7AX3

CryoEM structure of the super-constricted two-start dynamin 1 filament

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003723	molecular_function	RNA binding
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
A	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
A	0005737	cellular_component	cytoplasm
A	0005874	cellular_component	microtubule
A	0005886	cellular_component	plasma membrane
A	0005905	cellular_component	clathrin-coated pit
A	0006897	biological_process	endocytosis
A	0006898	biological_process	receptor-mediated endocytosis
A	0007032	biological_process	endosome organization
A	0008017	molecular_function	microtubule binding
A	0016020	cellular_component	membrane
A	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
A	0016787	molecular_function	hydrolase activity
A	0019003	molecular_function	GDP binding
A	0019901	molecular_function	protein kinase binding
A	0030139	cellular_component	endocytic vesicle
A	0031410	cellular_component	cytoplasmic vesicle
A	0042583	cellular_component	chromaffin granule
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0045202	cellular_component	synapse
A	0051260	biological_process	protein homooligomerization
A	0051289	biological_process	protein homotetramerization
A	0070062	cellular_component	extracellular exosome
A	0097494	biological_process	regulation of vesicle size
A	0098793	cellular_component	presynapse
A	0099049	biological_process	clathrin coat assembly involved in endocytosis
A	0099050	biological_process	vesicle scission
A2	0000166	molecular_function	nucleotide binding
A2	0003723	molecular_function	RNA binding
A2	0003924	molecular_function	GTPase activity
A2	0005515	molecular_function	protein binding
A2	0005525	molecular_function	GTP binding
A2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
A2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
A2	0005737	cellular_component	cytoplasm
A2	0005874	cellular_component	microtubule
A2	0005886	cellular_component	plasma membrane
A2	0005905	cellular_component	clathrin-coated pit
A2	0006897	biological_process	endocytosis
A2	0006898	biological_process	receptor-mediated endocytosis
A2	0007032	biological_process	endosome organization
A2	0008017	molecular_function	microtubule binding
A2	0016020	cellular_component	membrane
A2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
A2	0016787	molecular_function	hydrolase activity
A2	0019003	molecular_function	GDP binding
A2	0019901	molecular_function	protein kinase binding
A2	0030139	cellular_component	endocytic vesicle
A2	0031410	cellular_component	cytoplasmic vesicle
A2	0042583	cellular_component	chromaffin granule
A2	0042802	molecular_function	identical protein binding
A2	0042803	molecular_function	protein homodimerization activity
A2	0045202	cellular_component	synapse
A2	0051260	biological_process	protein homooligomerization
A2	0051289	biological_process	protein homotetramerization
A2	0070062	cellular_component	extracellular exosome
A2	0097494	biological_process	regulation of vesicle size
A2	0098793	cellular_component	presynapse
A2	0099049	biological_process	clathrin coat assembly involved in endocytosis
A2	0099050	biological_process	vesicle scission
B	0000166	molecular_function	nucleotide binding
B	0003723	molecular_function	RNA binding
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
B	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
B	0005737	cellular_component	cytoplasm
B	0005874	cellular_component	microtubule
B	0005886	cellular_component	plasma membrane
B	0005905	cellular_component	clathrin-coated pit
B	0006897	biological_process	endocytosis
B	0006898	biological_process	receptor-mediated endocytosis
B	0007032	biological_process	endosome organization
B	0008017	molecular_function	microtubule binding
B	0016020	cellular_component	membrane
B	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
B	0016787	molecular_function	hydrolase activity
B	0019003	molecular_function	GDP binding
B	0019901	molecular_function	protein kinase binding
B	0030139	cellular_component	endocytic vesicle
B	0031410	cellular_component	cytoplasmic vesicle
B	0042583	cellular_component	chromaffin granule
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0045202	cellular_component	synapse
B	0051260	biological_process	protein homooligomerization
B	0051289	biological_process	protein homotetramerization
B	0070062	cellular_component	extracellular exosome
B	0097494	biological_process	regulation of vesicle size
B	0098793	cellular_component	presynapse
B	0099049	biological_process	clathrin coat assembly involved in endocytosis
B	0099050	biological_process	vesicle scission
B2	0000166	molecular_function	nucleotide binding
B2	0003723	molecular_function	RNA binding
B2	0003924	molecular_function	GTPase activity
B2	0005515	molecular_function	protein binding
B2	0005525	molecular_function	GTP binding
B2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
B2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
B2	0005737	cellular_component	cytoplasm
B2	0005874	cellular_component	microtubule
B2	0005886	cellular_component	plasma membrane
B2	0005905	cellular_component	clathrin-coated pit
B2	0006897	biological_process	endocytosis
B2	0006898	biological_process	receptor-mediated endocytosis
B2	0007032	biological_process	endosome organization
B2	0008017	molecular_function	microtubule binding
B2	0016020	cellular_component	membrane
B2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
B2	0016787	molecular_function	hydrolase activity
B2	0019003	molecular_function	GDP binding
B2	0019901	molecular_function	protein kinase binding
B2	0030139	cellular_component	endocytic vesicle
B2	0031410	cellular_component	cytoplasmic vesicle
B2	0042583	cellular_component	chromaffin granule
B2	0042802	molecular_function	identical protein binding
B2	0042803	molecular_function	protein homodimerization activity
B2	0045202	cellular_component	synapse
B2	0051260	biological_process	protein homooligomerization
B2	0051289	biological_process	protein homotetramerization
B2	0070062	cellular_component	extracellular exosome
B2	0097494	biological_process	regulation of vesicle size
B2	0098793	cellular_component	presynapse
B2	0099049	biological_process	clathrin coat assembly involved in endocytosis
B2	0099050	biological_process	vesicle scission
C	0000166	molecular_function	nucleotide binding
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
C	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
C	0005737	cellular_component	cytoplasm
C	0005874	cellular_component	microtubule
C	0005886	cellular_component	plasma membrane
C	0005905	cellular_component	clathrin-coated pit
C	0006897	biological_process	endocytosis
C	0006898	biological_process	receptor-mediated endocytosis
C	0007032	biological_process	endosome organization
C	0008017	molecular_function	microtubule binding
C	0016020	cellular_component	membrane
C	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
C	0016787	molecular_function	hydrolase activity
C	0019003	molecular_function	GDP binding
C	0019901	molecular_function	protein kinase binding
C	0030139	cellular_component	endocytic vesicle
C	0031410	cellular_component	cytoplasmic vesicle
C	0042583	cellular_component	chromaffin granule
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0045202	cellular_component	synapse
C	0051260	biological_process	protein homooligomerization
C	0051289	biological_process	protein homotetramerization
C	0070062	cellular_component	extracellular exosome
