7AU3
Cytochrome c oxidase structure in F-state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004129 | molecular_function | cytochrome-c oxidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006119 | biological_process | oxidative phosphorylation |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0015990 | biological_process | electron transport coupled proton transport |
| A | 0016020 | cellular_component | membrane |
| A | 0020037 | molecular_function | heme binding |
| A | 0022904 | biological_process | respiratory electron transport chain |
| A | 0045277 | cellular_component | respiratory chain complex IV |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0004129 | molecular_function | cytochrome-c oxidase activity |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0022900 | biological_process | electron transport chain |
| C | 0004129 | molecular_function | cytochrome-c oxidase activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0009060 | biological_process | aerobic respiration |
| C | 0016020 | cellular_component | membrane |
| C | 0019646 | biological_process | aerobic electron transport chain |
| C | 0022904 | biological_process | respiratory electron transport chain |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0004129 | molecular_function | cytochrome-c oxidase activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 55 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyiiilpgfgiishvistfakkpifgylpmvlamaaigilgfvvwa..HH |
| Chain | Residue | Details |
| A | TRP272-HIS326 |
| site_id | PS00078 |
| Number of Residues | 49 |
| Details | COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHawtipafavkqdavpgriaqlwfsvdqegvyfgq......CselCginHayM |
| Chain | Residue | Details |
| B | VAL179-MET227 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 258 |
| Details | Topological domain: {"description":"Periplasmic"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 37 |
| Details | Transmembrane: {"description":"Helical; Name=II"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | Topological domain: {"description":"Cytoplasmic"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=III"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 29 |
| Details | Transmembrane: {"description":"Helical; Name=IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 33 |
| Details | Transmembrane: {"description":"Helical; Name=V"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 36 |
| Details | Transmembrane: {"description":"Helical; Name=VI"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 27 |
| Details | Transmembrane: {"description":"Helical; Name=VII"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 31 |
| Details | Transmembrane: {"description":"Helical; Name=VIII"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=IX"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 32 |
| Details | Transmembrane: {"description":"Helical; Name=X"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 28 |
| Details | Transmembrane: {"description":"Helical; Name=XI"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 35 |
| Details | Transmembrane: {"description":"Helical; Name=XII"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 3 |
| Details | Binding site: {"description":"axial binding residue"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 10 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"1'-histidyl-3'-tyrosine (His-Tyr)"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 263 |
| Details | Transmembrane: {"description":"Helical"} |
| Chain | Residue | Details |
