7B36
MST4 in complex with compound G-5555
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 701 |
| Chain | Residue |
| A | LYS40 |
| A | HOH809 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 702 |
| Chain | Residue |
| A | PHE184 |
| A | SER220 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue 59T A 703 |
| Chain | Residue |
| A | LEU74 |
| A | MET99 |
| A | GLU100 |
| A | LEU102 |
| A | ALA148 |
| A | ASN149 |
| A | LEU151 |
| A | ASP162 |
| A | HOH817 |
| A | HOH829 |
| A | VAL38 |
| A | ALA51 |
| A | LYS53 |
| A | GLU70 |
| A | ILE71 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 704 |
| Chain | Residue |
| A | LEU110 |
| A | LEU287 |
| A | ARG290 |
| A | PHE291 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | PHE184 |
| C | PRO217 |
| C | SER220 |
| C | HOH602 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue 59T C 502 |
| Chain | Residue |
| C | VAL38 |
| C | ALA51 |
| C | LYS53 |
| C | ILE71 |
| C | LEU74 |
| C | ILE97 |
| C | MET99 |
| C | GLU100 |
| C | LEU102 |
| C | ALA148 |
| C | ASN149 |
| C | LEU151 |
| C | ASP162 |
| C | HOH606 |
| C | HOH613 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGEVFkGidnrtqqv..........VAIK |
| Chain | Residue | Details |
| A | ILE30-LYS53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29232556","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
