7AHH
OpuA inhibited inward-facing, SBD docked
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005275 | molecular_function | amine transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015226 | molecular_function | carnitine transmembrane transporter activity |
| A | 0015837 | biological_process | amine transport |
| A | 0015871 | biological_process | choline transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0031460 | biological_process | glycine betaine transport |
| A | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| A | 0055085 | biological_process | transmembrane transport |
| A | 1902603 | biological_process | carnitine transmembrane transport |
| B | 0005275 | molecular_function | amine transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015226 | molecular_function | carnitine transmembrane transporter activity |
| B | 0015837 | biological_process | amine transport |
| B | 0015871 | biological_process | choline transport |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0031460 | biological_process | glycine betaine transport |
| B | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| B | 0055085 | biological_process | transmembrane transport |
| B | 1902603 | biological_process | carnitine transmembrane transport |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006970 | biological_process | response to osmotic stress |
| C | 0015418 | molecular_function | ABC-type quaternary ammonium compound transporting activity |
| C | 0016020 | cellular_component | membrane |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0031460 | biological_process | glycine betaine transport |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006970 | biological_process | response to osmotic stress |
| D | 0015418 | molecular_function | ABC-type quaternary ammonium compound transporting activity |
| D | 0016020 | cellular_component | membrane |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0031460 | biological_process | glycine betaine transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue BET A 601 |
| Chain | Residue |
| A | TRP330 |
| A | TRP377 |
| A | THR381 |
| A | HIS382 |
| A | ALA436 |
| A | GLY437 |
| A | VAL438 |
| A | TRP484 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue ANP C 501 |
| Chain | Residue |
| C | LYS31 |
| C | THR41 |
| C | VAL42 |
| C | GLY43 |
| C | LEU62 |
| C | SER63 |
| C | GLY64 |
| C | SER65 |
| C | GLY66 |
| C | LYS67 |
| C | SER68 |
| C | THR69 |
| C | ASP189 |
| C | GLU190 |
| C | PHE14 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue ANP D 501 |
| Chain | Residue |
| D | PHE14 |
| D | LYS31 |
| D | THR41 |
| D | VAL42 |
| D | GLY43 |
| D | LEU62 |
| D | SER63 |
| D | GLY64 |
| D | SER65 |
| D | GLY66 |
| D | LYS67 |
| D | SER68 |
| D | THR69 |
| D | ASP189 |
| D | GLU190 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue 2BA D 502 |
| Chain | Residue |
| C | ILE281 |
| C | LEU284 |
| C | GLU304 |
| C | SER306 |
| C | SER307 |
| C | PRO366 |
| D | PRO282 |
| D | LEU284 |
| D | VAL305 |
| D | SER306 |
| D | SER307 |
| D | PRO366 |
| D | ILE381 |
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSGGMQQRVGLARAL |
| Chain | Residue | Details |
| C | LEU165-LEU179 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI4 |
| Number of Residues | 520 |
| Details | Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 112 |
| Details | Domain: {"description":"CBS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
