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7AWF

The Fk1 domain of FKBP51 in complex with (2R,5S,12R)-12-cyclohexyl-2-[2-(3,4-dimethoxyphenyl)ethyl]-15,15,16-trimethyl-3,19-dioxa-10,13,16-triazatricyclo[18.3.1.0^5,^10]tetracosa-1(24),20,22-triene-4,11,14,17-tetrone

Functional Information from GO Data
ChainGOidnamespacecontents
A0003755molecular_functionpeptidyl-prolyl cis-trans isomerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue S8N A 201
ChainResidue
ALYS28
AILE87
ATRP90
AALA112
ATYR113
APHE130
AHOH307
AHOH341
AHOH349
AASP30
AARG31
ATYR57
ALYS60
APHE77
AGLY84
AGLN85
AVAL86

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:28147277
ChainResidueDetails
ALYS28

227111

PDB entries from 2024-11-06

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