Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7BOP

Crystal Structure of Core-mannan synthase A (CmsA/Ktr4) from Aspergillus fumigatus, Mn/GDP-form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000030	molecular_function	mannosyltransferase activity
A	0006486	biological_process	protein glycosylation
A	0016020	cellular_component	membrane
B	0000030	molecular_function	mannosyltransferase activity
B	0006486	biological_process	protein glycosylation
B	0016020	cellular_component	membrane
C	0000030	molecular_function	mannosyltransferase activity
C	0006486	biological_process	protein glycosylation
C	0016020	cellular_component	membrane
D	0000030	molecular_function	mannosyltransferase activity
D	0006486	biological_process	protein glycosylation
D	0016020	cellular_component	membrane
E	0000030	molecular_function	mannosyltransferase activity
E	0006486	biological_process	protein glycosylation
E	0016020	cellular_component	membrane
F	0000030	molecular_function	mannosyltransferase activity
F	0006486	biological_process	protein glycosylation
F	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MN A 401

Chain	Residue
A	GLU205
A	HIS354
A	GDP402
A	HOH600
A	HOH730

site_id	AC2
Number of Residues	21
Details	binding site for residue GDP A 402

Chain	Residue
A	ASN117
A	ASP118
A	TRP147
A	SER177
A	TYR178
A	MET181
A	GLU205
A	PRO206
A	HIS354
A	MN401
A	HOH546
A	HOH547
A	HOH600
A	HOH604
A	HOH647
A	HOH664
A	HOH730
A	LEU85
A	VAL86
A	ARG87
A	GLU90

site_id	AC3
Number of Residues	5
Details	binding site for residue NA A 403

Chain	Residue
A	ALA63
A	ASN66
A	HOH733
A	HOH797
B	HOH728

site_id	AC4
Number of Residues	5
Details	binding site for residue NA A 404

Chain	Residue
A	THR166
A	LYS169
A	TYR172
A	HOH760
D	HOH626

site_id	AC5
Number of Residues	6
Details	binding site for residue GOL A 405

Chain	Residue
A	ASN264
A	MET265
A	MET266
A	GLY267
A	HOH507
E	PHE33

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL A 406

Chain	Residue
A	ASN263
A	ALA342
A	VAL394
A	HOH784
E	SER28
E	LYS45

site_id	AC7
Number of Residues	4
Details	binding site for residue GOL A 407

Chain	Residue
A	TYR138
A	GLU140
A	ALA194
A	TYR198

site_id	AC8
Number of Residues	4
Details	binding site for residue GOL A 408

Chain	Residue
A	HIS289
A	TRP291
A	HOH508
A	HOH716

site_id	AC9
Number of Residues	5
Details	binding site for residue MN B 401

Chain	Residue
B	GLU205
B	HIS354
B	GDP402
B	HOH537
B	HOH701

site_id	AD1
Number of Residues	20
Details	binding site for residue GDP B 402

Chain	Residue
B	LEU85
B	VAL86
B	ARG87
B	GLU90
B	ASN117
B	ASP118
B	TRP147
B	SER177
B	TYR178
B	MET181
B	GLU205
B	PRO206
B	HIS354
B	MN401
B	HOH518
B	HOH537
B	HOH554
B	HOH606
B	HOH636
B	HOH701

site_id	AD2
Number of Residues	5
Details	binding site for residue NA B 403

Chain	Residue
A	HOH635
B	THR166
B	LYS169
B	TYR172
B	HOH763

site_id	AD3
Number of Residues	6
Details	binding site for residue NA B 404

Chain	Residue
A	HOH729
B	ALA63
B	ASN66
B	HOH748
B	HOH796
B	HOH811

site_id	AD4
Number of Residues	10
Details	binding site for residue GOL B 405

Chain	Residue
F	SER32
F	PHE33
F	LYS45
B	ASN264
B	MET265
B	MET266
B	GLY267
B	HOH501
B	HOH503
F	PRO31

site_id	AD5
Number of Residues	4
Details	binding site for residue GOL B 406

Chain	Residue
B	HIS289
B	TRP291
B	HOH547
B	HOH679

site_id	AD6
Number of Residues	7
Details	binding site for residue GOL B 407

Chain	Residue
B	GLU151
B	ILE153
B	ASN154
B	HOH506
B	HOH662
F	ASN154
F	HOH717

site_id	AD7
Number of Residues	4
Details	binding site for residue GOL B 408

Chain	Residue
B	TYR138
B	GLU140
B	ALA194
B	TYR198

site_id	AD8
Number of Residues	5
Details	binding site for residue MN C 401

Chain	Residue
C	GLU205
C	HIS354
C	GDP402
C	HOH510
C	HOH526

site_id	AD9
Number of Residues	21
Details	binding site for residue GDP C 402

Chain	Residue
C	LEU85
C	VAL86
C	ARG87
C	GLU90
C	ASN117
C	ASP118
C	TRP147
C	TYR172
C	SER177
C	TYR178
C	MET181
C	GLU205
C	PRO206
C	HIS354
C	MN401
C	HOH510
C	HOH526
C	HOH595
C	HOH617
C	HOH668
C	HOH731