C	0097494	biological_process	regulation of vesicle size
C	0098793	cellular_component	presynapse
C	0099049	biological_process	clathrin coat assembly involved in endocytosis
C	0099050	biological_process	vesicle scission
C2	0000166	molecular_function	nucleotide binding
C2	0003723	molecular_function	RNA binding
C2	0003924	molecular_function	GTPase activity
C2	0005515	molecular_function	protein binding
C2	0005525	molecular_function	GTP binding
C2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
C2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
C2	0005737	cellular_component	cytoplasm
C2	0005874	cellular_component	microtubule
C2	0005886	cellular_component	plasma membrane
C2	0005905	cellular_component	clathrin-coated pit
C2	0006897	biological_process	endocytosis
C2	0006898	biological_process	receptor-mediated endocytosis
C2	0007032	biological_process	endosome organization
C2	0008017	molecular_function	microtubule binding
C2	0016020	cellular_component	membrane
C2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
C2	0016787	molecular_function	hydrolase activity
C2	0019003	molecular_function	GDP binding
C2	0019901	molecular_function	protein kinase binding
C2	0030139	cellular_component	endocytic vesicle
C2	0031410	cellular_component	cytoplasmic vesicle
C2	0042583	cellular_component	chromaffin granule
C2	0042802	molecular_function	identical protein binding
C2	0042803	molecular_function	protein homodimerization activity
C2	0045202	cellular_component	synapse
C2	0051260	biological_process	protein homooligomerization
C2	0051289	biological_process	protein homotetramerization
C2	0070062	cellular_component	extracellular exosome
C2	0097494	biological_process	regulation of vesicle size
C2	0098793	cellular_component	presynapse
C2	0099049	biological_process	clathrin coat assembly involved in endocytosis
C2	0099050	biological_process	vesicle scission
D	0000166	molecular_function	nucleotide binding
D	0003723	molecular_function	RNA binding
D	0003924	molecular_function	GTPase activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
D	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
D	0005737	cellular_component	cytoplasm
D	0005874	cellular_component	microtubule
D	0005886	cellular_component	plasma membrane
D	0005905	cellular_component	clathrin-coated pit
D	0006897	biological_process	endocytosis
D	0006898	biological_process	receptor-mediated endocytosis
D	0007032	biological_process	endosome organization
D	0008017	molecular_function	microtubule binding
D	0016020	cellular_component	membrane
D	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
D	0016787	molecular_function	hydrolase activity
D	0019003	molecular_function	GDP binding
D	0019901	molecular_function	protein kinase binding
D	0030139	cellular_component	endocytic vesicle
D	0031410	cellular_component	cytoplasmic vesicle
D	0042583	cellular_component	chromaffin granule
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0045202	cellular_component	synapse
D	0051260	biological_process	protein homooligomerization
D	0051289	biological_process	protein homotetramerization
D	0070062	cellular_component	extracellular exosome
D	0097494	biological_process	regulation of vesicle size
D	0098793	cellular_component	presynapse
D	0099049	biological_process	clathrin coat assembly involved in endocytosis
D	0099050	biological_process	vesicle scission
D2	0000166	molecular_function	nucleotide binding
D2	0003723	molecular_function	RNA binding
D2	0003924	molecular_function	GTPase activity
D2	0005515	molecular_function	protein binding
D2	0005525	molecular_function	GTP binding
D2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
D2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
D2	0005737	cellular_component	cytoplasm
D2	0005874	cellular_component	microtubule
D2	0005886	cellular_component	plasma membrane
D2	0005905	cellular_component	clathrin-coated pit
D2	0006897	biological_process	endocytosis
D2	0006898	biological_process	receptor-mediated endocytosis
D2	0007032	biological_process	endosome organization
D2	0008017	molecular_function	microtubule binding
D2	0016020	cellular_component	membrane
D2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
D2	0016787	molecular_function	hydrolase activity
D2	0019003	molecular_function	GDP binding
D2	0019901	molecular_function	protein kinase binding
D2	0030139	cellular_component	endocytic vesicle
D2	0031410	cellular_component	cytoplasmic vesicle
D2	0042583	cellular_component	chromaffin granule
D2	0042802	molecular_function	identical protein binding
D2	0042803	molecular_function	protein homodimerization activity
D2	0045202	cellular_component	synapse
D2	0051260	biological_process	protein homooligomerization
D2	0051289	biological_process	protein homotetramerization
D2	0070062	cellular_component	extracellular exosome
D2	0097494	biological_process	regulation of vesicle size
D2	0098793	cellular_component	presynapse
D2	0099049	biological_process	clathrin coat assembly involved in endocytosis
D2	0099050	biological_process	vesicle scission
E	0000166	molecular_function	nucleotide binding
E	0003723	molecular_function	RNA binding
E	0003924	molecular_function	GTPase activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
E	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
E	0005737	cellular_component	cytoplasm
E	0005874	cellular_component	microtubule
E	0005886	cellular_component	plasma membrane
E	0005905	cellular_component	clathrin-coated pit
E	0006897	biological_process	endocytosis
E	0006898	biological_process	receptor-mediated endocytosis
E	0007032	biological_process	endosome organization
E	0008017	molecular_function	microtubule binding
E	0016020	cellular_component	membrane
E	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
E	0016787	molecular_function	hydrolase activity
E	0019003	molecular_function	GDP binding
E	0019901	molecular_function	protein kinase binding
E	0030139	cellular_component	endocytic vesicle
E	0031410	cellular_component	cytoplasmic vesicle
E	0042583	cellular_component	chromaffin granule
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0045202	cellular_component	synapse
E	0051260	biological_process	protein homooligomerization
E	0051289	biological_process	protein homotetramerization
E	0070062	cellular_component	extracellular exosome
E	0097494	biological_process	regulation of vesicle size
E	0098793	cellular_component	presynapse
E	0099049	biological_process	clathrin coat assembly involved in endocytosis
E	0099050	biological_process	vesicle scission
E2	0000166	molecular_function	nucleotide binding
E2	0003723	molecular_function	RNA binding
E2	0003924	molecular_function	GTPase activity
E2	0005515	molecular_function	protein binding
E2	0005525	molecular_function	GTP binding
E2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
E2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
E2	0005737	cellular_component	cytoplasm
E2	0005874	cellular_component	microtubule
E2	0005886	cellular_component	plasma membrane
E2	0005905	cellular_component	clathrin-coated pit
E2	0006897	biological_process	endocytosis
E2	0006898	biological_process	receptor-mediated endocytosis
E2	0007032	biological_process	endosome organization
E2	0008017	molecular_function	microtubule binding
E2	0016020	cellular_component	membrane
E2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
E2	0016787	molecular_function	hydrolase activity
E2	0019003	molecular_function	GDP binding
E2	0019901	molecular_function	protein kinase binding
E2	0030139	cellular_component	endocytic vesicle
