7A7B
Bacillithiol Disulfide Reductase Bdr (YpdA) from Staphylococcus aureus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0045454 | biological_process | cell redox homeostasis |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0045454 | biological_process | cell redox homeostasis |
| D | 0098869 | biological_process | cellular oxidant detoxification |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0045454 | biological_process | cell redox homeostasis |
| E | 0098869 | biological_process | cellular oxidant detoxification |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0045454 | biological_process | cell redox homeostasis |
| F | 0098869 | biological_process | cellular oxidant detoxification |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0045454 | biological_process | cell redox homeostasis |
| G | 0098869 | biological_process | cellular oxidant detoxification |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0045454 | biological_process | cell redox homeostasis |
| H | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue FAD A 401 |
| Chain | Residue |
| A | ILE9 |
| A | GLN48 |
| A | PHE50 |
| A | PHE51 |
| A | SER52 |
| A | VAL97 |
| A | ALA124 |
| A | THR125 |
| A | GLY126 |
| A | TYR128 |
| A | VAL292 |
| A | GLY10 |
| A | PHE303 |
| A | ILE304 |
| A | HOH501 |
| A | CYS14 |
| A | ILE32 |
| A | GLU33 |
| A | LYS34 |
| A | GLU39 |
| A | SER40 |
| A | TYR44 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | binding site for residue FAD B 401 |
| Chain | Residue |
| B | ILE9 |
| B | GLY10 |
| B | GLY12 |
| B | PRO13 |
| B | CYS14 |
| B | GLY15 |
| B | GLU33 |
| B | LYS34 |
| B | GLU39 |
| B | SER40 |
| B | TYR44 |
| B | PHE50 |
| B | PHE51 |
| B | SER52 |
| B | VAL97 |
| B | ALA124 |
| B | THR125 |
| B | GLY126 |
| B | TYR128 |
| B | GLY291 |
| B | VAL292 |
| B | PHE303 |
| B | ILE304 |
| site_id | AC3 |
| Number of Residues | 27 |
| Details | binding site for residue FAD C 401 |
| Chain | Residue |
| C | ILE9 |
| C | GLY10 |
| C | GLY12 |
| C | PRO13 |
| C | CYS14 |
| C | GLY15 |
| C | ILE32 |
| C | GLU33 |
| C | LYS34 |
| C | GLU39 |
| C | SER40 |
| C | TYR44 |
| C | PHE50 |
| C | PHE51 |
| C | SER52 |
| C | VAL97 |
| C | ALA124 |
| C | THR125 |
| C | GLY126 |
| C | TYR128 |
| C | GLY291 |
| C | VAL292 |
| C | PHE303 |
| C | ILE304 |
| C | GLU305 |
| C | NAP402 |
| C | HOH502 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue NAP C 402 |
| Chain | Residue |
| C | GLN48 |
| C | THR49 |
| C | TYR128 |
| C | GLY163 |
| C | GLY164 |
| C | LYS165 |
| C | ASN166 |
| C | SER167 |
| C | ASP170 |
| C | TYR186 |
| C | ARG187 |
| C | MET247 |
| C | ILE248 |
| C | GLY249 |
| C | ALA299 |
| C | FAD401 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | binding site for residue FAD D 401 |
| Chain | Residue |
| D | PHE50 |
| D | PHE51 |
| D | SER52 |
| D | VAL97 |
| D | ALA124 |
| D | THR125 |
| D | TYR128 |
| D | GLY291 |
| D | VAL292 |
| D | PHE303 |
| D | ILE304 |
| D | NAP402 |
| D | HOH501 |
| D | HOH502 |
| D | ILE9 |
| D | GLY10 |
| D | GLY12 |
| D | PRO13 |
| D | CYS14 |
| D | ILE32 |
| D | GLU33 |
| D | LYS34 |
| D | GLU39 |
| D | SER40 |
| D | TYR44 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | binding site for residue NAP D 402 |
| Chain | Residue |
| B | ALA299 |
| D | GLN48 |
| D | THR49 |
| D | PHE51 |
| D | TYR127 |
| D | TYR128 |
| D | GLY163 |
| D | GLY164 |
| D | LYS165 |
| D | ASN166 |
| D | SER167 |
| D | ASP170 |
| D | TYR186 |
| D | ARG187 |
| D | SER194 |
| D | MET247 |
| D | ILE248 |
| D | GLY249 |
| D | TYR250 |
| D | ALA299 |
| D | PHE303 |
| D | FAD401 |
| site_id | AC7 |
| Number of Residues | 25 |
| Details | binding site for residue FAD E 401 |
| Chain | Residue |
| E | ILE9 |
| E | GLY10 |
| E | GLY12 |
| E | PRO13 |
| E | CYS14 |
| E | GLY15 |
| E | ILE32 |
| E | GLU33 |
| E | LYS34 |
| E | GLU39 |
| E | SER40 |
| E | TYR44 |
| E | GLN48 |
| E | PHE50 |
| E | PHE51 |
| E | SER52 |
| E | VAL97 |
| E | ALA124 |
| E | THR125 |
| E | GLY126 |
| E | TYR128 |
| E | GLY291 |
| E | VAL292 |
| E | PHE303 |
| E | ILE304 |
| site_id | AC8 |
| Number of Residues | 27 |
| Details | binding site for residue FAD F 401 |
| Chain | Residue |
| F | ILE9 |
| F | GLY10 |
| F | GLY12 |
| F | PRO13 |
| F | CYS14 |
| F | GLY15 |
| F | ILE32 |
| F | GLU33 |
| F | LYS34 |
| F | GLU39 |
| F | SER40 |
| F | TYR44 |
| F | GLN48 |
| F | PHE50 |
| F | PHE51 |
| F | SER52 |
| F | VAL97 |
| F | ALA124 |
| F | THR125 |
| F | GLY126 |
| F | TYR128 |
| F | GLY291 |
| F | VAL292 |
| F | PHE303 |
| F | ILE304 |
| F | NAP402 |
| F | HOH502 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue NAP F 402 |
| Chain | Residue |
| F | THR49 |
| F | PHE51 |
| F | TYR128 |
| F | THR133 |
| F | GLY163 |
| F | LYS165 |
| F | ASN166 |
| F | SER167 |
| F | ASP170 |
| F | TYR186 |
| F | ARG187 |
| F | MET247 |
| F | ILE248 |
| F | GLY249 |
| F | ALA299 |
| F | ASN300 |
| F | FAD401 |
| site_id | AD1 |
| Number of Residues | 23 |
| Details | binding site for residue FAD G 401 |
| Chain | Residue |
| G | GLY12 |
| G | PRO13 |
| G | CYS14 |
| G | GLU33 |
| G | LYS34 |
| G | GLU39 |
| G | SER40 |
| G | TYR44 |
| G | GLN48 |
| G | PHE50 |
| G | PHE51 |
| G | SER52 |
| G | VAL97 |
| G | THR125 |
| G | GLY126 |
| G | TYR128 |
| G | GLN130 |
| G | ASP253 |
| G | PHE256 |
| G | GLY291 |
| G | VAL292 |
| G | PHE303 |
| G | ILE304 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue FAD H 401 |
| Chain | Residue |
| H | ILE9 |
| H | GLY12 |
| H | PRO13 |
| H | CYS14 |
| H | GLU33 |
| H | LYS34 |
| H | SER40 |
| H | TYR44 |
| H | PHE50 |
| H | PHE51 |
| H | SER52 |
| H | VAL97 |
| H | ALA124 |
| H | THR125 |
| H | GLY126 |
| H | VAL292 |
