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7BPU

Structural and mechanistic insights into the biosynthesis of Digeranylgeranylglyceryl phosphate synthase in membranes

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0004659molecular_functionprenyltransferase activity
A0005886cellular_componentplasma membrane
A0006629biological_processlipid metabolic process
A0006650biological_processglycerophospholipid metabolic process
A0008654biological_processphospholipid biosynthetic process
A0016020cellular_componentmembrane
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0046474biological_processglycerophospholipid biosynthetic process
A0047295molecular_functiongeranylgeranylglycerol-phosphate geranylgeranyltransferase activity
B0000287molecular_functionmagnesium ion binding
B0004659molecular_functionprenyltransferase activity
B0005886cellular_componentplasma membrane
B0006629biological_processlipid metabolic process
B0006650biological_processglycerophospholipid metabolic process
B0008654biological_processphospholipid biosynthetic process
B0016020cellular_componentmembrane
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0046474biological_processglycerophospholipid biosynthetic process
B0047295molecular_functiongeranylgeranylglycerol-phosphate geranylgeranyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues2
Detailsbinding site for residue PO4 A 301
ChainResidue
AARG175
ALYS179

site_idAC2
Number of Residues3
Detailsbinding site for residue PO4 B 301
ChainResidue
BARG175
BLYS179
BLYS266

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues320
DetailsTRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_01286
ChainResidueDetails
AILE21-ILE41
BLEU45-PHE65
BLEU97-ILE117
BILE135-GLY155
BVAL158-VAL178
BLEU204-LEU224
BILE226-MET246
BVAL261-ILE281
ALEU45-PHE65
ALEU97-ILE117
AILE135-GLY155
AVAL158-VAL178
ALEU204-LEU224
AILE226-MET246
AVAL261-ILE281
BILE21-ILE41

238268

PDB entries from 2025-07-02

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