E2	0031410	cellular_component	cytoplasmic vesicle
E2	0042583	cellular_component	chromaffin granule
E2	0042802	molecular_function	identical protein binding
E2	0042803	molecular_function	protein homodimerization activity
E2	0045202	cellular_component	synapse
E2	0051260	biological_process	protein homooligomerization
E2	0051289	biological_process	protein homotetramerization
E2	0070062	cellular_component	extracellular exosome
E2	0097494	biological_process	regulation of vesicle size
E2	0098793	cellular_component	presynapse
E2	0099049	biological_process	clathrin coat assembly involved in endocytosis
E2	0099050	biological_process	vesicle scission
F	0000166	molecular_function	nucleotide binding
F	0003723	molecular_function	RNA binding
F	0003924	molecular_function	GTPase activity
F	0005515	molecular_function	protein binding
F	0005525	molecular_function	GTP binding
F	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
F	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
F	0005737	cellular_component	cytoplasm
F	0005874	cellular_component	microtubule
F	0005886	cellular_component	plasma membrane
F	0005905	cellular_component	clathrin-coated pit
F	0006897	biological_process	endocytosis
F	0006898	biological_process	receptor-mediated endocytosis
F	0007032	biological_process	endosome organization
F	0008017	molecular_function	microtubule binding
F	0016020	cellular_component	membrane
F	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
F	0016787	molecular_function	hydrolase activity
F	0019003	molecular_function	GDP binding
F	0019901	molecular_function	protein kinase binding
F	0030139	cellular_component	endocytic vesicle
F	0031410	cellular_component	cytoplasmic vesicle
F	0042583	cellular_component	chromaffin granule
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0045202	cellular_component	synapse
F	0051260	biological_process	protein homooligomerization
F	0051289	biological_process	protein homotetramerization
F	0070062	cellular_component	extracellular exosome
F	0097494	biological_process	regulation of vesicle size
F	0098793	cellular_component	presynapse
F	0099049	biological_process	clathrin coat assembly involved in endocytosis
F	0099050	biological_process	vesicle scission
F2	0000166	molecular_function	nucleotide binding
F2	0003723	molecular_function	RNA binding
F2	0003924	molecular_function	GTPase activity
F2	0005515	molecular_function	protein binding
F2	0005525	molecular_function	GTP binding
F2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
F2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
F2	0005737	cellular_component	cytoplasm
F2	0005874	cellular_component	microtubule
F2	0005886	cellular_component	plasma membrane
F2	0005905	cellular_component	clathrin-coated pit
F2	0006897	biological_process	endocytosis
F2	0006898	biological_process	receptor-mediated endocytosis
F2	0007032	biological_process	endosome organization
F2	0008017	molecular_function	microtubule binding
F2	0016020	cellular_component	membrane
F2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
F2	0016787	molecular_function	hydrolase activity
F2	0019003	molecular_function	GDP binding
F2	0019901	molecular_function	protein kinase binding
F2	0030139	cellular_component	endocytic vesicle
F2	0031410	cellular_component	cytoplasmic vesicle
F2	0042583	cellular_component	chromaffin granule
F2	0042802	molecular_function	identical protein binding
F2	0042803	molecular_function	protein homodimerization activity
F2	0045202	cellular_component	synapse
F2	0051260	biological_process	protein homooligomerization
F2	0051289	biological_process	protein homotetramerization
F2	0070062	cellular_component	extracellular exosome
F2	0097494	biological_process	regulation of vesicle size
F2	0098793	cellular_component	presynapse
F2	0099049	biological_process	clathrin coat assembly involved in endocytosis
F2	0099050	biological_process	vesicle scission
G	0000166	molecular_function	nucleotide binding
G	0003723	molecular_function	RNA binding
G	0003924	molecular_function	GTPase activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
G	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
G	0005737	cellular_component	cytoplasm
G	0005874	cellular_component	microtubule
G	0005886	cellular_component	plasma membrane
G	0005905	cellular_component	clathrin-coated pit
G	0006897	biological_process	endocytosis
G	0006898	biological_process	receptor-mediated endocytosis
G	0007032	biological_process	endosome organization
G	0008017	molecular_function	microtubule binding
G	0016020	cellular_component	membrane
G	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
G	0016787	molecular_function	hydrolase activity
G	0019003	molecular_function	GDP binding
G	0019901	molecular_function	protein kinase binding
G	0030139	cellular_component	endocytic vesicle
G	0031410	cellular_component	cytoplasmic vesicle
G	0042583	cellular_component	chromaffin granule
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0045202	cellular_component	synapse
G	0051260	biological_process	protein homooligomerization
G	0051289	biological_process	protein homotetramerization
G	0070062	cellular_component	extracellular exosome
G	0097494	biological_process	regulation of vesicle size
G	0098793	cellular_component	presynapse
G	0099049	biological_process	clathrin coat assembly involved in endocytosis
G	0099050	biological_process	vesicle scission
G2	0000166	molecular_function	nucleotide binding
G2	0003723	molecular_function	RNA binding
G2	0003924	molecular_function	GTPase activity
G2	0005515	molecular_function	protein binding
G2	0005525	molecular_function	GTP binding
G2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
G2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
G2	0005737	cellular_component	cytoplasm
G2	0005874	cellular_component	microtubule
G2	0005886	cellular_component	plasma membrane
G2	0005905	cellular_component	clathrin-coated pit
G2	0006897	biological_process	endocytosis
G2	0006898	biological_process	receptor-mediated endocytosis
G2	0007032	biological_process	endosome organization
G2	0008017	molecular_function	microtubule binding
G2	0016020	cellular_component	membrane
G2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
G2	0016787	molecular_function	hydrolase activity
G2	0019003	molecular_function	GDP binding
G2	0019901	molecular_function	protein kinase binding
G2	0030139	cellular_component	endocytic vesicle
G2	0031410	cellular_component	cytoplasmic vesicle
G2	0042583	cellular_component	chromaffin granule
G2	0042802	molecular_function	identical protein binding
G2	0042803	molecular_function	protein homodimerization activity
G2	0045202	cellular_component	synapse
G2	0051260	biological_process	protein homooligomerization
G2	0051289	biological_process	protein homotetramerization
G2	0070062	cellular_component	extracellular exosome
G2	0097494	biological_process	regulation of vesicle size
G2	0098793	cellular_component	presynapse
G2	0099049	biological_process	clathrin coat assembly involved in endocytosis
G2	0099050	biological_process	vesicle scission
H	0000166	molecular_function	nucleotide binding
H	0003723	molecular_function	RNA binding
H	0003924	molecular_function	GTPase activity
H	0005515	molecular_function	protein binding
H	0005525	molecular_function	GTP binding
H	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
H	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
H	0005737	cellular_component	cytoplasm
H	0005874	cellular_component	microtubule
