Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7ABH

Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000398	biological_process	mRNA splicing, via spliceosome
0	0003723	molecular_function	RNA binding
0	0003729	molecular_function	mRNA binding
0	0005515	molecular_function	protein binding
0	0005634	cellular_component	nucleus
0	0005654	cellular_component	nucleoplasm
0	0005681	cellular_component	spliceosomal complex
0	0005686	cellular_component	U2 snRNP
0	0005829	cellular_component	cytosol
0	0006397	biological_process	mRNA processing
0	0008380	biological_process	RNA splicing
0	0031047	biological_process	regulatory ncRNA-mediated gene silencing
0	0035196	biological_process	miRNA processing
0	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
0	0071005	cellular_component	U2-type precatalytic spliceosome
0	0140416	molecular_function	transcription regulator inhibitor activity
0	1903241	biological_process	U2-type prespliceosome assembly
1	0000398	biological_process	mRNA splicing, via spliceosome
1	0003676	molecular_function	nucleic acid binding
1	0003723	molecular_function	RNA binding
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005654	cellular_component	nucleoplasm
1	0005681	cellular_component	spliceosomal complex
1	0005686	cellular_component	U2 snRNP
1	0005730	cellular_component	nucleolus
1	0005783	cellular_component	endoplasmic reticulum
1	0006397	biological_process	mRNA processing
1	0008380	biological_process	RNA splicing
1	0031965	cellular_component	nuclear membrane
1	0071005	cellular_component	U2-type precatalytic spliceosome
1	0071011	cellular_component	precatalytic spliceosome
1	1903241	biological_process	U2-type prespliceosome assembly
4	0000375	biological_process	RNA splicing, via transesterification reactions
4	0000389	biological_process	mRNA 3'-splice site recognition
4	0000398	biological_process	mRNA splicing, via spliceosome
4	0003676	molecular_function	nucleic acid binding
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005681	cellular_component	spliceosomal complex
4	0005684	cellular_component	U2-type spliceosomal complex
4	0005686	cellular_component	U2 snRNP
4	0006397	biological_process	mRNA processing
4	0008270	molecular_function	zinc ion binding
4	0008380	biological_process	RNA splicing
4	0016607	cellular_component	nuclear speck
4	0046872	molecular_function	metal ion binding
4	0071005	cellular_component	U2-type precatalytic spliceosome
4	0071013	cellular_component	catalytic step 2 spliceosome
4	1903241	biological_process	U2-type prespliceosome assembly
7	0003677	molecular_function	DNA binding
7	0003690	molecular_function	double-stranded DNA binding
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005737	cellular_component	cytoplasm
7	0006260	biological_process	DNA replication
7	0006281	biological_process	DNA repair
7	0006310	biological_process	DNA recombination
7	0006397	biological_process	mRNA processing
7	0006974	biological_process	DNA damage response
7	0016363	cellular_component	nuclear matrix
7	0032991	cellular_component	protein-containing complex
7	0043231	cellular_component	intracellular membrane-bounded organelle
7	0046872	molecular_function	metal ion binding
E	0000124	cellular_component	SAGA complex
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003676	molecular_function	nucleic acid binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005684	cellular_component	U2-type spliceosomal complex
E	0005686	cellular_component	U2 snRNP
E	0005689	cellular_component	U12-type spliceosomal complex
E	0005730	cellular_component	nucleolus
E	0006282	biological_process	regulation of DNA repair
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0030620	molecular_function	U2 snRNA binding
E	0042177	biological_process	negative regulation of protein catabolic process
E	0043484	biological_process	regulation of RNA splicing
E	0044877	molecular_function	protein-containing complex binding
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0071005	cellular_component	U2-type precatalytic spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	1903241	biological_process	U2-type prespliceosome assembly
F	0000245	biological_process	spliceosomal complex assembly
F	0000389	biological_process	mRNA 3'-splice site recognition
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005684	cellular_component	U2-type spliceosomal complex
F	0005686	cellular_component	U2 snRNP
F	0006397	biological_process	mRNA processing
F	0008270	molecular_function	zinc ion binding
F	0008380	biological_process	RNA splicing
F	0010976	biological_process	positive regulation of neuron projection development
F	0016607	cellular_component	nuclear speck
F	0046872	molecular_function	metal ion binding
F	0071004	cellular_component	U2-type prespliceosome
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	0071013	cellular_component	catalytic step 2 spliceosome
F	1903241	biological_process	U2-type prespliceosome assembly
L	0000077	biological_process	DNA damage checkpoint signaling
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005662	cellular_component	DNA replication factor A complex
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0006281	biological_process	DNA repair
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0016020	cellular_component	membrane
L	0016607	cellular_component	nuclear speck
L	0042802	molecular_function	identical protein binding
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	0071013	cellular_component	catalytic step 2 spliceosome
L	0071987	molecular_function	WD40-repeat domain binding
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005681	cellular_component	spliceosomal complex
T	0005684	cellular_component	U2-type spliceosomal complex
T	0005686	cellular_component	U2 snRNP
