7BR9

Crystal structure of mus musculus IRG1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002760	biological_process	positive regulation of antimicrobial humoral response
A	0005739	cellular_component	mitochondrion
A	0006952	biological_process	defense response
A	0006954	biological_process	inflammatory response
A	0007566	biological_process	embryo implantation
A	0009617	biological_process	response to bacterium
A	0016829	molecular_function	lyase activity
A	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
A	0032480	biological_process	negative regulation of type I interferon production
A	0032496	biological_process	response to lipopolysaccharide
A	0034136	biological_process	negative regulation of toll-like receptor 2 signaling pathway
A	0034144	biological_process	negative regulation of toll-like receptor 4 signaling pathway
A	0035458	biological_process	cellular response to interferon-beta
A	0042803	molecular_function	protein homodimerization activity
A	0045087	biological_process	innate immune response
A	0045824	biological_process	negative regulation of innate immune response
A	0047613	molecular_function	aconitate decarboxylase activity
A	0050728	biological_process	negative regulation of inflammatory response
A	0051607	biological_process	defense response to virus
A	0071219	biological_process	cellular response to molecule of bacterial origin
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071346	biological_process	cellular response to type II interferon
A	0071347	biological_process	cellular response to interleukin-1
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0071393	biological_process	cellular response to progesterone stimulus
A	0072573	biological_process	tolerance induction to lipopolysaccharide
A	2000379	biological_process	positive regulation of reactive oxygen species metabolic process
B	0002760	biological_process	positive regulation of antimicrobial humoral response
B	0005739	cellular_component	mitochondrion
B	0006952	biological_process	defense response
B	0006954	biological_process	inflammatory response
B	0007566	biological_process	embryo implantation
B	0009617	biological_process	response to bacterium
B	0016829	molecular_function	lyase activity
B	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
B	0032480	biological_process	negative regulation of type I interferon production
B	0032496	biological_process	response to lipopolysaccharide
B	0034136	biological_process	negative regulation of toll-like receptor 2 signaling pathway
B	0034144	biological_process	negative regulation of toll-like receptor 4 signaling pathway
B	0035458	biological_process	cellular response to interferon-beta
B	0042803	molecular_function	protein homodimerization activity
B	0045087	biological_process	innate immune response
B	0045824	biological_process	negative regulation of innate immune response
B	0047613	molecular_function	aconitate decarboxylase activity
B	0050728	biological_process	negative regulation of inflammatory response
B	0051607	biological_process	defense response to virus
B	0071219	biological_process	cellular response to molecule of bacterial origin
B	0071222	biological_process	cellular response to lipopolysaccharide
B	0071346	biological_process	cellular response to type II interferon
B	0071347	biological_process	cellular response to interleukin-1
B	0071356	biological_process	cellular response to tumor necrosis factor
B	0071393	biological_process	cellular response to progesterone stimulus
B	0072573	biological_process	tolerance induction to lipopolysaccharide
B	2000379	biological_process	positive regulation of reactive oxygen species metabolic process