H	0005886	cellular_component	plasma membrane
H	0005905	cellular_component	clathrin-coated pit
H	0006897	biological_process	endocytosis
H	0006898	biological_process	receptor-mediated endocytosis
H	0007032	biological_process	endosome organization
H	0008017	molecular_function	microtubule binding
H	0016020	cellular_component	membrane
H	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
H	0016787	molecular_function	hydrolase activity
H	0019003	molecular_function	GDP binding
H	0019901	molecular_function	protein kinase binding
H	0030139	cellular_component	endocytic vesicle
H	0031410	cellular_component	cytoplasmic vesicle
H	0042583	cellular_component	chromaffin granule
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0045202	cellular_component	synapse
H	0051260	biological_process	protein homooligomerization
H	0051289	biological_process	protein homotetramerization
H	0070062	cellular_component	extracellular exosome
H	0097494	biological_process	regulation of vesicle size
H	0098793	cellular_component	presynapse
H	0099049	biological_process	clathrin coat assembly involved in endocytosis
H	0099050	biological_process	vesicle scission
H2	0000166	molecular_function	nucleotide binding
H2	0003723	molecular_function	RNA binding
H2	0003924	molecular_function	GTPase activity
H2	0005515	molecular_function	protein binding
H2	0005525	molecular_function	GTP binding
H2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
H2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
H2	0005737	cellular_component	cytoplasm
H2	0005874	cellular_component	microtubule
H2	0005886	cellular_component	plasma membrane
H2	0005905	cellular_component	clathrin-coated pit
H2	0006897	biological_process	endocytosis
H2	0006898	biological_process	receptor-mediated endocytosis
H2	0007032	biological_process	endosome organization
H2	0008017	molecular_function	microtubule binding
H2	0016020	cellular_component	membrane
H2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
H2	0016787	molecular_function	hydrolase activity
H2	0019003	molecular_function	GDP binding
H2	0019901	molecular_function	protein kinase binding
H2	0030139	cellular_component	endocytic vesicle
H2	0031410	cellular_component	cytoplasmic vesicle
H2	0042583	cellular_component	chromaffin granule
H2	0042802	molecular_function	identical protein binding
H2	0042803	molecular_function	protein homodimerization activity
H2	0045202	cellular_component	synapse
H2	0051260	biological_process	protein homooligomerization
H2	0051289	biological_process	protein homotetramerization
H2	0070062	cellular_component	extracellular exosome
H2	0097494	biological_process	regulation of vesicle size
H2	0098793	cellular_component	presynapse
H2	0099049	biological_process	clathrin coat assembly involved in endocytosis
H2	0099050	biological_process	vesicle scission
I	0000166	molecular_function	nucleotide binding
I	0003723	molecular_function	RNA binding
I	0003924	molecular_function	GTPase activity
I	0005515	molecular_function	protein binding
I	0005525	molecular_function	GTP binding
I	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
I	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
I	0005737	cellular_component	cytoplasm
I	0005874	cellular_component	microtubule
I	0005886	cellular_component	plasma membrane
I	0005905	cellular_component	clathrin-coated pit
I	0006897	biological_process	endocytosis
I	0006898	biological_process	receptor-mediated endocytosis
I	0007032	biological_process	endosome organization
I	0008017	molecular_function	microtubule binding
I	0016020	cellular_component	membrane
I	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
I	0016787	molecular_function	hydrolase activity
I	0019003	molecular_function	GDP binding
I	0019901	molecular_function	protein kinase binding
I	0030139	cellular_component	endocytic vesicle
I	0031410	cellular_component	cytoplasmic vesicle
I	0042583	cellular_component	chromaffin granule
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0045202	cellular_component	synapse
I	0051260	biological_process	protein homooligomerization
I	0051289	biological_process	protein homotetramerization
I	0070062	cellular_component	extracellular exosome
I	0097494	biological_process	regulation of vesicle size
I	0098793	cellular_component	presynapse
I	0099049	biological_process	clathrin coat assembly involved in endocytosis
I	0099050	biological_process	vesicle scission
I2	0000166	molecular_function	nucleotide binding
I2	0003723	molecular_function	RNA binding
I2	0003924	molecular_function	GTPase activity
I2	0005515	molecular_function	protein binding
I2	0005525	molecular_function	GTP binding
I2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
I2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
I2	0005737	cellular_component	cytoplasm
I2	0005874	cellular_component	microtubule
I2	0005886	cellular_component	plasma membrane
I2	0005905	cellular_component	clathrin-coated pit
I2	0006897	biological_process	endocytosis
I2	0006898	biological_process	receptor-mediated endocytosis
I2	0007032	biological_process	endosome organization
I2	0008017	molecular_function	microtubule binding
I2	0016020	cellular_component	membrane
I2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
I2	0016787	molecular_function	hydrolase activity
I2	0019003	molecular_function	GDP binding
I2	0019901	molecular_function	protein kinase binding
I2	0030139	cellular_component	endocytic vesicle
I2	0031410	cellular_component	cytoplasmic vesicle
I2	0042583	cellular_component	chromaffin granule
I2	0042802	molecular_function	identical protein binding
I2	0042803	molecular_function	protein homodimerization activity
I2	0045202	cellular_component	synapse
I2	0051260	biological_process	protein homooligomerization
I2	0051289	biological_process	protein homotetramerization
I2	0070062	cellular_component	extracellular exosome
I2	0097494	biological_process	regulation of vesicle size
I2	0098793	cellular_component	presynapse
I2	0099049	biological_process	clathrin coat assembly involved in endocytosis
I2	0099050	biological_process	vesicle scission
J	0000166	molecular_function	nucleotide binding
J	0003723	molecular_function	RNA binding
J	0003924	molecular_function	GTPase activity
J	0005515	molecular_function	protein binding
J	0005525	molecular_function	GTP binding
J	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
J	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
J	0005737	cellular_component	cytoplasm
J	0005874	cellular_component	microtubule
J	0005886	cellular_component	plasma membrane
J	0005905	cellular_component	clathrin-coated pit
J	0006897	biological_process	endocytosis
J	0006898	biological_process	receptor-mediated endocytosis
J	0007032	biological_process	endosome organization
J	0008017	molecular_function	microtubule binding
J	0016020	cellular_component	membrane
J	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
J	0016787	molecular_function	hydrolase activity
J	0019003	molecular_function	GDP binding
J	0019901	molecular_function	protein kinase binding
J	0030139	cellular_component	endocytic vesicle
J	0031410	cellular_component	cytoplasmic vesicle
J	0042583	cellular_component	chromaffin granule
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0045202	cellular_component	synapse
J	0051260	biological_process	protein homooligomerization
J	0051289	biological_process	protein homotetramerization
J	0070062	cellular_component	extracellular exosome
J	0097494	biological_process	regulation of vesicle size
J	0098793	cellular_component	presynapse
