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7BER

SFX structure of the MyD88 TIR domain higher-order assembly (solved, rebuilt and refined using an identical protocol to the MicroED structure of the MyD88 TIR domain higher-order assembly)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002755biological_processMyD88-dependent toll-like receptor signaling pathway
A0007165biological_processsignal transduction
A0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
A0070976molecular_functionTIR domain binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues134
DetailsDomain: {"description":"TIR","evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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