site_id	AE1
Number of Residues	5
Details	binding site for residue NA C 403

Chain	Residue
C	ALA63
C	ASN66
C	HOH729
C	HOH778
C	HOH787

site_id	AE2
Number of Residues	4
Details	binding site for residue GOL C 404

Chain	Residue
C	TYR138
C	GLU140
C	ALA194
C	TYR198

site_id	AE3
Number of Residues	6
Details	binding site for residue GOL C 405

Chain	Residue
C	HIS289
C	TRP291
C	HOH502
C	HOH517
C	HOH537
C	HOH613

site_id	AE4
Number of Residues	5
Details	binding site for residue MN D 401

Chain	Residue
D	GLU205
D	HIS354
D	GDP402
D	HOH525
D	HOH664

site_id	AE5
Number of Residues	19
Details	binding site for residue GDP D 402

Chain	Residue
D	LEU85
D	VAL86
D	ARG87
D	GLU90
D	ASN117
D	ASP118
D	TRP147
D	SER177
D	TYR178
D	MET181
D	GLU205
D	PRO206
D	HIS354
D	MN401
D	HOH511
D	HOH525
D	HOH596
D	HOH600
D	HOH664

site_id	AE6
Number of Residues	5
Details	binding site for residue NA D 403

Chain	Residue
D	THR166
D	LYS169
D	TYR172
D	HOH652
D	HOH740

site_id	AE7
Number of Residues	5
Details	binding site for residue NA D 404

Chain	Residue
D	ALA63
D	ASN66
D	HOH640
D	HOH700
D	HOH762

site_id	AE8
Number of Residues	8
Details	binding site for residue GOL D 405

Chain	Residue
C	SER26
C	GLN27
C	SER28
C	LYS45
D	ASN263
D	ALA342
D	VAL394
D	HOH666

site_id	AE9
Number of Residues	6
Details	binding site for residue GOL D 406

Chain	Residue
C	PHE33
D	ASN264
D	MET265
D	MET266
D	GLY267
D	HOH520

site_id	AF1
Number of Residues	5
Details	binding site for residue GOL D 407

Chain	Residue
D	HIS289
D	TRP291
D	HOH503
D	HOH633
D	HOH657

site_id	AF2
Number of Residues	5
Details	binding site for residue MN E 401

Chain	Residue
E	GLU205
E	HIS354
E	GDP402
E	HOH555
E	HOH565

site_id	AF3
Number of Residues	20
Details	binding site for residue GDP E 402

Chain	Residue
E	LEU85
E	VAL86
E	ARG87
E	GLU90
E	ASN117
E	ASP118
E	TRP147
E	TYR172
E	SER177
E	TYR178
E	MET181
E	GLU205
E	PRO206
E	HIS354
E	MN401
E	HOH524
E	HOH555
E	HOH565
E	HOH594
E	HOH599

site_id	AF4
Number of Residues	5
Details	binding site for residue GOL E 403

Chain	Residue
E	GLN171
E	HIS289
E	TRP291
E	HOH508
E	HOH708

site_id	AF5
Number of Residues	4
Details	binding site for residue GOL E 404

Chain	Residue
E	TYR138
E	GLU140
E	ALA194
E	TYR198

site_id	AF6
Number of Residues	6
Details	binding site for residue GOL E 405

Chain	Residue
E	PHE221
E	HIS397
E	HOH519
E	HOH535
E	HOH637
E	HOH726

site_id	AF7
Number of Residues	6
Details	binding site for residue GOL E 406

Chain	Residue
E	SER75
E	ALA76
E	ARG77
E	THR78
E	GLU223
E	HOH601

site_id	AF8
Number of Residues	5
Details	binding site for residue MN F 401

Chain	Residue
F	GLU205
F	HIS354
F	GDP402
F	HOH532
F	HOH568

site_id	AF9
Number of Residues	21
Details	binding site for residue GDP F 402

Chain	Residue
F	LEU85
F	VAL86
F	ARG87
F	GLU90
F	ASN117
F	ASP118
F	TYR172
F	SER177
F	TYR178
F	MET181
F	GLU205
F	PRO206
F	HIS354
F	MN401
F	HOH504
F	HOH532
F	HOH568
F	HOH576
F	HOH580
F	HOH598
F	HOH599

site_id	AG1
Number of Residues	2
Details	binding site for residue GOL F 403

Chain	Residue
F	HIS289
F	TRP291

site_id	AG2
Number of Residues	5
Details	binding site for residue GOL F 404

Chain	Residue
F	TYR138
F	GLU140
F	ALA194
F	TYR198
F	HOH514

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)