7ANC
MlghC, GDP-mannoheptose C4 reductase from Campylobacter jejuni with NADP bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0009226 | biological_process | nucleotide-sugar biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0042351 | biological_process | 'de novo' GDP-L-fucose biosynthetic process |
| A | 0050577 | molecular_function | GDP-L-fucose synthase activity |
| A | 0070401 | molecular_function | NADP+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0009226 | biological_process | nucleotide-sugar biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0042351 | biological_process | 'de novo' GDP-L-fucose biosynthetic process |
| B | 0050577 | molecular_function | GDP-L-fucose synthase activity |
| B | 0070401 | molecular_function | NADP+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue NAP A 401 |
| Chain | Residue |
| A | LYS13 |
| A | THR63 |
| A | ALA64 |
| A | VAL65 |
| A | PHE105 |
| A | GLY106 |
| A | LYS140 |
| A | LEU163 |
| A | ASN164 |
| A | LEU166 |
| A | HOH510 |
| A | GLY14 |
| A | HOH536 |
| A | HOH547 |
| A | HOH568 |
| A | HOH607 |
| A | HOH639 |
| A | THR15 |
| A | ALA16 |
| A | ARG37 |
| A | LEU40 |
| A | ASP41 |
| A | LEU42 |
| A | VAL43 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | binding site for residue NAP B 401 |
| Chain | Residue |
| B | GLY14 |
| B | THR15 |
| B | ALA16 |
| B | ARG37 |
| B | LEU40 |
| B | ASP41 |
| B | LEU42 |
| B | THR63 |
| B | ALA64 |
| B | VAL65 |
| B | PHE105 |
| B | GLY106 |
| B | LYS140 |
| B | LEU163 |
| B | ASN164 |
| B | ASN165 |
| B | LEU166 |
| B | ARG179 |
| B | HOH501 |
| B | HOH511 |
| B | HOH512 |
| B | HOH533 |
| B | HOH539 |
| B | HOH556 |
| B | HOH566 |
| B | HOH596 |
| B | HOH598 |
