7BKA
Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA) from Pseudomonas aeruginosa in complex with DDD01870824
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| A | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| A | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| B | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| B | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| C | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| C | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| D | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| D | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006633 | biological_process | fatty acid biosynthetic process |
| E | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| E | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| E | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 4JC A 201 |
| Chain | Residue |
| A | GLN27 |
| A | GLY103 |
| A | ARG104 |
| A | ALA105 |
| A | DMS202 |
| A | HIS70 |
| A | PHE71 |
| A | PRO78 |
| A | GLY79 |
| A | CYS80 |
| A | ASP84 |
| A | TRP87 |
| A | GLN88 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 202 |
| Chain | Residue |
| A | MET77 |
| A | ARG104 |
| A | ALA105 |
| A | GLY115 |
| A | PHE171 |
| A | 4JC201 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue 4JC B 201 |
| Chain | Residue |
| B | GLN27 |
| B | ASP84 |
| B | TRP87 |
| B | GLN88 |
| B | GLY103 |
| B | ARG104 |
| B | ALA105 |
| B | DMS202 |
| C | HIS70 |
| C | PHE71 |
| C | PRO78 |
| C | GLY79 |
| C | CYS80 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 202 |
| Chain | Residue |
| B | ARG104 |
| B | ALA105 |
| B | 4JC201 |
| C | MET77 |
| C | PHE113 |
| C | GLY115 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue 4JC C 201 |
| Chain | Residue |
| B | HIS70 |
| B | PHE71 |
| B | PRO78 |
| B | GLY79 |
| B | CYS80 |
| C | GLN27 |
| C | ASP84 |
| C | TRP87 |
| C | GLN88 |
| C | GLY103 |
| C | ALA105 |
| C | DMS202 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 202 |
| Chain | Residue |
| B | MET77 |
| B | GLY115 |
| C | ARG104 |
| C | ALA105 |
| C | 4JC201 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue 4JC D 201 |
| Chain | Residue |
| D | GLN27 |
| D | ASP84 |
| D | TRP87 |
| D | GLN88 |
| D | GLY103 |
| D | ARG104 |
| D | ALA105 |
| D | DMS202 |
| E | HIS70 |
| E | PHE71 |
| E | PRO78 |
| E | GLY79 |
| E | CYS80 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue DMS D 202 |
| Chain | Residue |
| D | ARG104 |
| D | ALA105 |
| D | PHE171 |
| D | 4JC201 |
| E | MET77 |
| E | GLY115 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for residue 4JC E 201 |
| Chain | Residue |
| D | HIS70 |
| D | PHE71 |
| D | PRO78 |
| D | GLY79 |
| D | CYS80 |
| E | GLN27 |
| E | ASP84 |
| E | TRP87 |
| E | GLN88 |
| E | GLY103 |
| E | ARG104 |
| E | ALA105 |
| E | DMS202 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue DMS E 202 |
| Chain | Residue |
| D | MET77 |
| D | PHE113 |
| D | GLY115 |
| E | ARG104 |
| E | ALA105 |
| E | 4JC201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
