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7AXD

Crystal structure of the hPXR-LBD in complex with fipronil

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue S6W A 501
ChainResidue
AMET243
ATYR306
AMET323
AHIS407
AIPA504
AIPA505
AMET246
ASER247
APHE251
APHE281
ACYS284
AGLN285
APHE288
ATRP299

site_idAC2
Number of Residues1
Detailsbinding site for residue IPA A 502
ChainResidue
ATRP223

site_idAC3
Number of Residues1
Detailsbinding site for residue IPA A 504
ChainResidue
AS6W501

site_idAC4
Number of Residues4
Detailsbinding site for residue IPA A 505
ChainResidue
ALEU209
AMET243
AMET323
AS6W501

site_idAC5
Number of Residues6
Detailsbinding site for residue IPA A 506
ChainResidue
ALEU335
AGLU337
ATYR340
AARG387
AHOH604
AHOH623

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13
ChainResidueDetails
ASER247
AGLN285
AHIS407

229183

PDB entries from 2024-12-18

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