Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6ZTZ

Assembly intermediates of orthoreovirus captured in the cell

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003724	molecular_function	RNA helicase activity
B	0016787	molecular_function	hydrolase activity
C	0003724	molecular_function	RNA helicase activity
C	0016787	molecular_function	hydrolase activity
D	0019028	cellular_component	viral capsid
D	0039625	cellular_component	viral inner capsid
D	0044423	cellular_component	virion component
K	0019028	cellular_component	viral capsid
K	0020002	cellular_component	host cell plasma membrane
K	0033650	cellular_component	host cell mitochondrion
K	0039624	cellular_component	viral outer capsid
K	0044165	cellular_component	host cell endoplasmic reticulum
K	0044423	cellular_component	virion component
K	0046718	biological_process	symbiont entry into host cell
K	0046812	molecular_function	host cell surface binding
K	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane
L	0019028	cellular_component	viral capsid
L	0020002	cellular_component	host cell plasma membrane
L	0033650	cellular_component	host cell mitochondrion
L	0039624	cellular_component	viral outer capsid
L	0044165	cellular_component	host cell endoplasmic reticulum
L	0044423	cellular_component	virion component
L	0046718	biological_process	symbiont entry into host cell
L	0046812	molecular_function	host cell surface binding
L	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane
M	0019028	cellular_component	viral capsid
M	0020002	cellular_component	host cell plasma membrane
M	0033650	cellular_component	host cell mitochondrion
M	0039624	cellular_component	viral outer capsid
M	0044165	cellular_component	host cell endoplasmic reticulum
M	0044423	cellular_component	virion component
M	0046718	biological_process	symbiont entry into host cell
M	0046812	molecular_function	host cell surface binding
M	0140267	biological_process	symbiont entry into host cell via permeabilization of host membrane
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
O	0004484	molecular_function	mRNA guanylyltransferase activity
O	0005524	molecular_function	ATP binding
O	0005525	molecular_function	GTP binding
O	0006370	biological_process	7-methylguanosine mRNA capping
O	0006397	biological_process	mRNA processing
O	0008168	molecular_function	methyltransferase activity
O	0016740	molecular_function	transferase activity
O	0016779	molecular_function	nucleotidyltransferase activity
O	0019028	cellular_component	viral capsid
O	0019030	cellular_component	icosahedral viral capsid
O	0032259	biological_process	methylation
O	0039624	cellular_component	viral outer capsid
O	0044423	cellular_component	virion component
O	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation
P	0019028	cellular_component	viral capsid
P	0039625	cellular_component	viral inner capsid
P	0044423	cellular_component	virion component
X	0003723	molecular_function	RNA binding
X	0005198	molecular_function	structural molecule activity
X	0006351	biological_process	DNA-templated transcription
X	0008270	molecular_function	zinc ion binding
X	0019028	cellular_component	viral capsid
X	0019058	biological_process	viral life cycle
X	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
X	0030430	cellular_component	host cell cytoplasm
X	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
X	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
X	0039624	cellular_component	viral outer capsid
X	0042025	cellular_component	host cell nucleus
X	0044423	cellular_component	virion component
X	0046872	molecular_function	metal ion binding
X	0052031	biological_process	symbiont-mediated perturbation of host defense response
X	0052170	biological_process	symbiont-mediated suppression of host innate immune response
Y	0003723	molecular_function	RNA binding
Y	0005198	molecular_function	structural molecule activity
Y	0006351	biological_process	DNA-templated transcription
Y	0008270	molecular_function	zinc ion binding
Y	0019028	cellular_component	viral capsid
Y	0019058	biological_process	viral life cycle
Y	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
Y	0030430	cellular_component	host cell cytoplasm
Y	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
Y	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
Y	0039624	cellular_component	viral outer capsid
Y	0042025	cellular_component	host cell nucleus
Y	0044423	cellular_component	virion component
Y	0046872	molecular_function	metal ion binding
Y	0052031	biological_process	symbiont-mediated perturbation of host defense response
Y	0052170	biological_process	symbiont-mediated suppression of host innate immune response
Z	0003723	molecular_function	RNA binding
Z	0005198	molecular_function	structural molecule activity
Z	0006351	biological_process	DNA-templated transcription
Z	0008270	molecular_function	zinc ion binding
Z	0019028	cellular_component	viral capsid
Z	0019058	biological_process	viral life cycle
Z	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
Z	0030430	cellular_component	host cell cytoplasm
Z	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
Z	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
Z	0039624	cellular_component	viral outer capsid
Z	0042025	cellular_component	host cell nucleus
Z	0044423	cellular_component	virion component
Z	0046872	molecular_function	metal ion binding
Z	0052031	biological_process	symbiont-mediated perturbation of host defense response
Z	0052170	biological_process	symbiont-mediated suppression of host innate immune response

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cmh..ClgvVgslqrklkHlph..H

Chain	Residue	Details
X	CYS51-HIS71

site_id	PS00430
Number of Residues	90
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. aglctsfkivpivpaqvpqdvlaytfftssyaiqspfpeaavsrivvhtrwasnvdfdrdssvimapptennihlfkqllnt.................................ETLSVRGA

Chain	Residue	Details
C	ALA260-ALA349
B	ASN241-ALA349

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Site: {"description":"Cleavage","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	18
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Involved in formation of the phosphoamide bond"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	66
Details	Zinc finger: {"description":"CCHC-type","evidences":[{"source":"UniProtKB","id":"P03527","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)