7A23

Plant mitochondrial respiratory complex I

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0003954	molecular_function	NADH dehydrogenase activity
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
a	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
a	0009536	cellular_component	plastid
a	0015990	biological_process	electron transport coupled proton transport
a	0042773	biological_process	ATP synthesis coupled electron transport
a	0070469	cellular_component	respirasome
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
A	0005886	cellular_component	plasma membrane
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
A	0045271	cellular_component	respiratory chain complex I
A	0046872	molecular_function	metal ion binding
A	0051287	molecular_function	NAD binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0070469	cellular_component	respirasome
A	1902600	biological_process	proton transmembrane transport
b	0005739	cellular_component	mitochondrion
b	0005743	cellular_component	mitochondrial inner membrane
b	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
b	0005758	cellular_component	mitochondrial intermembrane space
b	0009853	biological_process	photorespiration
b	0031966	cellular_component	mitochondrial membrane
b	0045271	cellular_component	respiratory chain complex I
b	0070469	cellular_component	respirasome
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
B	0005829	cellular_component	cytosol
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0070469	cellular_component	respirasome
B	1902600	biological_process	proton transmembrane transport
c	0005739	cellular_component	mitochondrion
c	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
c	0005829	cellular_component	cytosol
c	0009853	biological_process	photorespiration
c	0031966	cellular_component	mitochondrial membrane
c	0045271	cellular_component	respiratory chain complex I
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0009507	cellular_component	chloroplast
C	0009536	cellular_component	plastid
C	0009853	biological_process	photorespiration
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0031966	cellular_component	mitochondrial membrane
C	0042773	biological_process	ATP synthesis coupled electron transport
C	0045271	cellular_component	respiratory chain complex I
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0070469	cellular_component	respirasome
C	1902600	biological_process	proton transmembrane transport
d	0000325	cellular_component	plant-type vacuole
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0005886	cellular_component	plasma membrane
d	0005975	biological_process	carbohydrate metabolic process
d	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
d	0009853	biological_process	photorespiration
d	0031966	cellular_component	mitochondrial membrane
d	0045271	cellular_component	respiratory chain complex I
d	0070469	cellular_component	respirasome
D	0005634	cellular_component	nucleus
D	0005739	cellular_component	mitochondrion
D	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
D	0046872	molecular_function	metal ion binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0070469	cellular_component	respirasome
D	1902600	biological_process	proton transmembrane transport
e	0000036	molecular_function	acyl carrier activity
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005739	cellular_component	mitochondrion
e	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
e	0005759	cellular_component	mitochondrial matrix
e	0005829	cellular_component	cytosol
e	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
e	0006633	biological_process	fatty acid biosynthetic process
e	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
e	0046872	molecular_function	metal ion binding
e	0050897	molecular_function	cobalt ion binding
e	0070469	cellular_component	respirasome
e	1902600	biological_process	proton transmembrane transport
E	0005739	cellular_component	mitochondrion
E	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0009060	biological_process	aerobic respiration
E	0015990	biological_process	electron transport coupled proton transport
E	0016491	molecular_function	oxidoreductase activity
E	0032981	biological_process	mitochondrial respiratory chain complex I assembly
E	0046872	molecular_function	metal ion binding
E	0048038	molecular_function	quinone binding
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0070469	cellular_component	respirasome
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
f	0009853	biological_process	photorespiration
f	0031966	cellular_component	mitochondrial membrane
f	0045271	cellular_component	respiratory chain complex I
f	0070469	cellular_component	respirasome
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
F	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
F	0016491	molecular_function	oxidoreductase activity
F	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
F	0070469	cellular_component	respirasome
F	1902600	biological_process	proton transmembrane transport
g	0005739	cellular_component	mitochondrion
g	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
g	0008150	biological_process	biological_process
G	0005739	cellular_component	mitochondrion
G	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
G	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0016491	molecular_function	oxidoreductase activity
G	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
G	0048038	molecular_function	quinone binding
G	0051287	molecular_function	NAD binding
G	0070469	cellular_component	respirasome
G	1902600	biological_process	proton transmembrane transport
h	0005739	cellular_component	mitochondrion
h	0005743	cellular_component	mitochondrial inner membrane
h	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
h	0070469	cellular_component	respirasome
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0070469	cellular_component	respirasome
H	1902600	biological_process	proton transmembrane transport
i	0000325	cellular_component	plant-type vacuole
i	0005739	cellular_component	mitochondrion
i	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
i	0005829	cellular_component	cytosol
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
I	0009536	cellular_component	plastid
I	0042773	biological_process	ATP synthesis coupled electron transport
I	0070469	cellular_component	respirasome
I	1902600	biological_process	proton transmembrane transport
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
j	0005758	cellular_component	mitochondrial intermembrane space
j	0005829	cellular_component	cytosol
j	0070469	cellular_component	respirasome
J	0005739	cellular_component	mitochondrion
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016020	cellular_component	membrane
J	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
J	0030964	cellular_component	NADH dehydrogenase complex
J	0031966	cellular_component	mitochondrial membrane
J	0070469	cellular_component	respirasome
J	1902600	biological_process	proton transmembrane transport
