6ZXV
Structure of Archaeoglobus fulgidus Trm11 m2G10 tRNA methyltransferase enzyme bound to sinefungin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008173 | molecular_function | RNA methyltransferase activity |
| A | 0016423 | molecular_function | tRNA (guanine) methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0160101 | molecular_function | tRNA (guanine(10)-N2)-dimethyltransferase activity |
| A | 0160102 | molecular_function | tRNA (guanine(10)-N2)-methyltransferase activity |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008173 | molecular_function | RNA methyltransferase activity |
| B | 0016423 | molecular_function | tRNA (guanine) methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030488 | biological_process | tRNA methylation |
| B | 0032259 | biological_process | methylation |
| B | 0160101 | molecular_function | tRNA (guanine(10)-N2)-dimethyltransferase activity |
| B | 0160102 | molecular_function | tRNA (guanine(10)-N2)-methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue SFG A 401 |
| Chain | Residue |
| A | MET156 |
| A | ASP231 |
| A | ALA232 |
| A | ASP248 |
| A | TYR249 |
| A | PRO250 |
| A | TYR251 |
| A | ARG253 |
| A | LEU264 |
| A | HOH506 |
| A | HOH557 |
| A | PRO183 |
| A | HOH558 |
| A | MET184 |
| A | GLY186 |
| A | ASP205 |
| A | PHE206 |
| A | ILE207 |
| A | ILE210 |
| A | GLY230 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | GLU50 |
| A | ARG166 |
| A | LEU196 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | SER8 |
| A | ALA9 |
| A | ARG37 |
| A | ASN56 |
| A | LYS163 |
| A | HOH531 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | GLU208 |
| A | VAL211 |
| A | ARG212 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | binding site for residue SFG B 401 |
| Chain | Residue |
| B | PRO183 |
| B | MET184 |
| B | GLY186 |
| B | ASP205 |
| B | PHE206 |
| B | ILE207 |
| B | ILE210 |
| B | GLY230 |
| B | ASP231 |
| B | ALA232 |
| B | ASP248 |
| B | TYR249 |
| B | PRO250 |
| B | TYR251 |
| B | ARG253 |
| B | LEU264 |
| B | HOH527 |
| B | HOH540 |
| B | HOH551 |
| B | HOH581 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | ARG147 |
| B | SER292 |
| B | PHE293 |
Functional Information from PROSITE/UniProt
| site_id | PS01261 |
| Number of Residues | 12 |
| Details | UPF0020 Uncharacterized protein family UPF0020 signature. DPMCGTGsflIE |
| Chain | Residue | Details |
| A | ASP182-GLU193 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 180 |
| Details | Domain: {"description":"THUMP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00529","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
