6ZQG

Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-C

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
CJ	0005515	molecular_function	protein binding
CJ	0005654	cellular_component	nucleoplasm
CJ	0005730	cellular_component	nucleolus
CJ	0006364	biological_process	rRNA processing
CJ	0019843	molecular_function	rRNA binding
CJ	0030490	biological_process	maturation of SSU-rRNA
CJ	0030515	molecular_function	snoRNA binding
CJ	0030686	cellular_component	90S preribosome
CJ	0032040	cellular_component	small-subunit processome
CJ	0034337	biological_process	RNA folding
CJ	0034457	cellular_component	Mpp10 complex
CJ	0042134	molecular_function	rRNA primary transcript binding
CJ	0042254	biological_process	ribosome biogenesis
CJ	0042274	biological_process	ribosomal small subunit biogenesis
CJ	0043047	molecular_function	single-stranded telomeric DNA binding
CJ	0140691	molecular_function	RNA folding chaperone
CJ	1990904	cellular_component	ribonucleoprotein complex
CK	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CK	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CK	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CK	0003674	molecular_function	molecular_function
CK	0005515	molecular_function	protein binding
CK	0005634	cellular_component	nucleus
CK	0005654	cellular_component	nucleoplasm
CK	0005730	cellular_component	nucleolus
CK	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
CK	0006364	biological_process	rRNA processing
CK	0030490	biological_process	maturation of SSU-rRNA
CK	0030686	cellular_component	90S preribosome
CK	0032040	cellular_component	small-subunit processome
CK	0034457	cellular_component	Mpp10 complex
CK	0042254	biological_process	ribosome biogenesis
CK	0042802	molecular_function	identical protein binding
CK	1990904	cellular_component	ribonucleoprotein complex
CL	0000166	molecular_function	nucleotide binding
CL	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CL	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CL	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CL	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CL	0003723	molecular_function	RNA binding
CL	0003729	molecular_function	mRNA binding
CL	0003924	molecular_function	GTPase activity
CL	0005515	molecular_function	protein binding
CL	0005524	molecular_function	ATP binding
CL	0005525	molecular_function	GTP binding
CL	0005634	cellular_component	nucleus
CL	0005654	cellular_component	nucleoplasm
CL	0005730	cellular_component	nucleolus
CL	0005737	cellular_component	cytoplasm
CL	0005739	cellular_component	mitochondrion
CL	0016787	molecular_function	hydrolase activity
CL	0016887	molecular_function	ATP hydrolysis activity
CL	0030490	biological_process	maturation of SSU-rRNA
CL	0030686	cellular_component	90S preribosome
CL	0032040	cellular_component	small-subunit processome
CL	0034511	molecular_function	U3 snoRNA binding
CL	0042254	biological_process	ribosome biogenesis
CL	0042274	biological_process	ribosomal small subunit biogenesis
CL	2000232	biological_process	regulation of rRNA processing
CM	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CM	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CM	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CM	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CM	0003824	molecular_function	catalytic activity
CM	0003963	molecular_function	RNA-3'-phosphate cyclase activity
CM	0004521	molecular_function	RNA endonuclease activity
CM	0005515	molecular_function	protein binding
CM	0005654	cellular_component	nucleoplasm
CM	0005730	cellular_component	nucleolus
CM	0006364	biological_process	rRNA processing
CM	0006396	biological_process	RNA processing
CM	0008047	molecular_function	enzyme activator activity
CM	0030490	biological_process	maturation of SSU-rRNA
CM	0030686	cellular_component	90S preribosome
CM	0042254	biological_process	ribosome biogenesis
CM	0042274	biological_process	ribosomal small subunit biogenesis
CM	2000232	biological_process	regulation of rRNA processing
DA	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DA	0002181	biological_process	cytoplasmic translation
DA	0003735	molecular_function	structural constituent of ribosome
DA	0005737	cellular_component	cytoplasm
DA	0005829	cellular_component	cytosol
DA	0005840	cellular_component	ribosome
DA	0006412	biological_process	translation
DA	0022627	cellular_component	cytosolic small ribosomal subunit
DA	0030686	cellular_component	90S preribosome
DA	1990904	cellular_component	ribonucleoprotein complex
Db	0000028	biological_process	ribosomal small subunit assembly
Db	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Db	0003723	molecular_function	RNA binding
Db	0003735	molecular_function	structural constituent of ribosome
Db	0005737	cellular_component	cytoplasm
Db	0005829	cellular_component	cytosol
Db	0005840	cellular_component	ribosome
Db	0006412	biological_process	translation