k	0000036	molecular_function	acyl carrier activity
k	0005515	molecular_function	protein binding
k	0005739	cellular_component	mitochondrion
k	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
k	0005759	cellular_component	mitochondrial matrix
k	0005829	cellular_component	cytosol
k	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
k	0006633	biological_process	fatty acid biosynthetic process
k	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
k	0070469	cellular_component	respirasome
k	1902600	biological_process	proton transmembrane transport
K	0005739	cellular_component	mitochondrion
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0016020	cellular_component	membrane
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0030964	cellular_component	NADH dehydrogenase complex
K	0031966	cellular_component	mitochondrial membrane
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0070469	cellular_component	respirasome
K	1902600	biological_process	proton transmembrane transport
l	0005739	cellular_component	mitochondrion
l	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
l	0009853	biological_process	photorespiration
l	0016020	cellular_component	membrane
l	0031966	cellular_component	mitochondrial membrane
l	0045271	cellular_component	respiratory chain complex I
m	0005739	cellular_component	mitochondrion
m	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
m	0009853	biological_process	photorespiration
m	0031966	cellular_component	mitochondrial membrane
m	0045271	cellular_component	respiratory chain complex I
M	0003954	molecular_function	NADH dehydrogenase activity
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0009536	cellular_component	plastid
M	0015990	biological_process	electron transport coupled proton transport
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0048039	molecular_function	ubiquinone binding
M	0070469	cellular_component	respirasome
n	0000325	cellular_component	plant-type vacuole
n	0005507	molecular_function	copper ion binding
n	0005730	cellular_component	nucleolus
n	0005739	cellular_component	mitochondrion
n	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
n	0005777	cellular_component	peroxisome
n	0009853	biological_process	photorespiration
n	0031966	cellular_component	mitochondrial membrane
n	0045271	cellular_component	respiratory chain complex I
N	0005739	cellular_component	mitochondrion
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0016020	cellular_component	membrane
N	0031966	cellular_component	mitochondrial membrane
N	0070469	cellular_component	respirasome
N	1902600	biological_process	proton transmembrane transport
o	0005515	molecular_function	protein binding
o	0005739	cellular_component	mitochondrion
o	0016020	cellular_component	membrane
o	0031966	cellular_component	mitochondrial membrane
o	0046872	molecular_function	metal ion binding
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
O	0006970	biological_process	response to osmotic stress
O	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
O	0009536	cellular_component	plastid
O	0009631	biological_process	cold acclimation
O	0022900	biological_process	electron transport chain
O	0050897	molecular_function	cobalt ion binding
O	0070469	cellular_component	respirasome
O	1902600	biological_process	proton transmembrane transport
p	0004089	molecular_function	carbonate dehydratase activity
p	0005634	cellular_component	nucleus
p	0005739	cellular_component	mitochondrion
p	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
p	0009853	biological_process	photorespiration
p	0016020	cellular_component	membrane
p	0016829	molecular_function	lyase activity
p	0031966	cellular_component	mitochondrial membrane
p	0045271	cellular_component	respiratory chain complex I
p	0046872	molecular_function	metal ion binding
p	0070207	biological_process	protein homotrimerization
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
P	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P	0070469	cellular_component	respirasome
q	0004089	molecular_function	carbonate dehydratase activity
q	0005634	cellular_component	nucleus
q	0005739	cellular_component	mitochondrion
q	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
q	0009853	biological_process	photorespiration
q	0016020	cellular_component	membrane
q	0016829	molecular_function	lyase activity
q	0031966	cellular_component	mitochondrial membrane
q	0045271	cellular_component	respiratory chain complex I
q	0046872	molecular_function	metal ion binding
q	0070207	biological_process	protein homotrimerization
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Q	0009536	cellular_component	plastid
Q	0070469	cellular_component	respirasome
R	0005515	molecular_function	protein binding
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
R	0009536	cellular_component	plastid
R	0009853	biological_process	photorespiration
R	0022904	biological_process	respiratory electron transport chain
R	0031966	cellular_component	mitochondrial membrane
R	0045271	cellular_component	respiratory chain complex I
R	0070469	cellular_component	respirasome
S	0005739	cellular_component	mitochondrion
S	0005886	cellular_component	plasma membrane
t	0005576	cellular_component	extracellular region
t	0005739	cellular_component	mitochondrion
t	0005743	cellular_component	mitochondrial inner membrane
t	0009853	biological_process	photorespiration
t	0022900	biological_process	electron transport chain
t	0031966	cellular_component	mitochondrial membrane
t	0045271	cellular_component	respiratory chain complex I
t	0070469	cellular_component	respirasome
T	0005739	cellular_component	mitochondrion
T	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
T	0005759	cellular_component	mitochondrial matrix
T	0070469	cellular_component	respirasome
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
U	0005829	cellular_component	cytosol
U	0016020	cellular_component	membrane
U	0032981	biological_process	mitochondrial respiratory chain complex I assembly
U	0050897	molecular_function	cobalt ion binding
U	0070469	cellular_component	respirasome
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
V	0070469	cellular_component	respirasome
W	0005739	cellular_component	mitochondrion
W	0005829	cellular_component	cytosol
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
X	0005829	cellular_component	cytosol
X	0070469	cellular_component	respirasome
Y	0005739	cellular_component	mitochondrion
Y	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Y	0005758	cellular_component	mitochondrial intermembrane space
Y	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
Y	0009536	cellular_component	plastid
Y	0070469	cellular_component	respirasome
Z	0005576	cellular_component	extracellular region
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Z	0009793	biological_process	embryo development ending in seed dormancy
Z	0009853	biological_process	photorespiration
Z	0031966	cellular_component	mitochondrial membrane
Z	0045271	cellular_component	respiratory chain complex I
Z	0070469	cellular_component	respirasome

