Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0032787 | biological_process | monocarboxylic acid metabolic process |
| A | 0042183 | biological_process | formate catabolic process |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue NAD A 501 |
| Chain | Residue |
| A | PHE121 |
| A | ASN247 |
| A | THR279 |
| A | PRO280 |
| A | GLN284 |
| A | ASN306 |
| A | ALA307 |
| A | ARG308 |
| A | ASP332 |
| A | HIS356 |
| A | SER358 |
| A | ASN169 |
| A | GLY359 |
| A | GLN400 |
| A | TYR401 |
| A | AZI502 |
| A | HOH617 |
| A | HOH627 |
| A | HOH631 |
| A | HOH651 |
| A | HOH653 |
| A | HOH660 |
| A | VAL170 |
| A | VAL173 |
| A | GLY223 |
| A | ARG224 |
| A | ILE225 |
| A | ASP245 |
| A | ARG246 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue AZI A 502 |
| Chain | Residue |
| A | PRO120 |
| A | PHE121 |
| A | GLY144 |
| A | VAL145 |
| A | ASN169 |
| A | ARG308 |
| A | HIS356 |
| A | NAD501 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue AZI A 503 |
| Chain | Residue |
| A | LEU116 |
| A | THR118 |
| A | LEU140 |
| A | VAL141 |
| A | THR142 |
| A | VAL162 |
| A | SER163 |
Functional Information from PROSITE/UniProt
| site_id | PS00065 |
| Number of Residues | 29 |
| Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGTVGgGRIGqelmkrlkgfglkeMLyYD |
| Chain | Residue | Details |
| A | VAL217-ASP245 | |
| site_id | PS00670 |
| Number of Residues | 23 |
| Details | D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. MLskCDVVvVNtPltdqTrgLfN |
| Chain | Residue | Details |
| A | MET268-ASN290 | |