J	0099049	biological_process	clathrin coat assembly involved in endocytosis
J	0099050	biological_process	vesicle scission
J2	0000166	molecular_function	nucleotide binding
J2	0003723	molecular_function	RNA binding
J2	0003924	molecular_function	GTPase activity
J2	0005515	molecular_function	protein binding
J2	0005525	molecular_function	GTP binding
J2	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
J2	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
J2	0005737	cellular_component	cytoplasm
J2	0005874	cellular_component	microtubule
J2	0005886	cellular_component	plasma membrane
J2	0005905	cellular_component	clathrin-coated pit
J2	0006897	biological_process	endocytosis
J2	0006898	biological_process	receptor-mediated endocytosis
J2	0007032	biological_process	endosome organization
J2	0008017	molecular_function	microtubule binding
J2	0016020	cellular_component	membrane
J2	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
J2	0016787	molecular_function	hydrolase activity
J2	0019003	molecular_function	GDP binding
J2	0019901	molecular_function	protein kinase binding
J2	0030139	cellular_component	endocytic vesicle
J2	0031410	cellular_component	cytoplasmic vesicle
J2	0042583	cellular_component	chromaffin granule
J2	0042802	molecular_function	identical protein binding
J2	0042803	molecular_function	protein homodimerization activity
J2	0045202	cellular_component	synapse
J2	0051260	biological_process	protein homooligomerization
J2	0051289	biological_process	protein homotetramerization
J2	0070062	cellular_component	extracellular exosome
J2	0097494	biological_process	regulation of vesicle size
J2	0098793	cellular_component	presynapse
J2	0099049	biological_process	clathrin coat assembly involved in endocytosis
J2	0099050	biological_process	vesicle scission
K	0000166	molecular_function	nucleotide binding
K	0003723	molecular_function	RNA binding
K	0003924	molecular_function	GTPase activity
K	0005515	molecular_function	protein binding
K	0005525	molecular_function	GTP binding
K	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
K	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
K	0005737	cellular_component	cytoplasm
K	0005874	cellular_component	microtubule
K	0005886	cellular_component	plasma membrane
K	0005905	cellular_component	clathrin-coated pit
K	0006897	biological_process	endocytosis
K	0006898	biological_process	receptor-mediated endocytosis
K	0007032	biological_process	endosome organization
K	0008017	molecular_function	microtubule binding
K	0016020	cellular_component	membrane
K	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
K	0016787	molecular_function	hydrolase activity
K	0019003	molecular_function	GDP binding
K	0019901	molecular_function	protein kinase binding
K	0030139	cellular_component	endocytic vesicle
K	0031410	cellular_component	cytoplasmic vesicle
K	0042583	cellular_component	chromaffin granule
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0045202	cellular_component	synapse
K	0051260	biological_process	protein homooligomerization
K	0051289	biological_process	protein homotetramerization
K	0070062	cellular_component	extracellular exosome
K	0097494	biological_process	regulation of vesicle size
K	0098793	cellular_component	presynapse
K	0099049	biological_process	clathrin coat assembly involved in endocytosis
K	0099050	biological_process	vesicle scission
L	0000166	molecular_function	nucleotide binding
L	0003723	molecular_function	RNA binding
L	0003924	molecular_function	GTPase activity
L	0005515	molecular_function	protein binding
L	0005525	molecular_function	GTP binding
L	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
L	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
L	0005737	cellular_component	cytoplasm
L	0005874	cellular_component	microtubule
L	0005886	cellular_component	plasma membrane
L	0005905	cellular_component	clathrin-coated pit
L	0006897	biological_process	endocytosis
L	0006898	biological_process	receptor-mediated endocytosis
L	0007032	biological_process	endosome organization
L	0008017	molecular_function	microtubule binding
L	0016020	cellular_component	membrane
L	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
L	0016787	molecular_function	hydrolase activity
L	0019003	molecular_function	GDP binding
L	0019901	molecular_function	protein kinase binding
L	0030139	cellular_component	endocytic vesicle
L	0031410	cellular_component	cytoplasmic vesicle
L	0042583	cellular_component	chromaffin granule
L	0042802	molecular_function	identical protein binding
L	0042803	molecular_function	protein homodimerization activity
L	0045202	cellular_component	synapse
L	0051260	biological_process	protein homooligomerization
L	0051289	biological_process	protein homotetramerization
L	0070062	cellular_component	extracellular exosome
L	0097494	biological_process	regulation of vesicle size
L	0098793	cellular_component	presynapse
L	0099049	biological_process	clathrin coat assembly involved in endocytosis
L	0099050	biological_process	vesicle scission
M	0000166	molecular_function	nucleotide binding
M	0003723	molecular_function	RNA binding
M	0003924	molecular_function	GTPase activity
M	0005515	molecular_function	protein binding
M	0005525	molecular_function	GTP binding
M	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
M	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
M	0005737	cellular_component	cytoplasm
M	0005874	cellular_component	microtubule
M	0005886	cellular_component	plasma membrane
M	0005905	cellular_component	clathrin-coated pit
M	0006897	biological_process	endocytosis
M	0006898	biological_process	receptor-mediated endocytosis
M	0007032	biological_process	endosome organization
M	0008017	molecular_function	microtubule binding
M	0016020	cellular_component	membrane
M	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
M	0016787	molecular_function	hydrolase activity
M	0019003	molecular_function	GDP binding
M	0019901	molecular_function	protein kinase binding
M	0030139	cellular_component	endocytic vesicle
M	0031410	cellular_component	cytoplasmic vesicle
M	0042583	cellular_component	chromaffin granule
M	0042802	molecular_function	identical protein binding
M	0042803	molecular_function	protein homodimerization activity
M	0045202	cellular_component	synapse
M	0051260	biological_process	protein homooligomerization
M	0051289	biological_process	protein homotetramerization
M	0070062	cellular_component	extracellular exosome
M	0097494	biological_process	regulation of vesicle size
M	0098793	cellular_component	presynapse
M	0099049	biological_process	clathrin coat assembly involved in endocytosis
M	0099050	biological_process	vesicle scission
N	0000166	molecular_function	nucleotide binding
N	0003723	molecular_function	RNA binding
N	0003924	molecular_function	GTPase activity
N	0005515	molecular_function	protein binding
N	0005525	molecular_function	GTP binding
N	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
N	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
N	0005737	cellular_component	cytoplasm
N	0005874	cellular_component	microtubule
N	0005886	cellular_component	plasma membrane
N	0005905	cellular_component	clathrin-coated pit
N	0006897	biological_process	endocytosis
N	0006898	biological_process	receptor-mediated endocytosis
N	0007032	biological_process	endosome organization
N	0008017	molecular_function	microtubule binding
N	0016020	cellular_component	membrane
N	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
N	0016787	molecular_function	hydrolase activity
