7BHJ

Crystal structure of 3-hydroxydecanoyl-acyl carrier protein dehydratase (FabA) from Pseudomonas aeruginosa in complex with DDD00084774

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0006636	biological_process	unsaturated fatty acid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016853	molecular_function	isomerase activity
A	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
A	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0006636	biological_process	unsaturated fatty acid biosynthetic process
B	0016829	molecular_function	lyase activity
B	0016853	molecular_function	isomerase activity
B	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
B	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0006636	biological_process	unsaturated fatty acid biosynthetic process
C	0016829	molecular_function	lyase activity
C	0016853	molecular_function	isomerase activity
C	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
C	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0006636	biological_process	unsaturated fatty acid biosynthetic process
D	0016829	molecular_function	lyase activity
D	0016853	molecular_function	isomerase activity
D	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
D	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006629	biological_process	lipid metabolic process
E	0006631	biological_process	fatty acid metabolic process
E	0006633	biological_process	fatty acid biosynthetic process
E	0006636	biological_process	unsaturated fatty acid biosynthetic process
E	0016829	molecular_function	lyase activity
E	0016853	molecular_function	isomerase activity
E	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
E	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue TQH B 201

Chain	Residue
B	GLN27
C	PRO78
C	GLY79
C	GLY115
C	HOH302
B	LEU28
B	GLN88
B	GLY103
B	ALA105
B	HOH301
B	HOH302
C	HIS70
C	MET77

---

site_id	AC2
Number of Residues	12
Details	binding site for residue TQH C 201

Chain	Residue
B	HIS70
B	MET77
B	GLY79
B	PHE113
B	GLY115
C	GLN27
C	GLN88
C	GLY103
C	ALA105
C	PHE171
C	HOH301
C	HOH304

---

site_id	AC3
Number of Residues	12
Details	binding site for residue TQH D 201

Chain	Residue
D	GLN27
D	LEU28
D	GLN88
D	GLY103
D	ALA105
D	HOH301
D	HOH304
E	HIS70
E	MET77
E	PRO78
E	GLY79
E	GLY115

---

site_id	AC4
Number of Residues	16
Details	binding site for residue TQH E 201

Chain	Residue
D	HIS70
D	PHE71
D	MET77
D	GLY79
D	PHE113
D	GLY115
E	GLN27
E	LEU28
E	GLN88
E	GLY91
E	GLY103
E	ARG104
E	ALA105
E	PHE171
E	HOH301
E	HOH305

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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