7BIS

Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA)from Pseudomonas aeruginosa in complex with DDD00082063

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006633	biological_process	fatty acid biosynthetic process
A	0006636	biological_process	unsaturated fatty acid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016853	molecular_function	isomerase activity
A	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
A	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
B	0005737	cellular_component	cytoplasm
B	0006633	biological_process	fatty acid biosynthetic process
B	0006636	biological_process	unsaturated fatty acid biosynthetic process
B	0016829	molecular_function	lyase activity
B	0016853	molecular_function	isomerase activity
B	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
B	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
C	0005737	cellular_component	cytoplasm
C	0006633	biological_process	fatty acid biosynthetic process
C	0006636	biological_process	unsaturated fatty acid biosynthetic process
C	0016829	molecular_function	lyase activity
C	0016853	molecular_function	isomerase activity
C	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
C	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
D	0005737	cellular_component	cytoplasm
D	0006633	biological_process	fatty acid biosynthetic process
D	0006636	biological_process	unsaturated fatty acid biosynthetic process
D	0016829	molecular_function	lyase activity
D	0016853	molecular_function	isomerase activity
D	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
D	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
E	0005737	cellular_component	cytoplasm
E	0006633	biological_process	fatty acid biosynthetic process
E	0006636	biological_process	unsaturated fatty acid biosynthetic process
E	0016829	molecular_function	lyase activity
E	0016853	molecular_function	isomerase activity
E	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
E	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue TZQ A 201

Chain	Residue
A	HIS70
A	TYR155
A	HOH303
A	MET77
A	PRO78
A	GLY79
A	ARG104
A	ALA105
A	PHE114
A	GLY115
A	GLN116

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site_id	AC2
Number of Residues	9
Details	binding site for residue TZQ B 201

Chain	Residue
B	ARG104
B	ALA105
C	HIS70
C	MET77
C	PRO78
C	GLY79
C	PHE114
C	GLY115
C	GLN116

---

site_id	AC3
Number of Residues	10
Details	binding site for residue TZQ C 201

Chain	Residue
B	HIS70
B	MET77
B	PRO78
B	GLY79
B	PHE114
B	GLY115
C	ARG104
C	ALA105
C	PHE165
C	HOH301

---

site_id	AC4
Number of Residues	10
Details	binding site for residue TZQ E 201

Chain	Residue
D	ARG104
D	ALA105
D	HOH201
E	HIS70
E	MET77
E	PRO78
E	GLY79
E	GLY115
E	GLN116
E	TYR155

---

site_id	AC5
Number of Residues	9
Details	binding site for residue TZQ E 202

Chain	Residue
D	HIS70
D	MET77
D	PRO78
D	GLY79
D	PHE113
D	PHE114
D	GLY115
E	ARG104
E	ALA105

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	HIS70
B	HIS70
C	HIS70
D	HIS70
E	HIS70

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