N	0019003	molecular_function	GDP binding
N	0019901	molecular_function	protein kinase binding
N	0030139	cellular_component	endocytic vesicle
N	0031410	cellular_component	cytoplasmic vesicle
N	0042583	cellular_component	chromaffin granule
N	0042802	molecular_function	identical protein binding
N	0042803	molecular_function	protein homodimerization activity
N	0045202	cellular_component	synapse
N	0051260	biological_process	protein homooligomerization
N	0051289	biological_process	protein homotetramerization
N	0070062	cellular_component	extracellular exosome
N	0097494	biological_process	regulation of vesicle size
N	0098793	cellular_component	presynapse
N	0099049	biological_process	clathrin coat assembly involved in endocytosis
N	0099050	biological_process	vesicle scission
O	0000166	molecular_function	nucleotide binding
O	0003723	molecular_function	RNA binding
O	0003924	molecular_function	GTPase activity
O	0005515	molecular_function	protein binding
O	0005525	molecular_function	GTP binding
O	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
O	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
O	0005737	cellular_component	cytoplasm
O	0005874	cellular_component	microtubule
O	0005886	cellular_component	plasma membrane
O	0005905	cellular_component	clathrin-coated pit
O	0006897	biological_process	endocytosis
O	0006898	biological_process	receptor-mediated endocytosis
O	0007032	biological_process	endosome organization
O	0008017	molecular_function	microtubule binding
O	0016020	cellular_component	membrane
O	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
O	0016787	molecular_function	hydrolase activity
O	0019003	molecular_function	GDP binding
O	0019901	molecular_function	protein kinase binding
O	0030139	cellular_component	endocytic vesicle
O	0031410	cellular_component	cytoplasmic vesicle
O	0042583	cellular_component	chromaffin granule
O	0042802	molecular_function	identical protein binding
O	0042803	molecular_function	protein homodimerization activity
O	0045202	cellular_component	synapse
O	0051260	biological_process	protein homooligomerization
O	0051289	biological_process	protein homotetramerization
O	0070062	cellular_component	extracellular exosome
O	0097494	biological_process	regulation of vesicle size
O	0098793	cellular_component	presynapse
O	0099049	biological_process	clathrin coat assembly involved in endocytosis
O	0099050	biological_process	vesicle scission
P	0000166	molecular_function	nucleotide binding
P	0003723	molecular_function	RNA binding
P	0003924	molecular_function	GTPase activity
P	0005515	molecular_function	protein binding
P	0005525	molecular_function	GTP binding
P	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
P	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
P	0005737	cellular_component	cytoplasm
P	0005874	cellular_component	microtubule
P	0005886	cellular_component	plasma membrane
P	0005905	cellular_component	clathrin-coated pit
P	0006897	biological_process	endocytosis
P	0006898	biological_process	receptor-mediated endocytosis
P	0007032	biological_process	endosome organization
P	0008017	molecular_function	microtubule binding
P	0016020	cellular_component	membrane
P	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
P	0016787	molecular_function	hydrolase activity
P	0019003	molecular_function	GDP binding
P	0019901	molecular_function	protein kinase binding
P	0030139	cellular_component	endocytic vesicle
P	0031410	cellular_component	cytoplasmic vesicle
P	0042583	cellular_component	chromaffin granule
P	0042802	molecular_function	identical protein binding
P	0042803	molecular_function	protein homodimerization activity
P	0045202	cellular_component	synapse
P	0051260	biological_process	protein homooligomerization
P	0051289	biological_process	protein homotetramerization
P	0070062	cellular_component	extracellular exosome
P	0097494	biological_process	regulation of vesicle size
P	0098793	cellular_component	presynapse
P	0099049	biological_process	clathrin coat assembly involved in endocytosis
P	0099050	biological_process	vesicle scission
Q	0000166	molecular_function	nucleotide binding
Q	0003723	molecular_function	RNA binding
Q	0003924	molecular_function	GTPase activity
Q	0005515	molecular_function	protein binding
Q	0005525	molecular_function	GTP binding
Q	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
Q	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
Q	0005737	cellular_component	cytoplasm
Q	0005874	cellular_component	microtubule
Q	0005886	cellular_component	plasma membrane
Q	0005905	cellular_component	clathrin-coated pit
Q	0006897	biological_process	endocytosis
Q	0006898	biological_process	receptor-mediated endocytosis
Q	0007032	biological_process	endosome organization
Q	0008017	molecular_function	microtubule binding
Q	0016020	cellular_component	membrane
Q	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
Q	0016787	molecular_function	hydrolase activity
Q	0019003	molecular_function	GDP binding
Q	0019901	molecular_function	protein kinase binding
Q	0030139	cellular_component	endocytic vesicle
Q	0031410	cellular_component	cytoplasmic vesicle
Q	0042583	cellular_component	chromaffin granule
Q	0042802	molecular_function	identical protein binding
Q	0042803	molecular_function	protein homodimerization activity
Q	0045202	cellular_component	synapse
Q	0051260	biological_process	protein homooligomerization
Q	0051289	biological_process	protein homotetramerization
Q	0070062	cellular_component	extracellular exosome
Q	0097494	biological_process	regulation of vesicle size
Q	0098793	cellular_component	presynapse
Q	0099049	biological_process	clathrin coat assembly involved in endocytosis
Q	0099050	biological_process	vesicle scission
R	0000166	molecular_function	nucleotide binding
R	0003723	molecular_function	RNA binding
R	0003924	molecular_function	GTPase activity
R	0005515	molecular_function	protein binding
R	0005525	molecular_function	GTP binding
R	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
R	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
R	0005737	cellular_component	cytoplasm
R	0005874	cellular_component	microtubule
R	0005886	cellular_component	plasma membrane
R	0005905	cellular_component	clathrin-coated pit
R	0006897	biological_process	endocytosis
R	0006898	biological_process	receptor-mediated endocytosis
R	0007032	biological_process	endosome organization
R	0008017	molecular_function	microtubule binding
R	0016020	cellular_component	membrane
R	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
R	0016787	molecular_function	hydrolase activity
R	0019003	molecular_function	GDP binding
R	0019901	molecular_function	protein kinase binding
R	0030139	cellular_component	endocytic vesicle
R	0031410	cellular_component	cytoplasmic vesicle
R	0042583	cellular_component	chromaffin granule
R	0042802	molecular_function	identical protein binding
R	0042803	molecular_function	protein homodimerization activity
R	0045202	cellular_component	synapse
R	0051260	biological_process	protein homooligomerization
R	0051289	biological_process	protein homotetramerization
R	0070062	cellular_component	extracellular exosome
R	0097494	biological_process	regulation of vesicle size
R	0098793	cellular_component	presynapse
R	0099049	biological_process	clathrin coat assembly involved in endocytosis
R	0099050	biological_process	vesicle scission
S	0000166	molecular_function	nucleotide binding
S	0003723	molecular_function	RNA binding
S	0003924	molecular_function	GTPase activity
