6ZPR
Solution structure of MLKL executioner domain in complex with a covalent inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue QOK A 201 |
| Chain | Residue |
| A | CYS24 |
| A | ARG82 |
| A | ILE85 |
| A | CYS86 |
| A | LEU89 |
| A | ASP144 |
| A | PHE148 |
| A | LEU151 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 29 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Target of necrosulfonamide inhibitor","evidences":[{"source":"PubMed","id":"22265413","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
