7AX9

Crystal structure of the hPXR-LBD in complex with cis-chlordane

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue S6H A 501

Chain	Residue
A	LEU209
A	MET243
A	MET246
A	SER247
A	CYS284
A	GLN285
A	PHE288
A	TRP299
A	MET323

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site_id	AC2
Number of Residues	2
Details	binding site for residue IPA A 502

Chain	Residue
A	GLU337
A	TYR340

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site_id	AC3
Number of Residues	1
Details	binding site for residue IPA A 503

Chain	Residue
A	LYS160

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site_id	AC4
Number of Residues	1
Details	binding site for residue GOL A 505

Chain	Residue
A	HIS407

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12578355","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1M13","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"source":"PubMed","id":"26534988","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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