7AM0
GqqA- a novel type of quorum quenching acylases
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004664 | molecular_function | prephenate dehydratase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009094 | biological_process | L-phenylalanine biosynthetic process |
| A | 0009372 | biological_process | quorum sensing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004664 | molecular_function | prephenate dehydratase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009094 | biological_process | L-phenylalanine biosynthetic process |
| B | 0009372 | biological_process | quorum sensing |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004664 | molecular_function | prephenate dehydratase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009094 | biological_process | L-phenylalanine biosynthetic process |
| C | 0009372 | biological_process | quorum sensing |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016829 | molecular_function | lyase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004664 | molecular_function | prephenate dehydratase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009094 | biological_process | L-phenylalanine biosynthetic process |
| D | 0009372 | biological_process | quorum sensing |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue PHE A 301 |
| Chain | Residue |
| A | ASN202 |
| B | ASN221 |
| B | MET222 |
| B | THR223 |
| B | ARG224 |
| A | ASN203 |
| A | GLN204 |
| A | GLY206 |
| A | ALA207 |
| A | LEU208 |
| A | THR237 |
| A | PHE239 |
| A | HOH404 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue PHE B 301 |
| Chain | Residue |
| A | ASN221 |
| A | MET222 |
| A | THR223 |
| A | ARG224 |
| B | ASN202 |
| B | ASN203 |
| B | GLN204 |
| B | PRO205 |
| B | ALA207 |
| B | LEU208 |
| B | THR237 |
| B | PHE239 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue PHE C 301 |
| Chain | Residue |
| C | ASN202 |
| C | ASN203 |
| C | GLN204 |
| C | GLY206 |
| C | ALA207 |
| C | LEU208 |
| C | THR237 |
| C | PHE239 |
| D | ASN221 |
| D | MET222 |
| D | THR223 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue PHE D 301 |
| Chain | Residue |
| C | ASN221 |
| C | MET222 |
| C | THR223 |
| C | ARG224 |
| D | ASN202 |
| D | ASN203 |
| D | GLN204 |
| D | ALA207 |
| D | LEU208 |
| D | THR237 |
| D | PHE239 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 525 |
| Details | Domain: {"description":"Prephenate dehydratase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00517","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 308 |
| Details | Domain: {"description":"ACT","evidences":[{"source":"PROSITE-ProRule","id":"PRU01007","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34112823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7ALZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7AM0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for prephenate dehydratase activity","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