Db	0008270	molecular_function	zinc ion binding
Db	0022627	cellular_component	cytosolic small ribosomal subunit
Db	0046872	molecular_function	metal ion binding
Db	1990904	cellular_component	ribonucleoprotein complex
Dc	0000028	biological_process	ribosomal small subunit assembly
Dc	0000054	biological_process	ribosomal subunit export from nucleus
Dc	0003735	molecular_function	structural constituent of ribosome
Dc	0005515	molecular_function	protein binding
Dc	0005737	cellular_component	cytoplasm
Dc	0005829	cellular_component	cytosol
Dc	0005840	cellular_component	ribosome
Dc	0006412	biological_process	translation
Dc	0022627	cellular_component	cytosolic small ribosomal subunit
Dc	0030490	biological_process	maturation of SSU-rRNA
Dc	1900153	biological_process	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Dc	1990904	cellular_component	ribonucleoprotein complex
DE	0002181	biological_process	cytoplasmic translation
DE	0003723	molecular_function	RNA binding
DE	0003735	molecular_function	structural constituent of ribosome
DE	0005737	cellular_component	cytoplasm
DE	0005829	cellular_component	cytosol
DE	0005840	cellular_component	ribosome
DE	0006412	biological_process	translation
DE	0019843	molecular_function	rRNA binding
DE	0022627	cellular_component	cytosolic small ribosomal subunit
DE	0030686	cellular_component	90S preribosome
DE	1990904	cellular_component	ribonucleoprotein complex
DF	0000054	biological_process	ribosomal subunit export from nucleus
DF	0002181	biological_process	cytoplasmic translation
DF	0003723	molecular_function	RNA binding
DF	0003729	molecular_function	mRNA binding
DF	0003735	molecular_function	structural constituent of ribosome
DF	0005515	molecular_function	protein binding
DF	0005737	cellular_component	cytoplasm
DF	0005829	cellular_component	cytosol
DF	0005840	cellular_component	ribosome
DF	0006412	biological_process	translation
DF	0006450	biological_process	regulation of translational fidelity
DF	0015935	cellular_component	small ribosomal subunit
DF	0019843	molecular_function	rRNA binding
DF	0022627	cellular_component	cytosolic small ribosomal subunit
DF	0030490	biological_process	maturation of SSU-rRNA
DF	0030686	cellular_component	90S preribosome
DF	1990904	cellular_component	ribonucleoprotein complex
DG	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DG	0003735	molecular_function	structural constituent of ribosome
DG	0005654	cellular_component	nucleoplasm
DG	0005730	cellular_component	nucleolus
DG	0005737	cellular_component	cytoplasm
DG	0005829	cellular_component	cytosol
DG	0005840	cellular_component	ribosome
DG	0006364	biological_process	rRNA processing
DG	0006412	biological_process	translation
DG	0022627	cellular_component	cytosolic small ribosomal subunit
DG	0030686	cellular_component	90S preribosome
DG	0032040	cellular_component	small-subunit processome
DG	0042254	biological_process	ribosome biogenesis
DG	1990904	cellular_component	ribonucleoprotein complex
DH	0002181	biological_process	cytoplasmic translation
DH	0003735	molecular_function	structural constituent of ribosome
DH	0005654	cellular_component	nucleoplasm
DH	0005730	cellular_component	nucleolus
DH	0005737	cellular_component	cytoplasm
DH	0005829	cellular_component	cytosol
DH	0005840	cellular_component	ribosome
DH	0006364	biological_process	rRNA processing
DH	0006412	biological_process	translation
DH	0022627	cellular_component	cytosolic small ribosomal subunit
DH	0030686	cellular_component	90S preribosome
DH	0032040	cellular_component	small-subunit processome
DH	0042254	biological_process	ribosome biogenesis
DH	0042274	biological_process	ribosomal small subunit biogenesis
DH	1990904	cellular_component	ribonucleoprotein complex
DI	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DI	0003735	molecular_function	structural constituent of ribosome
DI	0005737	cellular_component	cytoplasm
DI	0005829	cellular_component	cytosol
DI	0005840	cellular_component	ribosome
DI	0006412	biological_process	translation
DI	0022627	cellular_component	cytosolic small ribosomal subunit
DI	0030686	cellular_component	90S preribosome
DI	1990904	cellular_component	ribonucleoprotein complex
DJ	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DJ	0003723	molecular_function	RNA binding
DJ	0003735	molecular_function	structural constituent of ribosome
DJ	0005515	molecular_function	protein binding
DJ	0005654	cellular_component	nucleoplasm
DJ	0005730	cellular_component	nucleolus
DJ	0005737	cellular_component	cytoplasm
DJ	0005829	cellular_component	cytosol
DJ	0005840	cellular_component	ribosome
DJ	0006364	biological_process	rRNA processing
DJ	0006412	biological_process	translation
DJ	0015935	cellular_component	small ribosomal subunit
DJ	0019843	molecular_function	rRNA binding
DJ	0022627	cellular_component	cytosolic small ribosomal subunit
DJ	0030476	biological_process	ascospore wall assembly
DJ	0030686	cellular_component	90S preribosome
