Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7ADH

THREE-DIMENSIONAL STRUCTURE OF ISONICOTINIMIDYLATED LIVER ALCOHOL DEHYDROGENASE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
A	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0042572	biological_process	retinol metabolic process
A	0042573	biological_process	retinoic acid metabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 375

Chain	Residue
A	CYS46
A	SER48
A	HIS67
A	CYS174

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ZN A 376

Chain	Residue
A	PHE319
A	PHE322
A	LYS323
A	SER324
A	CYS97
A	CYS100
A	CYS103
A	ASN109
A	CYS111

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NTN A 377

Chain	Residue
A	LYS5
A	VAL41
A	ALA42
A	ALA70
A	LEU166
A	GLU167
A	LYS168
A	CYS170

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NTN A 378

Chain	Residue
A	LYS8
A	VAL28
A	ALA29
A	ARG37
A	ILE38
A	ARG129
A	TYR149
A	THR150
A	VAL151

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE NTN A 379

Chain	Residue
A	LYS10
A	VAL13
A	TRP15
A	SER22
A	GLU24
A	GLU25
A	VAL26
A	THR131
A	CYS132
A	ILE137

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NTN A 380

Chain	Residue
A	LYS18
A	SER54

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NTN A 381

Chain	Residue
A	LYS19
A	NTN387

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NTN A 382

Chain	Residue
A	LYS32
A	LEU279
A	CYS282
A	GLY287
A	VAL288
A	SER289
A	ARG312
A	THR313

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE NTN A 383

Chain	Residue
A	THR2
A	ALA3
A	GLY4
A	LYS5
A	VAL6
A	ILE7
A	PRO30
A	ARG37
A	LYS39
A	GLU74

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NTN A 384

Chain	Residue
A	LYS88
A	ALA163

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NTN A 385

Chain	Residue
A	ILE90
A	LYS99
A	ILE172
A	PHE176
A	SER177
A	VAL328
A	LEU331

site_id	BC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE NTN A 386

Chain	Residue
A	LYS113
A	GLN124
A	SER177
A	THR178
A	GLY179
A	GLY181
A	SER182
A	VAL186
A	ALA317
A	PHE319
A	GLY320
A	GLY321

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NTN A 387

Chain	Residue
A	LYS135
A	NTN381

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NTN A 388

Chain	Residue
A	ASP87
A	LYS159

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NTN A 389

Chain	Residue
A	LYS168
A	ILE346
A	VAL349

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NTN A 390

Chain	Residue
A	LYS185
A	NTN397
A	NTN398

site_id	BC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NTN A 391

Chain	Residue
A	VAL80
A	LYS188
A	LYS315
A	LYS32
A	ALA33
A	HIS34
A	GLU35
A	VAL36
A	GLU78

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NTN A 392

Chain	Residue
A	LYS212

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NTN A 393

Chain	Residue
A	LYS226

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NTN A 394

Chain	Residue
A	LYS228

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NTN A 395

Chain	Residue
A	LYS228
A	LYS231
A	GLU366
A	ILE368

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NTN A 396

Chain	Residue
A	LYS247

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NTN A 397

Chain	Residue
A	THR82
A	PRO106
A	LYS185
A	LYS325
A	NTN390

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NTN A 398

Chain	Residue
A	GLY98
A	ASP326
A	LYS330
A	NTN390

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NTN A 399

Chain	Residue
A	MET306
A	LYS354
A	GLU357

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaAGIvesiGegV

Chain	Residue	Details
A	GLY66-VAL80

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P06525","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"5466062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
A	LEU57

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1guf

Chain	Residue	Details
A	SER48
A	HIS51

site_id	MCSA1
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
A	CYS46	metal ligand
A	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS67	metal ligand
A	CYS174	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)