S	0005515	molecular_function	protein binding
S	0005525	molecular_function	GTP binding
S	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
S	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
S	0005737	cellular_component	cytoplasm
S	0005874	cellular_component	microtubule
S	0005886	cellular_component	plasma membrane
S	0005905	cellular_component	clathrin-coated pit
S	0006897	biological_process	endocytosis
S	0006898	biological_process	receptor-mediated endocytosis
S	0007032	biological_process	endosome organization
S	0008017	molecular_function	microtubule binding
S	0016020	cellular_component	membrane
S	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
S	0016787	molecular_function	hydrolase activity
S	0019003	molecular_function	GDP binding
S	0019901	molecular_function	protein kinase binding
S	0030139	cellular_component	endocytic vesicle
S	0031410	cellular_component	cytoplasmic vesicle
S	0042583	cellular_component	chromaffin granule
S	0042802	molecular_function	identical protein binding
S	0042803	molecular_function	protein homodimerization activity
S	0045202	cellular_component	synapse
S	0051260	biological_process	protein homooligomerization
S	0051289	biological_process	protein homotetramerization
S	0070062	cellular_component	extracellular exosome
S	0097494	biological_process	regulation of vesicle size
S	0098793	cellular_component	presynapse
S	0099049	biological_process	clathrin coat assembly involved in endocytosis
S	0099050	biological_process	vesicle scission
T	0000166	molecular_function	nucleotide binding
T	0003723	molecular_function	RNA binding
T	0003924	molecular_function	GTPase activity
T	0005515	molecular_function	protein binding
T	0005525	molecular_function	GTP binding
T	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
T	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
T	0005737	cellular_component	cytoplasm
T	0005874	cellular_component	microtubule
T	0005886	cellular_component	plasma membrane
T	0005905	cellular_component	clathrin-coated pit
T	0006897	biological_process	endocytosis
T	0006898	biological_process	receptor-mediated endocytosis
T	0007032	biological_process	endosome organization
T	0008017	molecular_function	microtubule binding
T	0016020	cellular_component	membrane
T	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
T	0016787	molecular_function	hydrolase activity
T	0019003	molecular_function	GDP binding
T	0019901	molecular_function	protein kinase binding
T	0030139	cellular_component	endocytic vesicle
T	0031410	cellular_component	cytoplasmic vesicle
T	0042583	cellular_component	chromaffin granule
T	0042802	molecular_function	identical protein binding
T	0042803	molecular_function	protein homodimerization activity
T	0045202	cellular_component	synapse
T	0051260	biological_process	protein homooligomerization
T	0051289	biological_process	protein homotetramerization
T	0070062	cellular_component	extracellular exosome
T	0097494	biological_process	regulation of vesicle size
T	0098793	cellular_component	presynapse
T	0099049	biological_process	clathrin coat assembly involved in endocytosis
T	0099050	biological_process	vesicle scission
U	0000166	molecular_function	nucleotide binding
U	0003723	molecular_function	RNA binding
U	0003924	molecular_function	GTPase activity
U	0005515	molecular_function	protein binding
U	0005525	molecular_function	GTP binding
U	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
U	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
U	0005737	cellular_component	cytoplasm
U	0005874	cellular_component	microtubule
U	0005886	cellular_component	plasma membrane
U	0005905	cellular_component	clathrin-coated pit
U	0006897	biological_process	endocytosis
U	0006898	biological_process	receptor-mediated endocytosis
U	0007032	biological_process	endosome organization
U	0008017	molecular_function	microtubule binding
U	0016020	cellular_component	membrane
U	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
U	0016787	molecular_function	hydrolase activity
U	0019003	molecular_function	GDP binding
U	0019901	molecular_function	protein kinase binding
U	0030139	cellular_component	endocytic vesicle
U	0031410	cellular_component	cytoplasmic vesicle
U	0042583	cellular_component	chromaffin granule
U	0042802	molecular_function	identical protein binding
U	0042803	molecular_function	protein homodimerization activity
U	0045202	cellular_component	synapse
U	0051260	biological_process	protein homooligomerization
U	0051289	biological_process	protein homotetramerization
U	0070062	cellular_component	extracellular exosome
U	0097494	biological_process	regulation of vesicle size
U	0098793	cellular_component	presynapse
U	0099049	biological_process	clathrin coat assembly involved in endocytosis
U	0099050	biological_process	vesicle scission
V	0000166	molecular_function	nucleotide binding
V	0003723	molecular_function	RNA binding
V	0003924	molecular_function	GTPase activity
V	0005515	molecular_function	protein binding
V	0005525	molecular_function	GTP binding
V	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
V	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
V	0005737	cellular_component	cytoplasm
V	0005874	cellular_component	microtubule
V	0005886	cellular_component	plasma membrane
V	0005905	cellular_component	clathrin-coated pit
V	0006897	biological_process	endocytosis
V	0006898	biological_process	receptor-mediated endocytosis
V	0007032	biological_process	endosome organization
V	0008017	molecular_function	microtubule binding
V	0016020	cellular_component	membrane
V	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
V	0016787	molecular_function	hydrolase activity
V	0019003	molecular_function	GDP binding
V	0019901	molecular_function	protein kinase binding
V	0030139	cellular_component	endocytic vesicle
V	0031410	cellular_component	cytoplasmic vesicle
V	0042583	cellular_component	chromaffin granule
V	0042802	molecular_function	identical protein binding
V	0042803	molecular_function	protein homodimerization activity
V	0045202	cellular_component	synapse
V	0051260	biological_process	protein homooligomerization
V	0051289	biological_process	protein homotetramerization
V	0070062	cellular_component	extracellular exosome
V	0097494	biological_process	regulation of vesicle size
V	0098793	cellular_component	presynapse
V	0099049	biological_process	clathrin coat assembly involved in endocytosis
V	0099050	biological_process	vesicle scission
W	0000166	molecular_function	nucleotide binding
W	0003723	molecular_function	RNA binding
W	0003924	molecular_function	GTPase activity
W	0005515	molecular_function	protein binding
W	0005525	molecular_function	GTP binding
W	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
W	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
W	0005737	cellular_component	cytoplasm
W	0005874	cellular_component	microtubule
W	0005886	cellular_component	plasma membrane
W	0005905	cellular_component	clathrin-coated pit
W	0006897	biological_process	endocytosis
W	0006898	biological_process	receptor-mediated endocytosis
W	0007032	biological_process	endosome organization
W	0008017	molecular_function	microtubule binding
W	0016020	cellular_component	membrane
W	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
W	0016787	molecular_function	hydrolase activity
W	0019003	molecular_function	GDP binding
W	0019901	molecular_function	protein kinase binding
W	0030139	cellular_component	endocytic vesicle
W	0031410	cellular_component	cytoplasmic vesicle
