7ALP

Severe fever with thrombocytopenia syndrome virus (Phenuiviridae) L protein

Functional Information from GO Data

Chain	GOid	namespace	contents
U	0001172	biological_process	RNA-templated transcription
U	0003968	molecular_function	RNA-directed RNA polymerase activity
U	0006351	biological_process	DNA-templated transcription
U	0016740	molecular_function	transferase activity
U	0016787	molecular_function	hydrolase activity
U	0019079	biological_process	viral genome replication
U	0039694	biological_process	viral RNA genome replication
U	0044165	cellular_component	host cell endoplasmic reticulum
U	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
U	0044177	cellular_component	host cell Golgi apparatus
U	0044423	cellular_component	virion component
U	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	115
Details	Region: {"description":"Cap-binding","evidences":[{"source":"PubMed","id":"32313945","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32341479","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"For endonuclease activity","evidences":[{"source":"PubMed","id":"31914382","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"A5HC98","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32313945","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32341479","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Site: {"description":"Interaction with the cap substrate","evidences":[{"source":"UniProtKB","id":"A2SZS3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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