Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue S5E A 901 |
| Chain | Residue |
| A | LYS619 |
| A | LEU671 |
| A | LEU714 |
| A | HIS721 |
| A | ARG722 |
| A | VAL739 |
| A | ALA740 |
| A | ASP741 |
| A | HOH1012 |
| A | HOH1059 |
| A | MET621 |
| A | GLU630 |
| A | GLU633 |
| A | PHE634 |
| A | GLU637 |
| A | MET641 |
| A | ILE650 |
| A | VAL669 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 902 |
| Chain | Residue |
| A | ARG687 |
| A | HOH1098 |
| B | ARG687 |
| B | MET798 |
| B | HOH1077 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 903 |
| Chain | Residue |
| A | PRO802 |
| A | LYS820 |
| A | HOH1029 |
| A | HOH1040 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 904 |
| Chain | Residue |
| A | HIS817 |
| A | EDO905 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 905 |
| Chain | Residue |
| A | ARG818 |
| A | TYR830 |
| A | EDO904 |
| A | HOH1075 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 906 |
| Chain | Residue |
| A | PRO802 |
| A | TYR812 |
| A | LYS820 |
| A | EDO907 |
| B | TYR685 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 907 |
| Chain | Residue |
| A | GLU808 |
| A | EDO906 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | binding site for residue S5E B 901 |
| Chain | Residue |
| B | LYS619 |
| B | MET621 |
| B | GLU633 |
| B | PHE634 |
| B | GLU637 |
| B | MET641 |
| B | ILE650 |
| B | LEU652 |
| B | VAL669 |
| B | LEU671 |
| B | LEU714 |
| B | HIS721 |
| B | VAL739 |
| B | ALA740 |
| B | ASP741 |
| B | HOH1037 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 902 |
| Chain | Residue |
| A | LEU688 |
| B | PRO802 |
| B | LYS820 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 903 |
| Chain | Residue |
| B | SER645 |
| B | HIS646 |
| B | PRO647 |
| B | EDO904 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 904 |
| Chain | Residue |
| B | SER645 |
| B | TYR713 |
| B | EDO903 |
| B | HOH1033 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGEFGSVMeGnlkqedgtslk.......VAVK |
| Chain | Residue | Details |
| A | LEU593-LYS619 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FLHrDLAARNCML |
| Chain | Residue | Details |
| A | PHE719-LEU731 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
