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6ZTZ

Assembly intermediates of orthoreovirus captured in the cell

Functional Information from GO Data
ChainGOidnamespacecontents
B0003724molecular_functionRNA helicase activity
B0016787molecular_functionhydrolase activity
C0003724molecular_functionRNA helicase activity
C0016787molecular_functionhydrolase activity
D0019028cellular_componentviral capsid
D0039625cellular_componentviral inner capsid
K0006915biological_processapoptotic process
K0016020cellular_componentmembrane
K0019028cellular_componentviral capsid
K0020002cellular_componenthost cell plasma membrane
K0033650cellular_componenthost cell mitochondrion
K0039624cellular_componentviral outer capsid
K0044165cellular_componenthost cell endoplasmic reticulum
K0046718biological_processsymbiont entry into host cell
K0046812molecular_functionhost cell surface binding
K0140267biological_processsymbiont entry into host cell via permeabilization of host membrane
L0006915biological_processapoptotic process
L0016020cellular_componentmembrane
L0019028cellular_componentviral capsid
L0020002cellular_componenthost cell plasma membrane
L0033650cellular_componenthost cell mitochondrion
L0039624cellular_componentviral outer capsid
L0044165cellular_componenthost cell endoplasmic reticulum
L0046718biological_processsymbiont entry into host cell
L0046812molecular_functionhost cell surface binding
L0140267biological_processsymbiont entry into host cell via permeabilization of host membrane
M0006915biological_processapoptotic process
M0016020cellular_componentmembrane
M0019028cellular_componentviral capsid
M0020002cellular_componenthost cell plasma membrane
M0033650cellular_componenthost cell mitochondrion
M0039624cellular_componentviral outer capsid
M0044165cellular_componenthost cell endoplasmic reticulum
M0046718biological_processsymbiont entry into host cell
M0046812molecular_functionhost cell surface binding
M0140267biological_processsymbiont entry into host cell via permeabilization of host membrane
O0004482molecular_functionmRNA 5'-cap (guanine-N7-)-methyltransferase activity
O0004484molecular_functionmRNA guanylyltransferase activity
O0005524molecular_functionATP binding
O0005525molecular_functionGTP binding
O0006370biological_process7-methylguanosine mRNA capping
O0008168molecular_functionmethyltransferase activity
O0016779molecular_functionnucleotidyltransferase activity
O0019028cellular_componentviral capsid
O0019030cellular_componenticosahedral viral capsid
O0032259biological_processmethylation
O0039624cellular_componentviral outer capsid
O0106005biological_processRNA 5'-cap (guanine-N7)-methylation
P0019028cellular_componentviral capsid
P0039625cellular_componentviral inner capsid
X0003723molecular_functionRNA binding
X0005198molecular_functionstructural molecule activity
X0006417biological_processregulation of translation
X0019028cellular_componentviral capsid
X0019049biological_processvirus-mediated perturbation of host defense response
X0019058biological_processviral life cycle
X0030291molecular_functionprotein serine/threonine kinase inhibitor activity
X0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
X0039580biological_processsymbiont-mediated suppression of host PKR/eIFalpha signaling
X0039624cellular_componentviral outer capsid
X0046872molecular_functionmetal ion binding
X0052170biological_processsymbiont-mediated suppression of host innate immune response
Y0003723molecular_functionRNA binding
Y0005198molecular_functionstructural molecule activity
Y0006417biological_processregulation of translation
Y0019028cellular_componentviral capsid
Y0019049biological_processvirus-mediated perturbation of host defense response
Y0019058biological_processviral life cycle
Y0030291molecular_functionprotein serine/threonine kinase inhibitor activity
Y0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
Y0039580biological_processsymbiont-mediated suppression of host PKR/eIFalpha signaling
Y0039624cellular_componentviral outer capsid
Y0046872molecular_functionmetal ion binding
Y0052170biological_processsymbiont-mediated suppression of host innate immune response
Z0003723molecular_functionRNA binding
Z0005198molecular_functionstructural molecule activity
Z0006417biological_processregulation of translation
Z0019028cellular_componentviral capsid
Z0019049biological_processvirus-mediated perturbation of host defense response
Z0019058biological_processviral life cycle
Z0030291molecular_functionprotein serine/threonine kinase inhibitor activity
Z0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
Z0039580biological_processsymbiont-mediated suppression of host PKR/eIFalpha signaling
Z0039624cellular_componentviral outer capsid
Z0046872molecular_functionmetal ion binding
Z0052170biological_processsymbiont-mediated suppression of host innate immune response
Functional Information from PROSITE/UniProt
site_idPS00028
Number of Residues21
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cmh..ClgvVgslqrklkHlph..H
ChainResidueDetails
XCYS51-HIS71

site_idPS00430
Number of Residues90
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. aglctsfkivpivpaqvpqdvlaytfftssyaiqspfpeaavsrivvhtrwasnvdfdrdssvimapptennihlfkqllnt.................................ETLSVRGA
ChainResidueDetails
CALA260-ALA349
BASN241-ALA349

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues66
DetailsZN_FING: CCHC-type => ECO:0000250|UniProtKB:P03527
ChainResidueDetails
XCYS51-CYS73
YCYS51-CYS73
ZCYS51-CYS73

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Involved in formation of the phosphoamide bond
ChainResidueDetails
OLYS190
LPRO135
LMET483
LGLY507
LASP553
MASN12
MHIS106
MPRO135
MMET483
MGLY507
KHIS106
MASP553
KPRO135
KMET483
KGLY507
KASP553
LASN12
LHIS106

223532

PDB entries from 2024-08-07

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