7BKA

Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA) from Pseudomonas aeruginosa in complex with DDD01870824

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006633	biological_process	fatty acid biosynthetic process
A	0006636	biological_process	unsaturated fatty acid biosynthetic process
A	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
A	0016829	molecular_function	lyase activity
A	0016853	molecular_function	isomerase activity
A	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
A	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
B	0005737	cellular_component	cytoplasm
B	0006633	biological_process	fatty acid biosynthetic process
B	0006636	biological_process	unsaturated fatty acid biosynthetic process
B	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
B	0016829	molecular_function	lyase activity
B	0016853	molecular_function	isomerase activity
B	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
B	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
C	0005737	cellular_component	cytoplasm
C	0006633	biological_process	fatty acid biosynthetic process
C	0006636	biological_process	unsaturated fatty acid biosynthetic process
C	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
C	0016829	molecular_function	lyase activity
C	0016853	molecular_function	isomerase activity
C	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
C	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
D	0005737	cellular_component	cytoplasm
D	0006633	biological_process	fatty acid biosynthetic process
D	0006636	biological_process	unsaturated fatty acid biosynthetic process
D	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
D	0016829	molecular_function	lyase activity
D	0016853	molecular_function	isomerase activity
D	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
D	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
E	0005737	cellular_component	cytoplasm
E	0006633	biological_process	fatty acid biosynthetic process
E	0006636	biological_process	unsaturated fatty acid biosynthetic process
E	0008693	molecular_function	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
E	0016829	molecular_function	lyase activity
E	0016853	molecular_function	isomerase activity
E	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
E	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue 4JC A 201

Chain	Residue
A	GLN27
A	GLY103
A	ARG104
A	ALA105
A	DMS202
A	HIS70
A	PHE71
A	PRO78
A	GLY79
A	CYS80
A	ASP84
A	TRP87
A	GLN88

---

site_id	AC2
Number of Residues	6
Details	binding site for residue DMS A 202

Chain	Residue
A	MET77
A	ARG104
A	ALA105
A	GLY115
A	PHE171
A	4JC201

---

site_id	AC3
Number of Residues	13
Details	binding site for residue 4JC B 201

Chain	Residue
B	GLN27
B	ASP84
B	TRP87
B	GLN88
B	GLY103
B	ARG104
B	ALA105
B	DMS202
C	HIS70
C	PHE71
C	PRO78
C	GLY79
C	CYS80

---

site_id	AC4
Number of Residues	6
Details	binding site for residue DMS B 202

Chain	Residue
B	ARG104
B	ALA105
B	4JC201
C	MET77
C	PHE113
C	GLY115

---

site_id	AC5
Number of Residues	12
Details	binding site for residue 4JC C 201

Chain	Residue
B	HIS70
B	PHE71
B	PRO78
B	GLY79
B	CYS80
C	GLN27
C	ASP84
C	TRP87
C	GLN88
C	GLY103
C	ALA105
C	DMS202

---

site_id	AC6
Number of Residues	5
Details	binding site for residue DMS C 202

Chain	Residue
B	MET77
B	GLY115
C	ARG104
C	ALA105
C	4JC201

---

site_id	AC7
Number of Residues	13
Details	binding site for residue 4JC D 201

Chain	Residue
D	GLN27
D	ASP84
D	TRP87
D	GLN88
D	GLY103
D	ARG104
D	ALA105
D	DMS202
E	HIS70
E	PHE71
E	PRO78
E	GLY79
E	CYS80

---

site_id	AC8
Number of Residues	6
Details	binding site for residue DMS D 202

Chain	Residue
D	ARG104
D	ALA105
D	PHE171
D	4JC201
E	MET77
E	GLY115

---

site_id	AC9
Number of Residues	13
Details	binding site for residue 4JC E 201

Chain	Residue
D	HIS70
D	PHE71
D	PRO78
D	GLY79
D	CYS80
E	GLN27
E	ASP84
E	TRP87
E	GLN88
E	GLY103
E	ARG104
E	ALA105
E	DMS202

---

site_id	AD1
Number of Residues	6
Details	binding site for residue DMS E 202

Chain	Residue
D	MET77
D	PHE113
D	GLY115
E	ARG104
E	ALA105
E	4JC201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	HIS70
B	HIS70
C	HIS70
D	HIS70
E	HIS70

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