7AXB

Crystal structure of the hPXR-LBD in complex with endosulfan

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MPD A 501

Chain	Residue
A	GLU337
A	ARG387
A	HOH619
A	HOH634

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site_id	AC2
Number of Residues	7
Details	binding site for residue S68 A 502

Chain	Residue
A	MET323
A	HIS327
A	SER247
A	GLN285
A	PHE288
A	TRP299
A	TYR306

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site_id	AC3
Number of Residues	1
Details	binding site for residue GOL A 504

Chain	Residue
A	HIS407

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13

Chain	Residue	Details
A	SER247
A	GLN285
A	HIS407

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