Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7B2N

Crystal structure of Chlamydomonas reinhardtii chloroplastic Fructose bisphosphate aldolase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004332	molecular_function	fructose-bisphosphate aldolase activity
A	0006096	biological_process	glycolytic process
A	0009507	cellular_component	chloroplast
A	0016829	molecular_function	lyase activity
B	0004332	molecular_function	fructose-bisphosphate aldolase activity
B	0006096	biological_process	glycolytic process
B	0009507	cellular_component	chloroplast
B	0016829	molecular_function	lyase activity
C	0004332	molecular_function	fructose-bisphosphate aldolase activity
C	0006096	biological_process	glycolytic process
C	0009507	cellular_component	chloroplast
C	0016829	molecular_function	lyase activity
D	0004332	molecular_function	fructose-bisphosphate aldolase activity
D	0006096	biological_process	glycolytic process
D	0009507	cellular_component	chloroplast
D	0016829	molecular_function	lyase activity
E	0004332	molecular_function	fructose-bisphosphate aldolase activity
E	0006096	biological_process	glycolytic process
E	0009507	cellular_component	chloroplast
E	0016829	molecular_function	lyase activity
F	0004332	molecular_function	fructose-bisphosphate aldolase activity
F	0006096	biological_process	glycolytic process
F	0009507	cellular_component	chloroplast
F	0016829	molecular_function	lyase activity
G	0004332	molecular_function	fructose-bisphosphate aldolase activity
G	0006096	biological_process	glycolytic process
G	0009507	cellular_component	chloroplast
G	0016829	molecular_function	lyase activity
H	0004332	molecular_function	fructose-bisphosphate aldolase activity
H	0006096	biological_process	glycolytic process
H	0009507	cellular_component	chloroplast
H	0016829	molecular_function	lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SO4 A 401

Chain	Residue
A	SER54
A	THR57
A	LYS125

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 402

Chain	Residue
A	PRO172
A	GLY211
A	GLU212
A	HIS213
A	HOH546

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 403

Chain	Residue
A	HOH505
H	ARG181
A	ARG181

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 404

Chain	Residue
A	LEU219
A	LYS271
A	ARG275

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 B 401

Chain	Residue
B	LYS44
B	ASN308
B	HIS311
B	HOH592

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 B 402

Chain	Residue
B	ARG181
B	HOH506
B	HOH523
D	ARG181

site_id	AC7
Number of Residues	7
Details	binding site for residue SO4 B 403

Chain	Residue
B	PRO172
B	GLY211
B	GLU212
B	HIS213
B	HOH510
B	HOH570
B	HOH605

site_id	AC8
Number of Residues	6
Details	binding site for residue SO4 B 404

Chain	Residue
B	SER288
B	GLY289
B	ALA317
B	ARG318
B	ALA319
B	HOH519

site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 B 405

Chain	Residue
B	ASP52
B	LYS164
B	ALA317
B	HOH502
B	HOH519

site_id	AD1
Number of Residues	1
Details	binding site for residue CL B 406

Chain	Residue
B	ASP214

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 C 401

Chain	Residue
C	HIS213
C	ASP214
C	ARG217

site_id	AD3
Number of Residues	6
Details	binding site for residue SO4 C 402

Chain	Residue
C	ILE171
C	PRO172
C	ASP210
C	GLY211
C	GLU212
C	HIS213

site_id	AD4
Number of Residues	6
Details	binding site for residue SO4 C 403

Chain	Residue
C	ASP52
C	LYS164
C	HOH502
C	HOH503
C	HOH504
C	HOH515

site_id	AD5
Number of Residues	6
Details	binding site for residue SO4 C 404

Chain	Residue
C	SER288
C	GLY289
C	ALA317
C	ARG318
C	ALA319
C	HOH515

site_id	AD6
Number of Residues	2
Details	binding site for residue SO4 C 405

Chain	Residue
C	ARG181
G	ARG181

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 D 401

Chain	Residue
D	GLU71
D	HOH501
D	HOH543

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 D 402

Chain	Residue
D	PRO172
D	GLY211
D	GLU212
D	HIS213

site_id	AD9
Number of Residues	9
Details	binding site for residue SO4 D 403

Chain	Residue
D	ALA50
D	ASP52
D	LYS164
D	ALA317
D	HOH503
D	HOH508
D	HOH517
D	HOH536
D	HOH545

site_id	AE1
Number of Residues	8
Details	binding site for residue SO4 D 404

Chain	Residue
D	SER288
D	GLY289
D	TYR316
D	ALA317
D	ARG318
D	ALA319
D	HOH503
D	HOH517

site_id	AE2
Number of Residues	3
Details	binding site for residue SO4 E 401

Chain	Residue
E	ARG181
E	HOH513
F	ARG181

site_id	AE3
Number of Residues	6
Details	binding site for residue SO4 E 402

Chain	Residue
E	ILE171
E	PRO172
E	ASP210
E	GLY211
E	GLU212
E	HIS213

site_id	AE4
Number of Residues	3
Details	binding site for residue SO4 F 401

Chain	Residue
F	HOH508
F	LYS271
F	ARG275

site_id	AE5
Number of Residues	6
Details	binding site for residue SO4 F 402

Chain	Residue
F	PRO172
F	ASP210
F	GLY211
F	GLU212
F	HIS213
F	HOH522

site_id	AE6
Number of Residues	6
Details	binding site for residue SO4 F 403

Chain	Residue
F	LYS44
F	HIS311
F	GLN353
F	GLN354
F	HOH509
F	HOH511

site_id	AE7
Number of Residues	4
Details	binding site for residue SO4 F 404

Chain	Residue
F	HIS213
F	ASP214
F	ARG217
F	HOH506

site_id	AE8
Number of Residues	8
Details	binding site for residue SO4 F 405

Chain	Residue
F	SER288
F	GLY289
F	SER315
F	TYR316
F	ALA317
F	ARG318
F	HOH501
F	HOH504

site_id	AE9
Number of Residues	4
Details	binding site for residue SO4 G 401

Chain	Residue
G	LYS44
G	TRP310
G	HIS311
G	GLN353

site_id	AF1
Number of Residues	6
Details	binding site for residue SO4 G 402

Chain	Residue
G	SER288
G	GLY289
G	TYR316
G	ALA317
G	ARG318
G	ALA319

site_id	AF2
Number of Residues	6
Details	binding site for residue SO4 G 403

Chain	Residue
G	PRO172
G	ASP210
G	GLY211
G	GLU212
G	HIS213
G	HOH506

site_id	AF3
Number of Residues	4
Details	binding site for residue SO4 H 401

Chain	Residue
H	PRO172
H	GLY211
H	GLU212
H	HIS213

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	GLU204
B	GLU204
C	GLU204
D	GLU204
E	GLU204
F	GLU204
G	GLU204
H	GLU204

site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Schiff-base intermediate with dihydroxyacetone-P => ECO:0000250

Chain	Residue	Details
A	LYS246
B	LYS246
C	LYS246
D	LYS246
E	LYS246
F	LYS246
G	LYS246
H	LYS246

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG74
E	LYS164
F	ARG74
F	LYS164
G	ARG74
G	LYS164
H	ARG74
H	LYS164
A	LYS164
B	ARG74
B	LYS164
C	ARG74
C	LYS164
D	ARG74
D	LYS164
E	ARG74

site_id	SWS_FT_FI4
Number of Residues	8
Details	SITE: Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate => ECO:0000250

Chain	Residue	Details
A	TYR377
B	TYR377
C	TYR377
D	TYR377
E	TYR377
F	TYR377
G	TYR377
H	TYR377

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)