DJ	0032040	cellular_component	small-subunit processome
DJ	0042254	biological_process	ribosome biogenesis
DJ	0042274	biological_process	ribosomal small subunit biogenesis
DJ	1990904	cellular_component	ribonucleoprotein complex
DL	0000028	biological_process	ribosomal small subunit assembly
DL	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DL	0003723	molecular_function	RNA binding
DL	0003735	molecular_function	structural constituent of ribosome
DL	0005737	cellular_component	cytoplasm
DL	0005829	cellular_component	cytosol
DL	0005840	cellular_component	ribosome
DL	0006412	biological_process	translation
DL	0019843	molecular_function	rRNA binding
DL	0022627	cellular_component	cytosolic small ribosomal subunit
DL	0030686	cellular_component	90S preribosome
DL	1990904	cellular_component	ribonucleoprotein complex
DN	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DN	0002181	biological_process	cytoplasmic translation
DN	0003735	molecular_function	structural constituent of ribosome
DN	0005730	cellular_component	nucleolus
DN	0005737	cellular_component	cytoplasm
DN	0005829	cellular_component	cytosol
DN	0005840	cellular_component	ribosome
DN	0006412	biological_process	translation
DN	0022627	cellular_component	cytosolic small ribosomal subunit
DN	0030686	cellular_component	90S preribosome
DN	0070181	molecular_function	small ribosomal subunit rRNA binding
DN	1990904	cellular_component	ribonucleoprotein complex
DO	0000028	biological_process	ribosomal small subunit assembly
DO	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DO	0002181	biological_process	cytoplasmic translation
DO	0003729	molecular_function	mRNA binding
DO	0003735	molecular_function	structural constituent of ribosome
DO	0005654	cellular_component	nucleoplasm
DO	0005730	cellular_component	nucleolus
DO	0005737	cellular_component	cytoplasm
DO	0005829	cellular_component	cytosol
DO	0005840	cellular_component	ribosome
DO	0006364	biological_process	rRNA processing
DO	0006412	biological_process	translation
DO	0022627	cellular_component	cytosolic small ribosomal subunit
DO	0030686	cellular_component	90S preribosome
DO	0032040	cellular_component	small-subunit processome
DO	0042254	biological_process	ribosome biogenesis
DO	1990904	cellular_component	ribonucleoprotein complex
DQ	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DQ	0003723	molecular_function	RNA binding
DQ	0003735	molecular_function	structural constituent of ribosome
DQ	0005737	cellular_component	cytoplasm
DQ	0005829	cellular_component	cytosol
DQ	0005840	cellular_component	ribosome
DQ	0006412	biological_process	translation
DQ	0006413	biological_process	translational initiation
DQ	0022627	cellular_component	cytosolic small ribosomal subunit
DQ	0030686	cellular_component	90S preribosome
DQ	1990904	cellular_component	ribonucleoprotein complex
DS	0003676	molecular_function	nucleic acid binding
DS	0003723	molecular_function	RNA binding
DS	0003735	molecular_function	structural constituent of ribosome
DS	0005840	cellular_component	ribosome
DS	0006412	biological_process	translation
DT	0000028	biological_process	ribosomal small subunit assembly
DT	0000054	biological_process	ribosomal subunit export from nucleus
DT	0003723	molecular_function	RNA binding
DT	0003735	molecular_function	structural constituent of ribosome
DT	0005737	cellular_component	cytoplasm
DT	0005829	cellular_component	cytosol
DT	0005840	cellular_component	ribosome
DT	0006412	biological_process	translation
DT	0022627	cellular_component	cytosolic small ribosomal subunit
DT	0042254	biological_process	ribosome biogenesis
DT	0042274	biological_process	ribosomal small subunit biogenesis
DT	1990904	cellular_component	ribonucleoprotein complex
DW	0002181	biological_process	cytoplasmic translation
DW	0003735	molecular_function	structural constituent of ribosome
DW	0005737	cellular_component	cytoplasm
DW	0005829	cellular_component	cytosol
DW	0005840	cellular_component	ribosome
DW	0006412	biological_process	translation
DW	0022627	cellular_component	cytosolic small ribosomal subunit
DW	1990904	cellular_component	ribonucleoprotein complex
DX	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DX	0003735	molecular_function	structural constituent of ribosome
DX	0005737	cellular_component	cytoplasm
DX	0005829	cellular_component	cytosol
DX	0005840	cellular_component	ribosome
DX	0006412	biological_process	translation
DX	0006450	biological_process	regulation of translational fidelity
DX	0015935	cellular_component	small ribosomal subunit
DX	0022627	cellular_component	cytosolic small ribosomal subunit
DX	1990145	biological_process	maintenance of translational fidelity
DX	1990904	cellular_component	ribonucleoprotein complex
DY	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DY	0002181	biological_process	cytoplasmic translation
DY	0003735	molecular_function	structural constituent of ribosome
DY	0005737	cellular_component	cytoplasm
