7B03
Cryo-EM structure of the green-light absorbing proteorhodopsin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0007602 | biological_process | phototransduction |
| A | 0009881 | molecular_function | photoreceptor activity |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0007602 | biological_process | phototransduction |
| B | 0009881 | molecular_function | photoreceptor activity |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0007602 | biological_process | phototransduction |
| C | 0009881 | molecular_function | photoreceptor activity |
| C | 0016020 | cellular_component | membrane |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0007602 | biological_process | phototransduction |
| D | 0009881 | molecular_function | photoreceptor activity |
| D | 0016020 | cellular_component | membrane |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| E | 0005216 | molecular_function | monoatomic ion channel activity |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0006811 | biological_process | monoatomic ion transport |
| E | 0007602 | biological_process | phototransduction |
| E | 0009881 | molecular_function | photoreceptor activity |
| E | 0016020 | cellular_component | membrane |
| E | 0034220 | biological_process | monoatomic ion transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00950 |
| Number of Residues | 13 |
| Details | BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYiDWlLTVPLLI |
| Chain | Residue | Details |
| A | ARG95-ILE107 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 115 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:34226545 |
| Chain | Residue | Details |
| A | ALA19-TYR29 | |
| C | GLY88-SER90 | |
| C | GLY145-MET147 | |
| C | TYR209-LEU218 | |
| D | ALA19-TYR29 | |
| D | GLY88-SER90 | |
| D | GLY145-MET147 | |
| D | TYR209-LEU218 | |
| E | ALA19-TYR29 | |
| E | GLY88-SER90 | |
| E | GLY145-MET147 | |
| A | GLY88-SER90 | |
| E | TYR209-LEU218 | |
| A | GLY145-MET147 | |
| A | TYR209-LEU218 | |
| B | ALA19-TYR29 | |
| B | GLY88-SER90 | |
| B | GLY145-MET147 | |
| B | TYR209-LEU218 | |
| C | ALA19-TYR29 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 930 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:34226545 |
| Chain | Residue | Details |
| A | THR30-ASP53 | |
| B | PRO91-THR118 | |
| B | GLY122-ALA144 | |
| B | ALA148-ASN177 | |
| B | PRO181-GLY208 | |
| B | ASN219-ASN249 | |
| C | THR30-ASP53 | |
| C | TRP59-THR87 | |
| C | PRO91-THR118 | |
| C | GLY122-ALA144 | |
| C | ALA148-ASN177 | |
| A | TRP59-THR87 | |
| C | PRO181-GLY208 | |
| C | ASN219-ASN249 | |
| D | THR30-ASP53 | |
| D | TRP59-THR87 | |
| D | PRO91-THR118 | |
| D | GLY122-ALA144 | |
| D | ALA148-ASN177 | |
| D | PRO181-GLY208 | |
| D | ASN219-ASN249 | |
| E | THR30-ASP53 | |
| A | PRO91-THR118 | |
| E | TRP59-THR87 | |
| E | PRO91-THR118 | |
| E | GLY122-ALA144 | |
| E | ALA148-ASN177 | |
| E | PRO181-GLY208 | |
| E | ASN219-ASN249 | |
| A | GLY122-ALA144 | |
| A | ALA148-ASN177 | |
| A | PRO181-GLY208 | |
| A | ASN219-ASN249 | |
| B | THR30-ASP53 | |
| B | TRP59-THR87 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 45 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:34226545 |
| Chain | Residue | Details |
| A | ARG54-LYS58 | |
| C | ASN119-ALA121 | |
| C | THR178-SER180 | |
| C | ALA250 | |
| D | ARG54-LYS58 | |
| D | ASN119-ALA121 | |
| D | THR178-SER180 | |
| D | ALA250 | |
| E | ARG54-LYS58 | |
| E | ASN119-ALA121 | |
| E | THR178-SER180 | |
| A | ASN119-ALA121 | |
| E | ALA250 | |
| A | THR178-SER180 | |
| A | ALA250 | |
| B | ARG54-LYS58 | |
| B | ASN119-ALA121 | |
| B | THR178-SER180 | |
| B | ALA250 | |
| C | ARG54-LYS58 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | SITE: Primary proton acceptor => ECO:0000255|PIRSR:PIRSR038142-1, ECO:0000305|PubMed:34226545 |
| Chain | Residue | Details |
| A | ASP98 | |
| B | ASP98 | |
| C | ASP98 | |
| D | ASP98 | |
| E | ASP98 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | SITE: Responsible for spectral tuning => ECO:0000255|PIRSR:PIRSR038142-1 |
| Chain | Residue | Details |
| A | LEU106 | |
| B | LEU106 | |
| C | LEU106 | |
| D | LEU106 | |
| E | LEU106 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | SITE: Primary proton donor => ECO:0000255|PIRSR:PIRSR038142-1, ECO:0000305|PubMed:34226545 |
| Chain | Residue | Details |
| A | GLU109 | |
| B | GLU109 | |
| C | GLU109 | |
| D | GLU109 | |
| E | GLU109 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | SITE: Proton release group => ECO:0000305|PubMed:34226545 |
| Chain | Residue | Details |
| A | GLU143 | |
| B | GLU143 | |
| C | GLU143 | |
| D | GLU143 | |
| E | GLU143 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 5 |
| Details | MOD_RES: N6-(retinylidene)lysine => ECO:0000269|PubMed:34226545, ECO:0007744|PDB:7B03 |
| Chain | Residue | Details |
| A | LYS232 | |
| B | LYS232 | |
| C | LYS232 | |
| D | LYS232 | |
| E | LYS232 |
