7B4J
Thermostable omega transaminase PjTA-R6 variant W58M/F86L/R417L engineered for asymmetric synthesis of enantiopure bulky amines
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004015 | molecular_function | adenosylmethionine-8-amino-7-oxononanoate transaminase activity |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009102 | biological_process | biotin biosynthetic process |
| A | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0004015 | molecular_function | adenosylmethionine-8-amino-7-oxononanoate transaminase activity |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0009102 | biological_process | biotin biosynthetic process |
| B | 0009448 | biological_process | gamma-aminobutyric acid metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue PMP A 1501 |
| Chain | Residue |
| A | SER117 |
| A | ILE261 |
| A | LYS287 |
| A | HOH1617 |
| A | HOH1622 |
| B | PHE323 |
| B | THR324 |
| B | HOH1315 |
| A | GLY118 |
| A | SER119 |
| A | TYR151 |
| A | HIS152 |
| A | GLY153 |
| A | GLU225 |
| A | ASP258 |
| A | VAL260 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SIN B 1101 |
| Chain | Residue |
| B | GLN38 |
| B | TYR41 |
| B | TYR43 |
| B | HOH1232 |
| B | HOH1281 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue PMP B 1102 |
| Chain | Residue |
| A | PHE323 |
| A | THR324 |
| B | SER117 |
| B | GLY118 |
| B | SER119 |
| B | TYR151 |
| B | HIS152 |
| B | GLU225 |
| B | ASP258 |
| B | VAL260 |
| B | ILE261 |
| B | LYS287 |
| B | HOH1204 |
| B | HOH1285 |
| B | HOH1300 |
| B | HOH1305 |
Functional Information from PROSITE/UniProt
| site_id | PS00600 |
| Number of Residues | 38 |
| Details | AA_TRANSFER_CLASS_3 Aminotransferases class-III pyridoxal-phosphate attachment site. VIaDEVic.GFgRtGqmfgsqtfgiqp....DIMvlSKqlsSS |
| Chain | Residue | Details |
| A | VAL255-SER292 |
