Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue GBS A 301 |
| Chain | Residue |
| A | ASP181 |
| A | GLY218 |
| A | HOH429 |
| A | SER182 |
| A | CYS183 |
| A | GLN184 |
| A | GLY185 |
| A | SER187 |
| A | GLY208 |
| A | GLU210 |
| A | CYS211 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PGE A 302 |
| Chain | Residue |
| A | TRP229 |
| A | SER232 |
| A | PHE233 |
| B | TYR44 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | HIS83 |
| B | ASN91 |
| B | ASN169 |
| B | ARG225 |
| B | PHE226 |
| B | HOH474 |
| B | HOH486 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | GLY10 |
| B | ALA11 |
| B | TRP199 |
| B | HOH443 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 305 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | VAL71 |
| D | ARG73 |
| D | ASN103 |
| D | HOH512 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| D | ASN154 |
| D | HOH413 |
| D | HOH444 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 304 |
| Chain | Residue |
| D | HIS83 |
| D | ASN91 |
| D | ASN169 |
| D | ARG225 |
| D | PHE226 |
| D | HOH430 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide GBS B 301 and SER B 187 |
| Chain | Residue |
| B | CYS26 |
| B | GLY27 |
| B | HIS41 |
| B | CYS42 |
| B | ASP181 |
| B | SER182 |
| B | GLN184 |
| B | GLY185 |
| B | ASP186 |
| B | GLY188 |
| B | GLY189 |
| B | THR205 |
| B | SER206 |
| B | GLY208 |
| B | GLU210 |
| B | CYS211 |
| B | GLY218 |
| B | HOH480 |
| site_id | AD1 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide GBS C 301 and SER C 187 |
| Chain | Residue |
| C | CYS26 |
| C | GLY27 |
| C | HIS41 |
| C | CYS42 |
| C | ASP181 |
| C | SER182 |
| C | GLN184 |
| C | GLY185 |
| C | ASP186 |
| C | GLY188 |
| C | GLY189 |
| C | THR205 |
| C | SER206 |
| C | GLY208 |
| C | GLU210 |
| C | CYS211 |
| C | GLY218 |
| C | HOH417 |
| C | HOH450 |
| site_id | AD2 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide GBS D 301 and SER D 187 |
| Chain | Residue |
| D | CYS26 |
| D | GLY27 |
| D | HIS41 |
| D | CYS42 |
| D | ASP181 |
| D | SER182 |
| D | GLN184 |
| D | GLY185 |
| D | ASP186 |
| D | GLY188 |
| D | GLY189 |
| D | THR205 |
| D | SER206 |
| D | GLY208 |
| D | GLU210 |
| D | CYS211 |
| D | GLY218 |
| D | HOH419 |
| D | HOH469 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL37-CYS42 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLM |
| Chain | Residue | Details |
| A | ASP181-MET192 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS41 | |
| D | HIS41 | |
| D | ASP92 | |
| D | SER187 | |
| A | ASP92 | |
| A | SER187 | |
| B | HIS41 | |
| B | ASP92 | |
| B | SER187 | |
| C | HIS41 | |
| C | ASP92 | |
| C | SER187 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN64 | |
| C | ASN103 | |
| C | ASN125 | |
| C | ASN165 | |
| D | ASN64 | |
| D | ASN103 | |
| D | ASN125 | |
| D | ASN165 | |
| A | ASN103 | |
| A | ASN125 | |
| A | ASN165 | |
| B | ASN64 | |
| B | ASN103 | |
| B | ASN125 | |
| B | ASN165 | |
| C | ASN64 | |
