7AOB
Crystal structure of Thermaerobacter marianensis malate dehydrogenase
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004459 | molecular_function | L-lactate dehydrogenase activity |
A | 0006089 | biological_process | lactate metabolic process |
A | 0006090 | biological_process | pyruvate metabolic process |
A | 0006099 | biological_process | tricarboxylic acid cycle |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
A | 0019752 | biological_process | carboxylic acid metabolic process |
A | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004459 | molecular_function | L-lactate dehydrogenase activity |
B | 0006089 | biological_process | lactate metabolic process |
B | 0006090 | biological_process | pyruvate metabolic process |
B | 0006099 | biological_process | tricarboxylic acid cycle |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
B | 0019752 | biological_process | carboxylic acid metabolic process |
B | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004459 | molecular_function | L-lactate dehydrogenase activity |
C | 0006089 | biological_process | lactate metabolic process |
C | 0006090 | biological_process | pyruvate metabolic process |
C | 0006099 | biological_process | tricarboxylic acid cycle |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
C | 0019752 | biological_process | carboxylic acid metabolic process |
C | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
D | 0003824 | molecular_function | catalytic activity |
D | 0004459 | molecular_function | L-lactate dehydrogenase activity |
D | 0006089 | biological_process | lactate metabolic process |
D | 0006090 | biological_process | pyruvate metabolic process |
D | 0006099 | biological_process | tricarboxylic acid cycle |
D | 0016491 | molecular_function | oxidoreductase activity |
D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
D | 0019752 | biological_process | carboxylic acid metabolic process |
D | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue GOL A 401 |
Chain | Residue |
A | ALA158 |
D | HOH666 |
A | ARG159 |
A | ASN162 |
A | VAL163 |
A | PHE165 |
B | ARG3 |
B | ASP57 |
D | ASP244 |
D | ARG245 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue PEG A 402 |
Chain | Residue |
A | GLN41 |
A | GLY62 |
A | HOH563 |
A | HOH637 |
A | HOH697 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue 1PE A 403 |
Chain | Residue |
A | ARG159 |
A | HOH515 |
A | HOH689 |
A | HOH704 |
A | HOH715 |
B | ASP29 |
B | VAL59 |
B | THR61 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue PEG A 404 |
Chain | Residue |
A | ASP34 |
A | VAL35 |
A | ILE99 |
A | HOH555 |
A | HOH587 |
A | HOH658 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue GOL A 405 |
Chain | Residue |
A | ASN13 |
A | ALA16 |
A | HOH501 |
A | HOH533 |
B | ASN13 |
B | HOH586 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue GOL A 406 |
Chain | Residue |
A | GLY10 |
A | GLY12 |
A | ASN13 |
A | THR14 |
A | GLY15 |
A | THR78 |
site_id | AC7 |
Number of Residues | 5 |
Details | binding site for residue GOL A 407 |
Chain | Residue |
A | GLU258 |
A | LYS279 |
A | ILE280 |
A | GLU282 |
A | HOH645 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue EDO A 408 |
Chain | Residue |
A | GLY80 |
A | LEU119 |
A | ASN121 |
site_id | AC9 |
Number of Residues | 9 |
Details | binding site for residue GOL B 401 |
Chain | Residue |
A | ARG3 |
A | ASP57 |
B | ALA158 |
B | ARG159 |
B | ASN162 |
B | VAL163 |
B | HOH570 |
C | ASP244 |
C | ARG245 |
site_id | AD1 |
Number of Residues | 11 |
Details | binding site for residue GOL C 401 |
Chain | Residue |
B | ASP244 |
B | ARG245 |
C | ALA158 |
C | ARG159 |
C | ASN162 |
C | VAL163 |
C | PHE165 |
C | HOH550 |
C | HOH601 |
D | ARG3 |
D | ASP57 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue PGE C 402 |
Chain | Residue |
C | ARG159 |
C | ARG209 |
C | HOH545 |
C | HOH565 |
C | HOH598 |
D | THR61 |
site_id | AD3 |
Number of Residues | 10 |
Details | binding site for residue GOL D 401 |
Chain | Residue |
A | ASP244 |
A | ARG245 |
C | ARG3 |
C | ASP57 |
D | ALA158 |
D | ARG159 |
D | ASN162 |
D | VAL163 |
D | PHE165 |
D | HOH670 |
site_id | AD4 |
Number of Residues | 5 |
Details | binding site for residue GOL D 402 |
Chain | Residue |
D | THR78 |
D | GLY80 |
D | THR120 |
D | ASN121 |
D | HOH683 |
site_id | AD5 |
Number of Residues | 7 |
Details | binding site for residue GOL D 403 |
Chain | Residue |
C | ASN13 |
C | HOH531 |
D | ASN13 |
D | ALA16 |
D | ALA17 |
D | HOH505 |
D | HOH570 |