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6ZTY

Assembly intermediates of orthoreovirus captured in the cell

Functional Information from GO Data
ChainGOidnamespacecontents
H0019028cellular_componentviral capsid
H0020002cellular_componenthost cell plasma membrane
H0033650cellular_componenthost cell mitochondrion
H0039624cellular_componentviral outer capsid
H0044165cellular_componenthost cell endoplasmic reticulum
H0044423cellular_componentvirion component
H0046718biological_processsymbiont entry into host cell
H0046812molecular_functionhost cell surface binding
H0140267biological_processsymbiont entry into host cell via permeabilization of host membrane
I0019028cellular_componentviral capsid
I0020002cellular_componenthost cell plasma membrane
I0033650cellular_componenthost cell mitochondrion
I0039624cellular_componentviral outer capsid
I0044165cellular_componenthost cell endoplasmic reticulum
I0044423cellular_componentvirion component
I0046718biological_processsymbiont entry into host cell
I0046812molecular_functionhost cell surface binding
I0140267biological_processsymbiont entry into host cell via permeabilization of host membrane
J0019028cellular_componentviral capsid
J0020002cellular_componenthost cell plasma membrane
J0033650cellular_componenthost cell mitochondrion
J0039624cellular_componentviral outer capsid
J0044165cellular_componenthost cell endoplasmic reticulum
J0044423cellular_componentvirion component
J0046718biological_processsymbiont entry into host cell
J0046812molecular_functionhost cell surface binding
J0140267biological_processsymbiont entry into host cell via permeabilization of host membrane
U0003723molecular_functionRNA binding
U0005198molecular_functionstructural molecule activity
U0006351biological_processDNA-templated transcription
U0008270molecular_functionzinc ion binding
U0019028cellular_componentviral capsid
U0019058biological_processviral life cycle
U0030291molecular_functionprotein serine/threonine kinase inhibitor activity
U0030430cellular_componenthost cell cytoplasm
U0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
U0039580biological_processsymbiont-mediated suppression of host PKR/eIFalpha signaling
U0039624cellular_componentviral outer capsid
U0042025cellular_componenthost cell nucleus
U0044423cellular_componentvirion component
U0046872molecular_functionmetal ion binding
U0052031biological_processsymbiont-mediated perturbation of host defense response
U0052170biological_processsymbiont-mediated suppression of host innate immune response
V0003723molecular_functionRNA binding
V0005198molecular_functionstructural molecule activity
V0006351biological_processDNA-templated transcription
V0008270molecular_functionzinc ion binding
V0019028cellular_componentviral capsid
V0019058biological_processviral life cycle
V0030291molecular_functionprotein serine/threonine kinase inhibitor activity
V0030430cellular_componenthost cell cytoplasm
V0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
V0039580biological_processsymbiont-mediated suppression of host PKR/eIFalpha signaling
V0039624cellular_componentviral outer capsid
V0042025cellular_componenthost cell nucleus
V0044423cellular_componentvirion component
V0046872molecular_functionmetal ion binding
V0052031biological_processsymbiont-mediated perturbation of host defense response
V0052170biological_processsymbiont-mediated suppression of host innate immune response
W0003723molecular_functionRNA binding
W0005198molecular_functionstructural molecule activity
W0006351biological_processDNA-templated transcription
W0008270molecular_functionzinc ion binding
W0019028cellular_componentviral capsid
W0019058biological_processviral life cycle
W0030291molecular_functionprotein serine/threonine kinase inhibitor activity
W0030430cellular_componenthost cell cytoplasm
W0039502biological_processsymbiont-mediated suppression of host type I interferon-mediated signaling pathway
W0039580biological_processsymbiont-mediated suppression of host PKR/eIFalpha signaling
W0039624cellular_componentviral outer capsid
W0042025cellular_componenthost cell nucleus
W0044423cellular_componentvirion component
W0046872molecular_functionmetal ion binding
W0052031biological_processsymbiont-mediated perturbation of host defense response
W0052170biological_processsymbiont-mediated suppression of host innate immune response
Functional Information from PROSITE/UniProt
site_idPS00028
Number of Residues21
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cmh..ClgvVgslqrklkHlph..H
ChainResidueDetails
UCYS51-HIS71

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsSite: {"description":"Cleavage","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues18
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues66
DetailsZinc finger: {"description":"CCHC-type","evidences":[{"source":"UniProtKB","id":"P03527","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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