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7BS2

Bovine Pancreatic Trypsin with serotonin (Room Temperature)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004175molecular_functionendopeptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006508biological_processproteolysis
A0007586biological_processdigestion
A0008236molecular_functionserine-type peptidase activity
A0046872molecular_functionmetal ion binding
A0097180cellular_componentserine protease inhibitor complex
A0097655molecular_functionserpin family protein binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue CA A 301
ChainResidue
AGLU75
AASN77
AVAL80
AGLU85
AHOH403
AHOH505

site_idAC2
Number of Residues11
Detailsbinding site for residue SRO A 302
ChainResidue
AGLN197
ASER200
ASER207
ASER215
ATRP216
AGLY217
AHOH489
AHOH579
AASP194
ASER195
ACYS196

site_idAC3
Number of Residues6
Detailsbinding site for residue SO4 A 303
ChainResidue
APRO129
ATHR130
ASER131
AGLY151
ALYS209
AGLN211

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC
ChainResidueDetails
AVAL59-CYS64

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV
ChainResidueDetails
AASP194-VAL205

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AHIS63
AASP107
ASER200

site_idSWS_FT_FI2
Number of Residues7
DetailsBINDING:
ChainResidueDetails
AGLU75
AASN77
AVAL80
AGLU85
AASP194
AGLN197
ASER200

227561

PDB entries from 2024-11-20

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