7AL8

Structure of ATSI with bovine trypsin

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0004175	molecular_function	endopeptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006508	biological_process	proteolysis
B	0007586	biological_process	digestion
B	0008233	molecular_function	peptidase activity
B	0008236	molecular_function	serine-type peptidase activity
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
B	0097180	cellular_component	serine protease inhibitor complex
B	0097655	molecular_function	serpin family protein binding
C	0004867	molecular_function	serine-type endopeptidase inhibitor activity
C	0009611	biological_process	response to wounding
C	0030414	molecular_function	peptidase inhibitor activity
E	0004175	molecular_function	endopeptidase activity
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0006508	biological_process	proteolysis
E	0007586	biological_process	digestion
E	0008233	molecular_function	peptidase activity
E	0008236	molecular_function	serine-type peptidase activity
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
E	0097180	cellular_component	serine protease inhibitor complex
E	0097655	molecular_function	serpin family protein binding
F	0004867	molecular_function	serine-type endopeptidase inhibitor activity
F	0009611	biological_process	response to wounding
F	0030414	molecular_function	peptidase inhibitor activity
H	0004175	molecular_function	endopeptidase activity
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0006508	biological_process	proteolysis
H	0007586	biological_process	digestion
H	0008233	molecular_function	peptidase activity
H	0008236	molecular_function	serine-type peptidase activity
H	0016787	molecular_function	hydrolase activity
H	0046872	molecular_function	metal ion binding
H	0097180	cellular_component	serine protease inhibitor complex
H	0097655	molecular_function	serpin family protein binding
I	0004867	molecular_function	serine-type endopeptidase inhibitor activity
I	0009611	biological_process	response to wounding
I	0030414	molecular_function	peptidase inhibitor activity
K	0004175	molecular_function	endopeptidase activity
K	0004252	molecular_function	serine-type endopeptidase activity
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005615	cellular_component	extracellular space
K	0006508	biological_process	proteolysis
K	0007586	biological_process	digestion
K	0008233	molecular_function	peptidase activity
K	0008236	molecular_function	serine-type peptidase activity
K	0016787	molecular_function	hydrolase activity
K	0046872	molecular_function	metal ion binding
K	0097180	cellular_component	serine protease inhibitor complex
K	0097655	molecular_function	serpin family protein binding
L	0004867	molecular_function	serine-type endopeptidase inhibitor activity
L	0009611	biological_process	response to wounding
L	0030414	molecular_function	peptidase inhibitor activity
N	0004175	molecular_function	endopeptidase activity
N	0004252	molecular_function	serine-type endopeptidase activity
N	0005515	molecular_function	protein binding
N	0005576	cellular_component	extracellular region
N	0005615	cellular_component	extracellular space
N	0006508	biological_process	proteolysis
N	0007586	biological_process	digestion
N	0008233	molecular_function	peptidase activity
N	0008236	molecular_function	serine-type peptidase activity
N	0016787	molecular_function	hydrolase activity
N	0046872	molecular_function	metal ion binding
N	0097180	cellular_component	serine protease inhibitor complex
N	0097655	molecular_function	serpin family protein binding
O	0004867	molecular_function	serine-type endopeptidase inhibitor activity
O	0009611	biological_process	response to wounding
O	0030414	molecular_function	peptidase inhibitor activity
Q	0004175	molecular_function	endopeptidase activity
Q	0004252	molecular_function	serine-type endopeptidase activity
Q	0005515	molecular_function	protein binding
Q	0005576	cellular_component	extracellular region
Q	0005615	cellular_component	extracellular space
Q	0006508	biological_process	proteolysis
Q	0007586	biological_process	digestion
Q	0008233	molecular_function	peptidase activity
Q	0008236	molecular_function	serine-type peptidase activity
Q	0016787	molecular_function	hydrolase activity
Q	0046872	molecular_function	metal ion binding
Q	0097180	cellular_component	serine protease inhibitor complex
Q	0097655	molecular_function	serpin family protein binding
R	0004867	molecular_function	serine-type endopeptidase inhibitor activity
R	0009611	biological_process	response to wounding
R	0030414	molecular_function	peptidase inhibitor activity
T	0004175	molecular_function	endopeptidase activity
T	0004252	molecular_function	serine-type endopeptidase activity
T	0005515	molecular_function	protein binding
T	0005576	cellular_component	extracellular region
T	0005615	cellular_component	extracellular space
T	0006508	biological_process	proteolysis
T	0007586	biological_process	digestion
T	0008233	molecular_function	peptidase activity
T	0008236	molecular_function	serine-type peptidase activity
T	0016787	molecular_function	hydrolase activity
T	0046872	molecular_function	metal ion binding
T	0097180	cellular_component	serine protease inhibitor complex
T	0097655	molecular_function	serpin family protein binding
U	0004175	molecular_function	endopeptidase activity
U	0004252	molecular_function	serine-type endopeptidase activity
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005615	cellular_component	extracellular space
U	0006508	biological_process	proteolysis
U	0007586	biological_process	digestion
U	0008233	molecular_function	peptidase activity
U	0008236	molecular_function	serine-type peptidase activity
U	0016787	molecular_function	hydrolase activity
U	0046872	molecular_function	metal ion binding
U	0097180	cellular_component	serine protease inhibitor complex
U	0097655	molecular_function	serpin family protein binding
V	0004867	molecular_function	serine-type endopeptidase inhibitor activity
V	0009611	biological_process	response to wounding
V	0030414	molecular_function	peptidase inhibitor activity
X	0004867	molecular_function	serine-type endopeptidase inhibitor activity
X	0009611	biological_process	response to wounding
X	0030414	molecular_function	peptidase inhibitor activity

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC

Chain	Residue	Details
U	VAL59-CYS64

---

site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV

Chain	Residue	Details
U	ASP194-VAL205

---

site_id	PS00285
Number of Residues	12
Details	POTATO_INHIBITOR Potato inhibitor I family signature. WPELVGeyGykA

Chain	Residue	Details
X	TRP9-ALA20

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1760
Details	Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Active site: {"description":"Charge relay system"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	56
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Site: {"description":"Reactive bond","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---