7BIV

Inhibitor of MDM2-p53 Interaction

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue DMS A 201

Chain	Residue
A	LYS31
A	ALA70
A	GLN71
A	GLN72
A	HIS73
A	HOH359

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site_id	AC2
Number of Residues	2
Details	binding site for residue DMS A 202

Chain	Residue
A	ASP46
A	THR47

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site_id	AC3
Number of Residues	5
Details	binding site for residue EDO A 203

Chain	Residue
A	ASP80
A	LEU81
A	HOH308
A	HOH309
A	LYS64

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site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 204

Chain	Residue
A	ARG97
A	ARG97
A	HOH302
A	HOH302
A	HOH303
A	HOH337

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site_id	AC5
Number of Residues	8
Details	binding site for residue SO4 A 205

Chain	Residue
A	LEU27
A	LEU27
A	VAL28
A	VAL28
A	ARG29
A	ARG29
A	HOH339
A	HOH339

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site_id	AC6
Number of Residues	14
Details	binding site for residue TUW A 206

Chain	Residue
A	PRO32
A	LEU33
A	LEU54
A	PHE55
A	GLY58
A	GLN59
A	ILE61
A	GLN72
A	ILE74
A	VAL93
A	HIS96
A	TYR100
A	HOH304
A	HOH345

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