DY	0005739	cellular_component	mitochondrion
DY	0005829	cellular_component	cytosol
DY	0005840	cellular_component	ribosome
DY	0006412	biological_process	translation
DY	0022627	cellular_component	cytosolic small ribosomal subunit
DY	1990904	cellular_component	ribonucleoprotein complex
DZ	0002181	biological_process	cytoplasmic translation
DZ	0003735	molecular_function	structural constituent of ribosome
DZ	0005737	cellular_component	cytoplasm
DZ	0005829	cellular_component	cytosol
DZ	0005840	cellular_component	ribosome
DZ	0006451	biological_process	translational readthrough
DZ	0022627	cellular_component	cytosolic small ribosomal subunit
DZ	1990904	cellular_component	ribonucleoprotein complex
JD	0000166	molecular_function	nucleotide binding
JD	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JD	0003676	molecular_function	nucleic acid binding
JD	0003723	molecular_function	RNA binding
JD	0003724	molecular_function	RNA helicase activity
JD	0004386	molecular_function	helicase activity
JD	0005515	molecular_function	protein binding
JD	0005524	molecular_function	ATP binding
JD	0005654	cellular_component	nucleoplasm
JD	0005730	cellular_component	nucleolus
JD	0005739	cellular_component	mitochondrion
JD	0006364	biological_process	rRNA processing
JD	0006396	biological_process	RNA processing
JD	0008186	molecular_function	ATP-dependent activity, acting on RNA
JD	0016787	molecular_function	hydrolase activity
JD	0016887	molecular_function	ATP hydrolysis activity
JD	0022613	biological_process	ribonucleoprotein complex biogenesis
JD	0030490	biological_process	maturation of SSU-rRNA
JD	0030686	cellular_component	90S preribosome
JD	0032040	cellular_component	small-subunit processome
JD	0042254	biological_process	ribosome biogenesis
JD	1990904	cellular_component	ribonucleoprotein complex
JF	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JF	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JF	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JF	0003723	molecular_function	RNA binding
JF	0005515	molecular_function	protein binding
JF	0005634	cellular_component	nucleus
JF	0005654	cellular_component	nucleoplasm
JF	0005730	cellular_component	nucleolus
JF	0005737	cellular_component	cytoplasm
JF	0005880	cellular_component	nuclear microtubule
JF	0006364	biological_process	rRNA processing
JF	0008168	molecular_function	methyltransferase activity
JF	0016740	molecular_function	transferase activity
JF	0019843	molecular_function	rRNA binding
JF	0030490	biological_process	maturation of SSU-rRNA
JF	0030686	cellular_component	90S preribosome
JF	0031167	biological_process	rRNA methylation
JF	0032040	cellular_component	small-subunit processome
JF	0032259	biological_process	methylation
JF	0034399	cellular_component	nuclear periphery
JF	0042254	biological_process	ribosome biogenesis
JF	0042274	biological_process	ribosomal small subunit biogenesis
JF	0042802	molecular_function	identical protein binding
JF	0070037	molecular_function	rRNA (pseudouridine) methyltransferase activity
JF	0070475	biological_process	rRNA base methylation
JF	1990904	cellular_component	ribonucleoprotein complex
JG	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JG	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JG	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JG	0003723	molecular_function	RNA binding
JG	0005515	molecular_function	protein binding
JG	0005634	cellular_component	nucleus
JG	0005654	cellular_component	nucleoplasm
JG	0005730	cellular_component	nucleolus
JG	0005737	cellular_component	cytoplasm
JG	0005880	cellular_component	nuclear microtubule
JG	0006364	biological_process	rRNA processing
JG	0008168	molecular_function	methyltransferase activity
JG	0016740	molecular_function	transferase activity
JG	0019843	molecular_function	rRNA binding
JG	0030490	biological_process	maturation of SSU-rRNA
JG	0030686	cellular_component	90S preribosome
JG	0031167	biological_process	rRNA methylation
JG	0032040	cellular_component	small-subunit processome
JG	0032259	biological_process	methylation
JG	0034399	cellular_component	nuclear periphery
JG	0042254	biological_process	ribosome biogenesis
JG	0042274	biological_process	ribosomal small subunit biogenesis
JG	0042802	molecular_function	identical protein binding
JG	0070037	molecular_function	rRNA (pseudouridine) methyltransferase activity
JG	0070475	biological_process	rRNA base methylation
JG	1990904	cellular_component	ribonucleoprotein complex
JH	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JH	0005515	molecular_function	protein binding
JH	0005634	cellular_component	nucleus
JH	0005730	cellular_component	nucleolus
JH	0005737	cellular_component	cytoplasm
JH	0006364	biological_process	rRNA processing
JH	0016973	biological_process	poly(A)+ mRNA export from nucleus
JH	0030490	biological_process	maturation of SSU-rRNA
JH	0030515	molecular_function	snoRNA binding
JH	0030686	cellular_component	90S preribosome