W	0042583	cellular_component	chromaffin granule
W	0042802	molecular_function	identical protein binding
W	0042803	molecular_function	protein homodimerization activity
W	0045202	cellular_component	synapse
W	0051260	biological_process	protein homooligomerization
W	0051289	biological_process	protein homotetramerization
W	0070062	cellular_component	extracellular exosome
W	0097494	biological_process	regulation of vesicle size
W	0098793	cellular_component	presynapse
W	0099049	biological_process	clathrin coat assembly involved in endocytosis
W	0099050	biological_process	vesicle scission
X	0000166	molecular_function	nucleotide binding
X	0003723	molecular_function	RNA binding
X	0003924	molecular_function	GTPase activity
X	0005515	molecular_function	protein binding
X	0005525	molecular_function	GTP binding
X	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
X	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
X	0005737	cellular_component	cytoplasm
X	0005874	cellular_component	microtubule
X	0005886	cellular_component	plasma membrane
X	0005905	cellular_component	clathrin-coated pit
X	0006897	biological_process	endocytosis
X	0006898	biological_process	receptor-mediated endocytosis
X	0007032	biological_process	endosome organization
X	0008017	molecular_function	microtubule binding
X	0016020	cellular_component	membrane
X	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
X	0016787	molecular_function	hydrolase activity
X	0019003	molecular_function	GDP binding
X	0019901	molecular_function	protein kinase binding
X	0030139	cellular_component	endocytic vesicle
X	0031410	cellular_component	cytoplasmic vesicle
X	0042583	cellular_component	chromaffin granule
X	0042802	molecular_function	identical protein binding
X	0042803	molecular_function	protein homodimerization activity
X	0045202	cellular_component	synapse
X	0051260	biological_process	protein homooligomerization
X	0051289	biological_process	protein homotetramerization
X	0070062	cellular_component	extracellular exosome
X	0097494	biological_process	regulation of vesicle size
X	0098793	cellular_component	presynapse
X	0099049	biological_process	clathrin coat assembly involved in endocytosis
X	0099050	biological_process	vesicle scission
Y	0000166	molecular_function	nucleotide binding
Y	0003723	molecular_function	RNA binding
Y	0003924	molecular_function	GTPase activity
Y	0005515	molecular_function	protein binding
Y	0005525	molecular_function	GTP binding
Y	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
Y	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
Y	0005737	cellular_component	cytoplasm
Y	0005874	cellular_component	microtubule
Y	0005886	cellular_component	plasma membrane
Y	0005905	cellular_component	clathrin-coated pit
Y	0006897	biological_process	endocytosis
Y	0006898	biological_process	receptor-mediated endocytosis
Y	0007032	biological_process	endosome organization
Y	0008017	molecular_function	microtubule binding
Y	0016020	cellular_component	membrane
Y	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
Y	0016787	molecular_function	hydrolase activity
Y	0019003	molecular_function	GDP binding
Y	0019901	molecular_function	protein kinase binding
Y	0030139	cellular_component	endocytic vesicle
Y	0031410	cellular_component	cytoplasmic vesicle
Y	0042583	cellular_component	chromaffin granule
Y	0042802	molecular_function	identical protein binding
Y	0042803	molecular_function	protein homodimerization activity
Y	0045202	cellular_component	synapse
Y	0051260	biological_process	protein homooligomerization
Y	0051289	biological_process	protein homotetramerization
Y	0070062	cellular_component	extracellular exosome
Y	0097494	biological_process	regulation of vesicle size
Y	0098793	cellular_component	presynapse
Y	0099049	biological_process	clathrin coat assembly involved in endocytosis
Y	0099050	biological_process	vesicle scission
Z	0000166	molecular_function	nucleotide binding
Z	0003723	molecular_function	RNA binding
Z	0003924	molecular_function	GTPase activity
Z	0005515	molecular_function	protein binding
Z	0005525	molecular_function	GTP binding
Z	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
Z	0005547	molecular_function	phosphatidylinositol-3,4,5-trisphosphate binding
Z	0005737	cellular_component	cytoplasm
Z	0005874	cellular_component	microtubule
Z	0005886	cellular_component	plasma membrane
Z	0005905	cellular_component	clathrin-coated pit
Z	0006897	biological_process	endocytosis
Z	0006898	biological_process	receptor-mediated endocytosis
Z	0007032	biological_process	endosome organization
Z	0008017	molecular_function	microtubule binding
Z	0016020	cellular_component	membrane
Z	0016185	biological_process	synaptic vesicle budding from presynaptic endocytic zone membrane
Z	0016787	molecular_function	hydrolase activity
Z	0019003	molecular_function	GDP binding
Z	0019901	molecular_function	protein kinase binding
Z	0030139	cellular_component	endocytic vesicle
Z	0031410	cellular_component	cytoplasmic vesicle
Z	0042583	cellular_component	chromaffin granule
Z	0042802	molecular_function	identical protein binding
Z	0042803	molecular_function	protein homodimerization activity
Z	0045202	cellular_component	synapse
Z	0051260	biological_process	protein homooligomerization
Z	0051289	biological_process	protein homotetramerization
Z	0070062	cellular_component	extracellular exosome
Z	0097494	biological_process	regulation of vesicle size
Z	0098793	cellular_component	presynapse
Z	0099049	biological_process	clathrin coat assembly involved in endocytosis
Z	0099050	biological_process	vesicle scission

Functional Information from PROSITE/UniProt

site_id	PS00410
Number of Residues	10
Details	G_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGSGIVTR

Chain	Residue	Details
C2	LEU57-ARG66

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9576
Details	Domain: {"description":"Dynamin-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	252
Details	Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	72
Details	Region: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	108
Details	Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	108
Details	Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	108
Details	Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	144
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	180
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30069048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X2F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DLU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2X2F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20428113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26612256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30069048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X2E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5D3Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DLU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	72
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P39053","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	36
Details	Modified residue: {"description":"Phosphotyrosine; alternate","evidences":[{"source":"UniProtKB","id":"P39053","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	36
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P39053","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	36
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P21575","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---