7A06
Structure of human CKa1 in complex with compound o
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue QTH A 501 |
| Chain | Residue |
| A | TYR256 |
| A | ASP306 |
| A | TYR333 |
| A | TRP420 |
| A | TRP423 |
| A | TYR437 |
| A | QTH502 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue QTH A 502 |
| Chain | Residue |
| A | TRP420 |
| A | TRP423 |
| A | PHE435 |
| A | TYR440 |
| A | QTH501 |
| A | HOH647 |
| A | GLN308 |
| A | TYR354 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | TYR352 |
| A | ALA443 |
| A | ALA447 |
| A | HOH610 |
| A | HOH691 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | HIS112 |
| A | ILE113 |
| A | SER114 |
| A | GLN126 |
| A | CYS127 |
| A | SER128 |
| A | HOH720 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ARG90 |
| A | MET123 |
| A | HOH693 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | PHE98 |
| A | LEU179 |
| A | ILE199 |
| A | PHE200 |
| A | PHE242 |
| A | ASN243 |
| A | HOH654 |
| A | HOH844 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | TYR256 |
| A | GLU259 |
| A | TRP423 |
| A | VAL426 |
| A | GLN427 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | ARG270 |
| A | TYR359 |
| A | GLY436 |
| A | TYR437 |
| A | MET438 |
| A | ASP439 |
| A | HOH847 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | MET351 |
| A | HIS417 |
| A | HIS450 |
| A | GLN451 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | HIS112 |
| A | PRO130 |
| A | ASP131 |
| A | THR132 |
| A | HOH742 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | ARG141 |
| A | SER394 |
| A | GLU396 |
| A | GLU397 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | LYS258 |
| A | LEU261 |
| A | ARG262 |
| A | GLU403 |
| A | GLU404 |
| A | HOH608 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | GLU245 |
| A | PRO246 |
| A | LYS247 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 514 |
| Chain | Residue |
| A | ARG290 |
| A | LEU293 |
| A | GLU294 |
| A | TYR338 |
| A | HOH648 |
| A | HOH906 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 515 |
| Chain | Residue |
| A | ARG270 |
| A | ALA428 |
| A | SER431 |
| A | ILE433 |
| A | HOH659 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17007874","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20299452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3G15","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17007874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CKQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"34077757","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"34077757","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