JH	0030688	cellular_component	preribosome, small subunit precursor
JH	0042254	biological_process	ribosome biogenesis
JJ	0000056	biological_process	ribosomal small subunit export from nucleus
JJ	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JJ	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JJ	0003723	molecular_function	RNA binding
JJ	0005634	cellular_component	nucleus
JJ	0005730	cellular_component	nucleolus
JJ	0005737	cellular_component	cytoplasm
JJ	0030490	biological_process	maturation of SSU-rRNA
JJ	0030686	cellular_component	90S preribosome
JJ	0042134	molecular_function	rRNA primary transcript binding
JJ	0042254	biological_process	ribosome biogenesis
JJ	0042255	biological_process	ribosome assembly
JJ	0043248	biological_process	proteasome assembly
JJ	0051082	molecular_function	unfolded protein binding
JL	0000154	biological_process	rRNA modification
JL	0000179	molecular_function	rRNA (adenine-N6,N6-)-dimethyltransferase activity
JL	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JL	0003723	molecular_function	RNA binding
JL	0005730	cellular_component	nucleolus
JL	0005737	cellular_component	cytoplasm
JL	0006364	biological_process	rRNA processing
JL	0008168	molecular_function	methyltransferase activity
JL	0016740	molecular_function	transferase activity
JL	0030686	cellular_component	90S preribosome
JL	0030688	cellular_component	preribosome, small subunit precursor
JL	0031167	biological_process	rRNA methylation
JL	0032259	biological_process	methylation
JL	0042254	biological_process	ribosome biogenesis
JL	0052909	molecular_function	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity
UB	0000028	biological_process	ribosomal small subunit assembly
UB	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UB	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UB	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UB	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UB	0005515	molecular_function	protein binding
UB	0005634	cellular_component	nucleus
UB	0005654	cellular_component	nucleoplasm
UB	0005730	cellular_component	nucleolus
UB	0005739	cellular_component	mitochondrion
UB	0006364	biological_process	rRNA processing
UB	0030490	biological_process	maturation of SSU-rRNA
UB	0030686	cellular_component	90S preribosome
UB	0030688	cellular_component	preribosome, small subunit precursor
UB	0030692	cellular_component	Noc4p-Nop14p complex
UB	0032040	cellular_component	small-subunit processome
UB	0034511	molecular_function	U3 snoRNA binding
UB	0042254	biological_process	ribosome biogenesis
UB	0042274	biological_process	ribosomal small subunit biogenesis
UB	1990904	cellular_component	ribonucleoprotein complex
UC	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UC	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UC	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UC	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UC	0003674	molecular_function	molecular_function
UC	0005515	molecular_function	protein binding
UC	0005634	cellular_component	nucleus
UC	0005654	cellular_component	nucleoplasm
UC	0005730	cellular_component	nucleolus
UC	0006364	biological_process	rRNA processing
UC	0030490	biological_process	maturation of SSU-rRNA
UC	0032040	cellular_component	small-subunit processome
UC	0042254	biological_process	ribosome biogenesis
UC	0042802	molecular_function	identical protein binding
UC	1990904	cellular_component	ribonucleoprotein complex
UN	0000166	molecular_function	nucleotide binding
UN	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UN	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UN	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UN	0005515	molecular_function	protein binding
UN	0005524	molecular_function	ATP binding
UN	0005654	cellular_component	nucleoplasm
UN	0005730	cellular_component	nucleolus
UN	0006364	biological_process	rRNA processing
UN	0008047	molecular_function	enzyme activator activity
UN	0030490	biological_process	maturation of SSU-rRNA
UN	0032040	cellular_component	small-subunit processome
UN	0042254	biological_process	ribosome biogenesis
UN	1990904	cellular_component	ribonucleoprotein complex
US	0042254	biological_process	ribosome biogenesis
UX	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UX	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UX	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UX	0004521	molecular_function	RNA endonuclease activity
UX	0004540	molecular_function	RNA nuclease activity
UX	0005515	molecular_function	protein binding
UX	0005654	cellular_component	nucleoplasm
UX	0005730	cellular_component	nucleolus
UX	0006364	biological_process	rRNA processing
UX	0008270	molecular_function	zinc ion binding
UX	0030490	biological_process	maturation of SSU-rRNA
UX	0032040	cellular_component	small-subunit processome
UX	0042254	biological_process	ribosome biogenesis
UX	0042274	biological_process	ribosomal small subunit biogenesis

