1902 |
| Chain | Residue |
| I | GLY1497 |
| I | LEU1500 |
| I | GLY1640 |
| I | ASP1641 |
| I | LYS1697 |
| I | GLU1698 |
| I | GLY1786 |
| I | TYR1790 |
| I | LYS1820 |
| I | MG1901 |
Functional Information from PROSITE/UniProt
| site_id | PS00406 |
| Number of Residues | 11 |
| Details | ACTINS_1 Actins signature 1. YVGDEAQs.KRG |
| Chain | Residue | Details |
| A | TYR49-GLY59 |
| site_id | PS00432 |
| Number of Residues | 9 |
| Details | ACTINS_2 Actins signature 2. WITKqEYDE |
| Chain | Residue | Details |
| A | TRP352-GLU360 |
| site_id | PS01132 |
| Number of Residues | 13 |
| Details | ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR |
| Chain | Residue | Details |
| A | LEU100-ARG112 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | MOD_RES: N-acetylcysteine; in intermediate form => ECO:0000250|UniProtKB:P62737 |
| Chain | Residue | Details |
| A | CYS-4 | |
| C | CYS368 | |
| E | CYS740 | |
| G | CYS1112 | |
| I | CYS1484 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | MOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:456601 |
| Chain | Residue | Details |
| A | ASP-3 | |
| C | ASP369 | |
| E | ASP741 | |
| G | ASP1113 | |
| I | ASP1485 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | MOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134 |
| Chain | Residue | Details |
| A | MET40 | |
| I | MET1531 | |
| A | MET43 | |
| C | MET412 | |
| C | MET415 | |
| E | MET784 | |
| E | MET787 | |
| G | MET1156 | |
| G | MET1159 | |
| I | MET1528 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:12356759, ECO:0007744|PDB:1MDU |
| Chain | Residue | Details |
| A | HIS69 | |
| C | HIS441 | |
| E | HIS813 | |
| G | HIS1185 | |
| I | HIS1557 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | MOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133 |
| Chain | Residue | Details |
| A | LYS80 | |
| C | LYS452 | |
| E | LYS824 | |
| G | LYS1196 | |
| I | LYS1568 |