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDSVEVVMAL

Chain	Residue	Details
e	ASP78-LEU93
k	ASP74-ILE89

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
D	CYS123-PRO134
D	CYS162-PRO173

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
G	LEU47-LYS58

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvwDMFgvsfinHpdlRrIL

Chain	Residue	Details
F	GLU112-LEU133

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYhsrlsiaGnCRmC

Chain	Residue	Details
C	PRO103-CYS120

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
C	CYS170-GLN182

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCVrF

Chain	Residue	Details
C	ARG217-PHE227

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALLES

Chain	Residue	Details
A	GLY223-SER238

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
A	GLU400-GLY411

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpLaDGLKLIlKE

Chain	Residue	Details
H	GLY47-GLU62

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLPEAEaeLVa.G

Chain	Residue	Details
H	PRO202-GLY215

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DglFSvgemeCMGcCvnAP

Chain	Residue	Details
B	ASP161-PRO179

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
E	GLY174-PRO190

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
q	ARG86
p	HIS130
p	HIS135
p	ASN209
a	ILE461-ALA481
a	GLY619-PHE639
q	GLN101
q	HIS107
q	HIS130
q	HIS135
q	ASN209
p	ARG86
p	GLN101
p	HIS107

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01184

Chain	Residue	Details
C	HIS166
C	CYS170
C	CYS173
C	CYS179

---