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIIkhT

Chain	Residue	Details
DF	GLU91-THR117

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR

Chain	Residue	Details
DW	GLY100-ARG117

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD

Chain	Residue	Details
DO	LEU102-ASP124

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
DX	LYS62-ARG69

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS

Chain	Residue	Details
DL	GLY120-SER132

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL

Chain	Residue	Details
DQ	GLY71-LEU89

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
DN	VAL98-TYR128

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWlLdK

Chain	Residue	Details
DE	HIS8-LYS22

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKSvGFGlVYNSvaeakkfE

Chain	Residue	Details
DY	PHE64-GLU86

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
DG	ILE52-MET63

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PykhidaSgsInRkVLQaLE

Chain	Residue	Details
DT	PRO90-GLU109

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI

Chain	Residue	Details
DJ	LEU105-ILE129

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SsIIIDEAHE

Chain	Residue	Details
JD	SER511-GLU520

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH

Chain	Residue	Details
DH	LYS76-HIS89

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
Dc	GLU58-LEU66

---

site_id	PS01131
Number of Residues	28
Details	RRNA_A_DIMETH Ribosomal RNA adenine dimethylases signature. VLEvGPGtGnLTvriLeqakn...VvAVEmD

Chain	Residue	Details
JL	VAL60-ASP87

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStiLctPtG

Chain	Residue	Details
Db	LYS36-GLY68

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL

Chain	Residue	Details
DA	LEU61-LEU73

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RsaTGAkraqf.RkKrKfELG

Chain	Residue	Details
DI	ARG11-GLY30

---

site_id	PS01287
Number of Residues	11
Details	RTC RNA 3'-terminal phosphate cyclase signature. RGspPlGGGeV

Chain	Residue	Details
CM	ARG156-VAL166

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	83
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	47
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	99
Details	Domain: {"description":"PINc"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	181
Details	Domain: {"description":"Brix","evidences":[{"source":"PROSITE-ProRule","id":"PRU00034","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	165
Details	Domain: {"description":"Bms1-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	9
Details	Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18063569","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	8
Details	Site: {"description":"Interaction with substrate rRNA","evidences":[{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Site: {"description":"Stabilizes Arg-88","evidences":[{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01026","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	52
Details	Domain: {"description":"KH"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	44
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; by RKM1","evidences":[{"source":"PubMed","id":"22522802","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	63
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"15665377","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"30609991","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	74
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P05755","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P05755","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1544921","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"3,4-dihydroxyproline","evidences":[{"source":"PubMed","id":"24550462","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	22
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"S-methylcysteine","evidences":[{"source":"PubMed","id":"22650761","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	179
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	3
Details	Motif: {"description":"DEAH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	18
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---