6ZNP
Crystal Structure of DUF1998 helicase MrfA bound to DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0036297 | biological_process | interstrand cross-link repair |
| A | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006289 | biological_process | nucleotide-excision repair |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0036297 | biological_process | interstrand cross-link repair |
| B | 0043138 | molecular_function | 3'-5' DNA helicase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | CYS718 |
| A | CYS720 |
| A | CYS724 |
| A | CYS727 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CIT A 802 |
| Chain | Residue |
| A | GLU420 |
| A | SER421 |
| A | ARG423 |
| A | HIS655 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| B | CYS720 |
| B | CYS724 |
| B | CYS727 |
| B | CYS718 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 360 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 308 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 420 |
| Details | Region: {"description":"RecA1","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 172 |
| Details | Region: {"description":"RecA2","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 132 |
| Details | Region: {"description":"Winged-helix (WH)","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 130 |
| Details | Region: {"description":"Oligonucleotide/oligosaccharide-binding (OB)","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 73 |
| Details | Region: {"description":"Connector (CON)","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 118 |
| Details | Region: {"description":"MrfA Zn(2+)-binding (MZB)","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6ZNQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZNP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZNQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZNS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Site: {"description":"Salt bridge to E-533","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | Site: {"description":"Salt bridge to R-322","evidences":[{"source":"PubMed","id":"33300032","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