T	0005689	cellular_component	U12-type spliceosomal complex
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016607	cellular_component	nuclear speck
T	0071005	cellular_component	U2-type precatalytic spliceosome
T	0071011	cellular_component	precatalytic spliceosome
T	0071013	cellular_component	catalytic step 2 spliceosome
T	1903241	biological_process	U2-type prespliceosome assembly
Y	0000375	biological_process	RNA splicing, via transesterification reactions
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0003677	molecular_function	DNA binding
Y	0003723	molecular_function	RNA binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005681	cellular_component	spliceosomal complex
Y	0005829	cellular_component	cytosol
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0016363	cellular_component	nuclear matrix
Y	0016607	cellular_component	nuclear speck
Y	0048024	biological_process	regulation of mRNA splicing, via spliceosome
Y	0071013	cellular_component	catalytic step 2 spliceosome
u	0000245	biological_process	spliceosomal complex assembly
u	0000375	biological_process	RNA splicing, via transesterification reactions
u	0000398	biological_process	mRNA splicing, via spliceosome
u	0003723	molecular_function	RNA binding
u	0003729	molecular_function	mRNA binding
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005681	cellular_component	spliceosomal complex
u	0005684	cellular_component	U2-type spliceosomal complex
u	0005686	cellular_component	U2 snRNP
u	0005689	cellular_component	U12-type spliceosomal complex
u	0005730	cellular_component	nucleolus
u	0006338	biological_process	chromatin remodeling
u	0006397	biological_process	mRNA processing
u	0008380	biological_process	RNA splicing
u	0016607	cellular_component	nuclear speck
u	0034693	cellular_component	U11/U12 snRNP
u	0045943	biological_process	positive regulation of transcription by RNA polymerase I
u	0045944	biological_process	positive regulation of transcription by RNA polymerase II
u	0045945	biological_process	positive regulation of transcription by RNA polymerase III
u	0071004	cellular_component	U2-type prespliceosome
u	0071005	cellular_component	U2-type precatalytic spliceosome
u	0071013	cellular_component	catalytic step 2 spliceosome
u	0110016	cellular_component	B-WICH complex
u	1903241	biological_process	U2-type prespliceosome assembly
u	1990935	molecular_function	splicing factor binding
w	0000375	biological_process	RNA splicing, via transesterification reactions
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0003676	molecular_function	nucleic acid binding
w	0003723	molecular_function	RNA binding
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005681	cellular_component	spliceosomal complex
w	0005684	cellular_component	U2-type spliceosomal complex
w	0005686	cellular_component	U2 snRNP
w	0005689	cellular_component	U12-type spliceosomal complex
w	0006397	biological_process	mRNA processing
w	0008380	biological_process	RNA splicing
w	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
w	0071005	cellular_component	U2-type precatalytic spliceosome
w	1903241	biological_process	U2-type prespliceosome assembly
w	1990935	molecular_function	splicing factor binding
x	0000124	cellular_component	SAGA complex
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0003723	molecular_function	RNA binding
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005681	cellular_component	spliceosomal complex
x	0005684	cellular_component	U2-type spliceosomal complex
x	0005686	cellular_component	U2 snRNP
x	0005689	cellular_component	U12-type spliceosomal complex
x	0006282	biological_process	regulation of DNA repair
x	0006397	biological_process	mRNA processing
x	0008380	biological_process	RNA splicing
x	0043484	biological_process	regulation of RNA splicing
x	0045893	biological_process	positive regulation of DNA-templated transcription
x	0071005	cellular_component	U2-type precatalytic spliceosome
x	0071011	cellular_component	precatalytic spliceosome
x	1903241	biological_process	U2-type prespliceosome assembly
x	1990935	molecular_function	splicing factor binding
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0003677	molecular_function	DNA binding
y	0003723	molecular_function	RNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0005684	cellular_component	U2-type spliceosomal complex
y	0005686	cellular_component	U2 snRNP
y	0005689	cellular_component	U12-type spliceosomal complex
y	0006397	biological_process	mRNA processing
y	0008270	molecular_function	zinc ion binding
y	0008380	biological_process	RNA splicing
y	0016363	cellular_component	nuclear matrix
y	0016607	cellular_component	nuclear speck
y	0045893	biological_process	positive regulation of DNA-templated transcription
y	0046872	molecular_function	metal ion binding
y	0048863	biological_process	stem cell differentiation
y	0071005	cellular_component	U2-type precatalytic spliceosome
y	0071011	cellular_component	precatalytic spliceosome
y	1903241	biological_process	U2-type prespliceosome assembly
z	0000398	biological_process	mRNA splicing, via spliceosome
z	0001825	biological_process	blastocyst formation
z	0003676	molecular_function	nucleic acid binding
z	0003723	molecular_function	RNA binding
z	0003729	molecular_function	mRNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0005681	cellular_component	spliceosomal complex
z	0005684	cellular_component	U2-type spliceosomal complex
z	0005686	cellular_component	U2 snRNP
z	0005689	cellular_component	U12-type spliceosomal complex
z	0006397	biological_process	mRNA processing
z	0008380	biological_process	RNA splicing
z	0071011	cellular_component	precatalytic spliceosome
z	0071013	cellular_component	catalytic step 2 spliceosome
z	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
E	PHE287-HIS293

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cqm..CqkqCrdengfkcHcmsesH

Chain	Residue	Details
7	CYS28-HIS50

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	ZN_FING: C2H2-type => ECO:0000255

Chain	Residue	Details
7	CYS28-HIS50
E	GLU352
E	ARG429
E	ASN916
y	CYS46
y	CYS49
y	CYS58
y	CYS61
y	CYS72
y	CYS75
y	CYS85
x	GLY20

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-methyllysine => ECO:0007744\|PubMed:24129315

Chain	Residue	Details
7	LYS135
E	LYS1171

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
u	GLU1205
Y	LYS140
u	CYS677

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19367720, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	THR235
u	THR426
Y	THR220

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231

Chain	Residue	Details
1	SER272
1	SER314
Y	SER227

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
0	SER202
1	LYS243
Y	SER234

site_id	SWS_FT_FI7
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER797
Y	SER240
Y	SER802

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
T	SER362
Y	THR241

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
T	SER436
Y	SER260
T	SER435

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269\|Ref.5, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER389
0	LYS223

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER391

site_id	SWS_FT_FI12
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269\|Ref.5, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER393
L	THR438
T	LYS280
T	LYS492
T	LYS543
T	LYS770
T	LYS790
T	LYS843
T	LYS857

site_id	SWS_FT_FI13
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:15144186, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER402

site_id	SWS_FT_FI14
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:15144186, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	THR406

site_id	SWS_FT_FI15
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692

Chain	Residue	Details
Y	SER414
Y	SER583
Y	SER420
Y	SER707
Y	SER795

site_id	SWS_FT_FI16
Number of Residues	6
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:21406692

Chain	Residue	Details
Y	THR416
Y	THR555
Y	THR572
Y	THR574
Y	THR581
Y	THR793

site_id	SWS_FT_FI17
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER429
Y	SER431
Y	SER605
Y	SER607

site_id	SWS_FT_FI18
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
Y	SER436
Y	SER777

site_id	SWS_FT_FI19
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:17924679, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER450
u	THR261
u	THR278
u	THR303
u	THR313

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:17924679, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER452

site_id	SWS_FT_FI21
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER463
Y	SER465

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:20068231

Chain	Residue	Details
Y	SER478

site_id	SWS_FT_FI23
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER524
Y	SER526
Y	SER528
Y	SER530
Y	SER532
Y	SER773
Y	SER901

site_id	SWS_FT_FI24
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER549
Y	SER551
Y	SER705

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER560
Y	SER562

site_id	SWS_FT_FI26
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	TYR596

site_id	SWS_FT_FI27
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER597

site_id	SWS_FT_FI28
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	THR614

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER616

site_id	SWS_FT_FI30
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
Y	SER626
Y	SER628

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
Y	SER636

site_id	SWS_FT_FI32
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	THR436
Y	SER638

site_id	SWS_FT_FI33
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER694
Y	SER715
Y	SER748

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:Q52KI8

Chain	Residue	Details
Y	SER695

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER696

site_id	SWS_FT_FI36
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER713

site_id	SWS_FT_FI37
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	THR718

site_id	SWS_FT_FI38
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	LYS430
Y	SER738

site_id	SWS_FT_FI39
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER740

site_id	SWS_FT_FI40
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER752

site_id	SWS_FT_FI41
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER754
Y	SER756

site_id	SWS_FT_FI42
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER769

site_id	SWS_FT_FI43
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER775

site_id	SWS_FT_FI44
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:Q52KI8

Chain	Residue	Details
Y	THR778

site_id	SWS_FT_FI45
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER781

site_id	SWS_FT_FI46
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER791

site_id	SWS_FT_FI47
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18318008, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	THR872

site_id	SWS_FT_FI48
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18318008, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER874

site_id	SWS_FT_FI49
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	LYS127
Y	LYS447
Y	LYS459
Y	LYS472
Y	LYS869

site_id	SWS_FT_FI50
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	LYS231

site_id	SWS_FT_FI51
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	LYS249

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)